CD31 Monoclonal Antibody (TLD-3A12) | Invitrogen MA1-81051 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD31 Monoclonal Antibody (TLD-3A12)

catalog :

MA1-81051

quantity :

250 ug

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TLD-3A12

reactivity :

rat, rhesus macaque

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat	Jones A, Stutz C, Zhou Y, Marks J, Shusta E. Identifying blood-brain-barrier selective single-chain antibody fragments. Biotechnol J. 2014;9:664-74 pubmed publisher
immunohistochemistry; rat	Ammar H, Saba S, Ammar R, Elsayed L, Ghaly W, Dhingra S. Erythropoietin protects against doxorubicin-induced heart failure. Am J Physiol Heart Circ Physiol. 2011;301:H2413-21 pubmed publisher
	Bhandari S, Li R, Simon Santamaria J, McCourt P, Johansen S, Smedsrød B, et al. Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages. BMC Mol Cell Biol. 2020;21:85 pubmed publisher
	Deng Z, Zhou L, Wang Y, Liao S, Huang Y, Shan Y, et al. Astrocyte-derived VEGF increases cerebral microvascular permeability under high salt conditions. Aging (Albany NY). 2020;12:11781-11793 pubmed publisher
	Lin F, Zeng Z, Song Y, Li L, Wu Z, Zhang X, et al. YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT. Stem Cell Res Ther. 2019;10:263 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD31 Monoclonal Antibody (TLD-3A12)

Catalog # :

MA1-81051

Quantity :

250 ug

Price :

US 484.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Rat, Rhesus Monkey

Applications :

ELISA: Assay-dependent, Flow Cytometry: 1:10-1:100, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:10-1:100, Western Blot: 1:1,000

Species :

Rat, Rhesus Monkey

Clone :

TLD-3A12

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Immunogen :

Activated, Lewis rat derived microglial cells.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: 1:10-1:100, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1:10-1:100, Western Blot: 1:1,000

Aliases :

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

more info or order :

Invitrogen product webpage