CD16 Monoclonal Antibody (1D3), FITC | Invitrogen MA1-80881 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD16 Monoclonal Antibody (1D3), FITC

catalog :

MA1-80881

quantity :

100Tests

price :

US 518

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

1D3

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

CD16 Monoclonal Antibody (1D3), FITC

Catalog # :

MA1-80881

Quantity :

100Tests

Price :

US 518

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Neat

Species :

Human

Clone :

1D3

Isotype :

IgM

Storage :

4°C or -20°C if preferred, store in dark

Description :

CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.

Immunogen :

Human granulocytes.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Neat

Aliases :

CD16, CD16b, FCG3, FCGR3, FCGR3B, Fc gamma Receptor III-b, Fc gamma Receptor 3b