product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Calprotectin Monoclonal Antibody (MAC387)
catalog :
MA1-81381
quantity :
100 ug
price :
US 524.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MAC387
reactivity :
guinea pig, domestic goat, human, mouse, rat, dogs, bovine, pigs , cat, domestic rabbit, domestic horse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Invitrogen product webpage
citations: 32
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 3b
Zhu Y, Xing H, Dai D, Kallmes D, Kadirvel R. Differential Interstrain Susceptibility to Vertebrobasilar Dolichoectasia in a Mouse Model. AJNR Am J Neuroradiol. 2017;38:611-616 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 7
Penn J, Mihai D, Washington I. Morphological and physiological retinal degeneration induced by intravenous delivery of vitamin A dimers in rabbits. Dis Model Mech. 2015;8:131-8 pubmed publisher
  • immunohistochemistry; dogs; 1:200
Jung S, Choi S, Cho H, Lee T, Kim T, Jeong W, et al. Polymeric embolization coil of bilayered polyvinyl alcohol strand for therapeutic vascular occlusion: a feasibility study in canine experimental vascular models. J Vasc Interv Radiol. 2015;26:117-23 pubmed publisher
  • immunohistochemistry - paraffin section; pigs ; 1:400
Elgharably H, Ganesh K, Dickerson J, Khanna S, Abas M, Ghatak P, et al. A modified collagen gel dressing promotes angiogenesis in a preclinical swine model of chronic ischemic wounds. Wound Repair Regen. 2014;22:720-9 pubmed publisher
  • immunohistochemistry; pigs ; 1:100
Nedorost L, Uemura H, Furck A, Saeed I, Slavik Z, Kobr J, et al. Vascular histopathologic reaction to pulmonary artery banding in an in vivo growing porcine model. Pediatr Cardiol. 2013;34:1652-60 pubmed publisher
  • immunohistochemistry; human; 1:200
Gahremanpour A, Vela D, Zheng Y, Silva G, Fodor W, Cardoso C, et al. Xenotransplantation of human unrestricted somatic stem cells in a pig model of acute myocardial infarction. Xenotransplantation. 2013;20:110-22 pubmed publisher
  • immunohistochemistry; dogs; 1:200
Jais A, Klein D, Wolfesberger B, Walter I. Gene expression profile of vascular endothelial growth factor (VEGF) and its receptors in various cell types of the canine lymph node using laser capture microdissection (LCM). Vet Immunol Immunopathol. 2011;140:207-14 pubmed publisher
  • immunohistochemistry; bovine
Lu W, Zhang M, Wu Z, Hu T, Xu Z, Liu W, et al. The performance of photooxidatively crosslinked acellular bovine jugular vein conduits in the reconstruction of connections between pulmonary arteries and right ventricles. Biomaterials. 2010;31:2934-43 pubmed publisher
  • immunohistochemistry; mouse
Sumiyoshi M, Sakanaka M, Kimura Y. Chronic intake of a high-cholesterol diet resulted in hepatic steatosis, focal nodular hyperplasia and fibrosis in non-obese mice. Br J Nutr. 2010;103:378-85 pubmed publisher
  • flow cytometry; rat
Gauglitz G, Toliver Kinsky T, Williams F, Song J, Cui W, Herndon D, et al. Insulin increases resistance to burn wound infection-associated sepsis. Crit Care Med. 2010;38:202-8 pubmed publisher
  • immunohistochemistry; pigs ; 1:200
Roy S, Biswas S, Khanna S, Gordillo G, Bergdall V, Green J, et al. Characterization of a preclinical model of chronic ischemic wound. Physiol Genomics. 2009;37:211-24 pubmed publisher
Taylor X, Clark I, Fitzgerald G, Oluoch H, Hole J, DeMattos R, et al. Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer's disease mice. Mol Neurodegener. 2023;18:59 pubmed publisher
Jiang K, Wen X, Pettersson T, Crouzier T. Engineering Surfaces with Immune Modulating Properties of Mucin Hydrogels. ACS Appl Mater Interfaces. 2022;14:39727-39735 pubmed publisher
Du Cheyne C, Martens A, De Spiegelaere W. High Numbers of CD163-Positive Macrophages in the Fibrotic Region of Exuberant Granulation Tissue in Horses. Animals (Basel). 2021;11: pubmed publisher
El Sheikh Ali H, Scoggin K, Ruby R, Loynachan A, Boakari Y, Fernandes C, et al. Equine cervical remodeling during placentitis and the prepartum period: a transcriptomic approach. Reproduction. 2021;161:603-621 pubmed publisher
Rosendorf J, Klicova M, Červenková L, Horakova J, Klapstova A, Hosek P, et al. Reinforcement of Colonic Anastomosis with Improved Ultrafine Nanofibrous Patch: Experiment on Pig. Biomedicines. 2021;9: pubmed publisher
Tee B, Sun Z. Xenogeneic mesenchymal stem cell transplantation for mandibular defect regeneration. Xenotransplantation. 2020;27:e12625 pubmed publisher
Rosendorf J, Horakova J, Klicova M, Palek R, Červenková L, Kural T, et al. Experimental fortification of intestinal anastomoses with nanofibrous materials in a large animal model. Sci Rep. 2020;10:1134 pubmed publisher
Gideon H, Phuah J, Junecko B, Mattila J. Neutrophils express pro- and anti-inflammatory cytokines in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques. Mucosal Immunol. 2019;12:1370-1381 pubmed publisher
Etra J, Grzelak M, Fidder S, Kolegraff K, Bonawitz S, Shores J, et al. A Skin Rejection Grading System for Vascularized Composite Allotransplantation in a Preclinical Large Animal Model. Transplantation. 2019;103:1385-1391 pubmed publisher
Guo G, Zhu Y, Wu Z, Ji H, Lu X, Zhou Y, et al. Circulating monocytes accelerate acute liver failure by IL-6 secretion in monkey. J Cell Mol Med. 2018;22:4056-4067 pubmed publisher
Linard C, Brachet M, Strup Perrot C, l Homme B, Busson E, Squiban C, et al. Autologous Bone Marrow Mesenchymal Stem Cells Improve the Quality and Stability of Vascularized Flap Surgery of Irradiated Skin in Pigs. Stem Cells Transl Med. 2018;7:569-582 pubmed publisher
Wonderlich E, Swan Z, Bissel S, Hartman A, Carney J, O Malley K, et al. Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. J Immunol. 2017;198:1616-1626 pubmed publisher
Phuah J, Wong E, Gideon H, Maiello P, Coleman M, Hendricks M, et al. Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques. Infect Immun. 2016;84:1301-1311 pubmed publisher
Gestrich C, Duerr G, Heinemann J, Meertz A, Probst C, Roell W, et al. Activation of Endocannabinoid System Is Associated with Persistent Inflammation in Human Aortic Aneurysm. Biomed Res Int. 2015;2015:456582 pubmed publisher
O Brien K, Bhatia A, Tsen F, Chen M, Wong A, Woodley D, et al. Identification of the critical therapeutic entity in secreted Hsp90α that promotes wound healing in newly re-standardized healthy and diabetic pig models. PLoS ONE. 2014;9:e113956 pubmed publisher
Wu C, Qiu H, Hu X, Ruan Y, Tian Y, Chu Y, et al. Short-term safety and efficacy of the biodegradable iron stent in mini-swine coronary arteries. Chin Med J (Engl). 2013;126:4752-7 pubmed
Mattila J, Ojo O, Kepka Lenhart D, Marino S, Kim J, Eum S, et al. Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms. J Immunol. 2013;191:773-84 pubmed publisher
Lu M, Zhao S, Liu Q, Jiang S, Song P, Qian H, et al. Transplantation with autologous mesenchymal stem cells after acute myocardial infarction evaluated by magnetic resonance imaging: an experimental study. J Thorac Imaging. 2012;27:125-35 pubmed publisher
Song P, Zhang H, Lu M, Li J, Liu X, Wei Y, et al. Role of cardiopulmonary bypass and arrested heart status in the early cell distribution after intracoronary infusion of bone marrow stromal cells. J Surg Res. 2009;153:66-70 pubmed publisher
Zhang H, Song P, Tang Y, Zhang X, Zhao S, Wei Y, et al. Injection of bone marrow mesenchymal stem cells in the borderline area of infarcted myocardium: heart status and cell distribution. J Thorac Cardiovasc Surg. 2007;134:1234-40 pubmed
Dor F, Gollackner B, Kuwaki K, Ko D, Cooper D, Houser S. Histopathology of spleen allograft rejection in miniature swine. Int J Exp Pathol. 2005;86:57-66 pubmed
product information
Product Type :
Antibody
Product Name :
Calprotectin Monoclonal Antibody (MAC387)
Catalog # :
MA1-81381
Quantity :
100 ug
Price :
US 524.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Bovine, Canine, Deer, Equine, Feline, Goat, Guinea Pig, Human, Non-human primate, Porcine, Rabbit, Rat
Applications :
Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000
Species :
Bovine, Canine, Deer, Equine, Feline, Goat, Guinea Pig, Human, Non-human primate, Porcine, Rabbit, Rat
Clone :
MAC387
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
The S100A8/A9 heterocomplex, also called MRP-8/MRP-14 complex or calprotectin, comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly. The S100A8/A9 complex has antibacterial, antifungal, immunomodulating and antiproliferative effects. Besides this it is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity, like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore calprotectin is also detectable in feces. Elevated levels of calprotectin have been observed in body fluids such as plasma, saliva, gingival crevicular fluid, stools, and synovial fluid during infection and inflammatory conditions.
Immunogen :
Human monocytes.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000
Aliases :
60B8Ag; AI323541; AW546964; B8Ag; BEE11; BEE22; CAGA; CAGB; calcium binding protein; S100 protein; calgranulin A; calgranulin B; calgranulin-A; Calgranulin-B; calprotectin; calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; EGK_01322; EGK_21438; GAGB; intracellular calcium-binding protein (MRP14); L1AG; Leukocyte L1 complex heavy chain; leukocyte L1 complex light chain; LIAG; LOC100735514; LOC532569 protein; MA387; MAC387; macrophage migration inhibitory factor-related protein-14; macrophage migration inhibitory factor-related protein-8; MIF; migration inhibitory factor-related protein 14; Migration inhibitory factor-related protein 8; Mrp14; MRP-14; MRP8; MRP-8; myeloid-related protein 14; Neutrophil cytosolic 23 kDa protein; neutrophil cytosolic 7 kDa protein; NIF; p14; p23; P7; p8; Pro-inflammatory S100 cytokine; protein S100-A8; Protein S100-A9; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium binding protein A9; protein S100-A9; S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100a8; S100A8/S100A9; S100a9; similar to Calgranulin A (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (S100 calcium-binding protein A8) (Calprotectin L1L subunit) (Urinary stone protein band A). ; urinary stone protein band A
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA