ICAM-1 Monoclonal Antibody (15.2) | Invitrogen MA1-80910 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ICAM-1 Monoclonal Antibody (15.2)

catalog :

MA1-80910

quantity :

200 ug

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

15.2

reactivity :

human, pigs

application :

ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; pigs	Kim H, Kee P, Rim Y, Moody M, Klegerman M, Vela D, et al. Nitric oxide improves molecular imaging of inflammatory atheroma using targeted echogenic immunoliposomes. Atherosclerosis. 2013;231:252-60 pubmed publisher
immunohistochemistry; human; 20 ug/ml	Hromatka B, Ngeleza S, Adibi J, Niles R, Tshefu A, Fisher S. Histopathologies, immunolocalization, and a glycan binding screen provide insights into Plasmodium falciparum interactions with the human placenta. Biol Reprod. 2013;88:154 pubmed publisher
immunohistochemistry; human	Abreu Velez A, Howard M, Hashimoto T. Palm tissue displaying a polyclonal autoimmune response in patients affected by a new variant of endemic pemphigus foliaceus in Colombia, South America. Eur J Dermatol. 2010;20:74-81 pubmed publisher
immunohistochemistry; human; 1:5000	Kurt M, Zulfikaroglu E, Ucankus N, Omeroglu S, Ozcan U. Expression of intercellular adhesion molecule-1 in umbilical and placental vascular tissue of gestational diabetic and normal pregnancies. Arch Gynecol Obstet. 2010;281:71-6 pubmed publisher
immunocytochemistry; human	Huegel R, Velasco P, De La Luz Sierra M, Christophers E, Schröder J, Schwarz T, et al. Novel anti-inflammatory properties of the angiogenesis inhibitor vasostatin. J Invest Dermatol. 2007;127:65-74 pubmed
	Zelter T, Strahilevitz J, Simantov K, Yajuk O, Adams Y, Ramstedt Jensen A, et al. Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria. EMBO Rep. 2022;23:e53641 pubmed publisher
	Chong D, Rebeyrol C, José R, Williams A, Brown J, Scotton C, et al. ICAM-1 and ICAM-2 Are Differentially Expressed and Up-Regulated on Inflamed Pulmonary Epithelium, but Neither ICAM-2 nor LFA-1: ICAM-1 Are Required for Neutrophil Migration Into the Airways In Vivo. Front Immunol. 2021;12:691957 pubmed publisher
	Chevrier S, Levine J, Zanotelli V, Silina K, Schulz D, Bacac M, et al. An Immune Atlas of Clear Cell Renal Cell Carcinoma. Cell. 2017;169:736-749.e18 pubmed publisher
	Sackstein R, Schatton T, Barthel S. T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy. Lab Invest. 2017;97:669-697 pubmed publisher
	Klegerman M, Zou Y, Golunski E, Peng T, Huang S, McPherson D. Use of thermodynamic coupling between antibody-antigen binding and phospholipid acyl chain phase transition energetics to predict immunoliposome targeting affinity. J Liposome Res. 2014;24:216-22 pubmed publisher
	Hamilton A, Huang S, Warnick D, Rabbat M, Kane B, Nagaraj A, et al. Intravascular ultrasound molecular imaging of atheroma components in vivo. J Am Coll Cardiol. 2004;43:453-60 pubmed

product information

Product Type :

Antibody

Product Name :

ICAM-1 Monoclonal Antibody (15.2)

Catalog # :

MA1-80910

Quantity :

200 ug

Price :

US 480.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Porcine

Applications :

Flow Cytometry: 1:50-1:100, Immunohistochemistry (Frozen): 1:50-1:100, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent

Species :

Human, Porcine

Clone :

15.2

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.

Immunogen :

Human monocytes.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:100, Immunohistochemistry (Frozen): 1:50-1:100, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent

Aliases :

BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells

more info or order :

Invitrogen product webpage