J Chain Monoclonal Antibody (Mc19-9) | Invitrogen MA1-80527 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

J Chain Monoclonal Antibody (Mc19-9)

catalog :

MA1-80527

quantity :

200 ug

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Mc19-9

The same clone is also sold as:

Bio-Rad: MCA693
OriGene: SM1013P

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section

citations: 3

Reference
Zheng Y, Lu P, Deng Y, Wen L, Wang Y, Ma X, et al. Single-Cell Transcriptomics Reveal Immune Mechanisms of the Onset and Progression of IgA Nephropathy. Cell Rep. 2020;33:108525 pubmed publisher
Palací J, Virdi V, Depicker A. Transformation strategies for stable expression of complex hetero-multimeric proteins like secretory immunoglobulin A in plants. Plant Biotechnol J. 2019;17:1760-1769 pubmed publisher
Edman M, Janga S, Meng Z, Bechtold M, Chen A, Kim C, et al. Increased Cathepsin S activity associated with decreased protease inhibitory capacity contributes to altered tear proteins in Sjögren's Syndrome patients. Sci Rep. 2018;8:11044 pubmed publisher

product information

Product Type :

Antibody

Product Name :

J Chain Monoclonal Antibody (Mc19-9)

Catalog # :

MA1-80527

Quantity :

200 ug

Price :

US 480.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 5 ug/mL, Immunohistochemistry (Frozen): 1:200, Immunoprecipitation: 20 ug/mL, Western Blot: Assay-dependent

Species :

Human

Clone :

Mc19-9

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.

Immunogen :

Human J Chain.

Format :

Liquid

Applications w/Dilutions :

ELISA: 5 ug/mL, Immunohistochemistry (Frozen): 1:200, Immunoprecipitation: 20 ug/mL, Western Blot: Assay-dependent

Aliases :

9530090F24Rik; AI323815; IGCJ; Igj; IgJ chain; immunoglobulin J chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; immunoglobulin joining chain; immunoglobulin joining gene (not J region); J chain; Jch; JCHAIN; Joining chain of multimeric IgA and IgM