Epstein Barr Virus LMP2A Monoclonal Antibody (15F9) | Invitrogen MA1-81921 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Epstein Barr Virus LMP2A Monoclonal Antibody (15F9)

catalog :

MA1-81921

quantity :

250 ug

price :

US 480.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

15F9

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Jorapur A, Marshall L, Jacobson S, Xu M, Marubayashi S, Zibinsky M, et al. EBV+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulatory T cell-recruiting chemokines CCL17 and CCL22. PLoS Pathog. 2022;18:e1010200 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Epstein Barr Virus LMP2A Monoclonal Antibody (15F9)

Catalog # :

MA1-81921

Quantity :

250 ug

Price :

US 480.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Virus

Applications :

Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:100-1:1,000

Species :

Virus

Clone :

15F9

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.

Immunogen :

Bacterial TrpE-LMP2A fusion protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:100-1:1,000

Aliases :

EBV