NOTCH1 Monoclonal Antibody (mN1A) | Invitrogen MA1-81888 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NOTCH1 Monoclonal Antibody (mN1A)

catalog :

MA1-81888

quantity :

100 ug

price :

US 292.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

mN1A

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human	Xiong H, Maraver A, Latkowski J, Henderson T, Schlessinger K, Ding Y, et al. Characterization of two distinct lymphoproliferative diseases caused by ectopic expression of the Notch ligand DLL4 on T cells. PLoS ONE. 2013;8:e84841 pubmed publisher
	Zhong L, Sun S, Yao S, Han X, Gu M, Shi J. Histone deacetylase 5 promotes the proliferation and invasion of lung cancer cells. Oncol Rep. 2018;40:2224-2232 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NOTCH1 Monoclonal Antibody (mN1A)

Catalog # :

MA1-81888

Quantity :

100 ug

Price :

US 292.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 10 uL/1x10^6 cells, Immunohistochemistry (Frozen): 1:50-1:200, Western Blot: 1:200-1:1,000

Species :

Human, Mouse

Clone :

mN1A

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures. The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1. Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).

Immunogen :

Synthetic peptide corresponding to cdc10-NCR region within mouse Notch 1.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 10 uL/1x10^6 cells, Immunohistochemistry (Frozen): 1:50-1:200, Western Blot: 1:200-1:1,000

Aliases :

9930111A19Rik; AOS5; AOVD1; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; notch receptor 1; Notch1; p300; RP23-306D20.12; RP23-306D20.12-001; Tan1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1

more info or order :

Invitrogen product webpage