This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD62E/CD62P Monoclonal Antibody (1.2B6)
catalog :
MA1-80430
quantity :
200 ug
price :
US 592.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1.2B6

The same clone is also sold as:
reactivity :
human, pigs
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
citations: 2
Reference
Biedermann T, Lametschwandtner G, Tangemann K, Kund J, Hinteregger S, Carballido Perrig N, et al. IL-12 instructs skin homing of human Th2 cells. J Immunol. 2006;177:3763-70 pubmed
Ku C, Zerboni L, Ito H, Graham B, Wallace M, Arvin A. Varicella-zoster virus transfer to skin by T Cells and modulation of viral replication by epidermal cell interferon-alpha. J Exp Med. 2004;200:917-25 pubmed
product information
Product Type :
Antibody
Product Name :
CD62E/CD62P Monoclonal Antibody (1.2B6)
Catalog # :
MA1-80430
Quantity :
200 ug
Price :
US 592.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human, Porcine
Applications :
ELISA: 10 ug/mL, Flow Cytometry: 10 ug/mL, Immunohistochemistry (Frozen): 1-10 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Species :
Human, Porcine
Clone :
1.2B6
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues.CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140. It is expressed on platelets, megakaryocytes, and epithelium. It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis. The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P.
Immunogen :
Human E-Selectin (ELAM-1).
Format :
Liquid
Applications w/Dilutions :
ELISA: 10 ug/mL, Flow Cytometry: 10 ug/mL, Immunohistochemistry (Frozen): 1-10 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Aliases :
CD62; CD62 antigen-like family member E; CD62 antigen-like family member P; CD62E; CD62P; CD62P; CD62 homolog; ELAM; ELAM1; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule 1; ESEL; E-selectin; GMP140; GMP-140; GMRP; Granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; GRMP; LECAM2; LECAM-2; LECAM3; LECAM-3; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; Leukocyte-endothelial cell adhesion molecule 3; PADGEM; Platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; P-selectin; P-selectin precursor; RP1-117P20.2; SELE; selectin E; selectin E (endothelial adhesion molecule 1); selectin P; selectin P (granule membrane protein 140kDa, antigen CD62); SELP
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA