This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Integrin alpha V + Integrin beta-3 Monoclonal Antibody (23C6)
catalog :
MA1-80501
quantity :
1 mg
price :
US 799
clonality :
monoclonal
host :
mouse
clone name :
23C6
reactivity :
human, chicken
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments
citations: 3
Published Application/Species/DilutionReference
  • immunocytochemistry; human
Kotake S, Yago T, Kawamoto M, Nanke Y. Voltage-dependent anion channels (VDACs, porin) expressed in the plasma membrane regulate the differentiation and function of human osteoclasts. Cell Biol Int. 2013;37:65-77 pubmed publisher
  • neutralization; human
Bermudez L, Sangari F, Kolonoski P, Petrofsky M, Goodman J. The efficiency of the translocation of Mycobacterium tuberculosis across a bilayer of epithelial and endothelial cells as a model of the alveolar wall is a consequence of transport within mononuclear phagocytes and invasion of alveolar epithelial cells. Infect Immun. 2002;70:140-6 pubmed
Kotake S, Nanke Y, Kawamoto M, Yago T, Udagawa N, Ichikawa N, et al. T-cell leukemia translocation-associated gene (TCTA) protein is required for human osteoclastogenesis. Bone. 2009;45:627-39 pubmed publisher
product information
Product Type :
MA1-80501
Product Name :
Integrin alpha V + Integrin beta-3 Monoclonal Antibody (23C6)
Catalog # :
MA1-80501
Quantity :
1 mg
Price :
US 799
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Chicken, Human
Applications :
Flow Cytometry, Immunohistochemistry (Frozen) and Immunoprecipitation
Species :
Ck, Hu
Clone :
23C6
Gene Identification :
Entrez: 396420, 3690, 3685; Uniprot: P26008, P05106, P06756
Isotype :
IgG1
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Immunogen :
Osteoclasts from osteoclastomas.
Format :
Liquid; PBS with no preservative
Applications w/Dilutions :
FACS 1/50-1/100, IHC (F) Assay Dependent, IP Assay Dependent
Aliases :
ITGAV, ITGB3, CD51, MSK8, VNRA, VTNR, integrin alpha-V, integrin alphaVbeta3, antigen CD51, vitronectin receptor subunit alpha, CD61, GP3A, GPIIIa
PubMed References :
19560569
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
www.thermofisher.com
800-678-5599
headquarters: USA