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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Influenza A M1 Monoclonal Antibody (GA2B)
catalog :
MA1-80736
quantity :
1 mg
price :
US 546.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GA2B
reactivity :
Alphainfluenzavirus
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; Alphainfluenzavirus; 1:4000; fig 5
Hayashi T, Wills S, Bussey K, Takimoto T. Identification of Influenza A Virus PB2 Residues Involved in Enhanced Polymerase Activity and Virus Growth in Mammalian Cells at Low Temperatures. J Virol. 2015;89:8042-9 pubmed publisher
  • western blot; Alphainfluenzavirus
Fournier G, Chiang C, Munier S, Tomoiu A, Demeret C, Vidalain P, et al. Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicing. PLoS Pathog. 2014;10:e1004164 pubmed publisher
van de Ven K, Lanfermeijer J, van Dijken H, Muramatsu H, Vilas Boas de Melo C, Lenz S, et al. A universal influenza mRNA vaccine candidate boosts T cell responses and reduces zoonotic influenza virus disease in ferrets. Sci Adv. 2022;8:eadc9937 pubmed publisher
Ashtiwi N, Sarr D, Nagy T, Reneer Z, Tripp R, Rada B. The Hypothiocyanite and Amantadine Combination Treatment Prevents Lethal Influenza A Virus Infection in Mice. Front Immunol. 2022;13:859033 pubmed publisher
Selzer L, Su Z, Pintilie G, Chiu W, Kirkegaard K. Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer. PLoS Biol. 2020;18:e3000827 pubmed publisher
Jacobs N, Onuoha N, Antia A, Steel J, Antia R, Lowen A. Incomplete influenza A virus genomes occur frequently but are readily complemented during localized viral spread. Nat Commun. 2019;10:3526 pubmed publisher
Rahim M, Klewes L, Zahedi Amiri A, Mai S, Coombs K. Global Interactomics Connect Nuclear Mitotic Apparatus Protein NUMA1 to Influenza Virus Maturation. Viruses. 2018;10: pubmed publisher
product information
Product Type :
Antibody
Product Name :
Influenza A M1 Monoclonal Antibody (GA2B)
Catalog # :
MA1-80736
Quantity :
1 mg
Price :
US 546.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Virus
Applications :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent
Species :
Virus
Clone :
GA2B
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Influenza A virus matrix 1, M1, is a critical protein required for assembly and budding. Hemagglutinin associates with M1 via its cytoplasmic tail and transmembrane domain. The M2 and nucleoprotein proteins are critical in the replication cycle of influenza viruses. The M2 channel protein is an essential component of the viral envelope because of its ability to form a highly selective, pH-regulated, proton-conducting channel. The M2 channel allows protons to enter the interior of the virus and acidification weakens the interaction of the M1 protein with the ribonuclear core.
Immunogen :
Influenza A / Puerto Rico / 8 / 34 (H1N1) and A/Bangkok / 1 / 79 (H3N2) viruses.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent
Aliases :
Influenza M1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA