Aurora A Monoclonal Antibody (35C1) | Invitrogen MA1-80399 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Aurora A Monoclonal Antibody (35C1)

catalog :

MA1-80399

quantity :

100µg

price :

US 390

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

35C1

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Rizkallah R, Batsomboon P, Dudley G, Hurt M. Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins. Oncotarget. 2015;6:1446-61 pubmed
	Wike C, Graves H, Hawkins R, Gibson M, Ferdinand M, Zhang T, et al. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. elife. 2016;5:e11402 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Aurora A Monoclonal Antibody (35C1)

Catalog # :

MA1-80399

Quantity :

100µg

Price :

US 390

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ChIP assay: 1-5 µg, Immunofluorescence: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1/500-1/1000

Species :

Human, Mouse

Clone :

35C1

Isotype :

IgG2b

Storage :

4°C or -20°C if preferred

Description :

Aurora A is a 46 kDa protein that plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Multiple transcript variants encoding the same protein have been found for this gene. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal.

Immunogen :

Recombinant Aurora A

Format :

Liquid

Applications w/Dilutions :

ChIP assay: 1-5 µg, Immunofluorescence: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1/500-1/1000

Aliases :

AIK, ARK1, AURA, AURORA2, BTAK, MGC34538, STK15, STK6, STK7