ITGA4 Monoclonal Antibody (Bu49) | Invitrogen MA1-81535 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ITGA4 Monoclonal Antibody (Bu49)

catalog :

MA1-81535

quantity :

200 ug

price :

US 540.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Bu49

reactivity :

human, dogs

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:200	Termini C, Cotter M, Marjon K, Buranda T, Lidke K, Gillette J. The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density. Mol Biol Cell. 2014;25:1560-73 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ITGA4 Monoclonal Antibody (Bu49)

Catalog # :

MA1-81535

Quantity :

200 ug

Price :

US 540.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Canine, Human

Applications :

Flow Cytometry: 1:50-1:200, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent

Species :

Canine, Human

Clone :

Bu49

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains. Alpha4 chain associates with either beta1 or beta7 chain. It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain. These ligands included Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha4beta7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.

Immunogen :

Hyatt myeloma cell line.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:200, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent

Aliases :

269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha

more info or order :

Invitrogen product webpage