RARB Monoclonal Antibody (R beta 28) | Invitrogen MA1-811 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RARB Monoclonal Antibody (R beta 28)

catalog :

MA1-811

quantity :

50 ug

price :

US 414.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

R beta 28

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 4

Reference
Manshouri T, Yang Y, Lin H, Stass S, Glassman A, Keating M, et al. Downregulation of RAR alpha in mice by antisense transgene leads to a compensatory increase in RAR beta and RAR gamma and development of lymphoma. Blood. 1997;89:2507-15 pubmed
Allegretto E, McClurg M, Lazarchik S, Clemm D, Kerner S, Elgort M, et al. Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism. J Biol Chem. 1993;268:26625-33 pubmed
Tairis N, Gabriel J, Gyda M, Soprano K, Soprano D. Arg269 and Lys220 of retinoic acid receptor-beta are important for the binding of retinoic acid. J Biol Chem. 1994;269:19516-22 pubmed
Ali M, Torian B, Vedeckis W. Identification of human, mouse, and rat retinoic acid receptor alpha using monoclonal antibodies. Biochem Biophys Res Commun. 1992;182:1032-9 pubmed

product information

Product Type :

Antibody

Product Name :

RARB Monoclonal Antibody (R beta 28)

Catalog # :

MA1-811

Quantity :

50 ug

Price :

US 414.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:250, Western Blot: 1:500-1:5,000

Species :

Human, Mouse, Rat

Clone :

R beta 28

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Immunogen :

Synthetic peptide corresponding to the C-terminal sequence of the mouse RAR beta.

Format :

Lyophilized

Applications w/Dilutions :

Immunocytochemistry: 1:250, Western Blot: 1:500-1:5,000

Aliases :

A830025K23; HAP; HBV-activated protein; hepatitis B virus activated protein; MCOPS12; NR1B2; nuclear receptor subfamily 1 group B member 2; RAR beta; Rarb; RAR-b; RAR-beta; RARbeta1; RAR-Beta2; RAR-Beta4; RAR-epsilon; retinoic acid; retinoic acid receptor; retinoic acid receptor beta; retinoic acid receptor, beta; retinoic acid receptor, beta polypeptide; RRB2