CD31 Monoclonal Antibody (TLD-3A12) | Invitrogen MA1-80069 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD31 Monoclonal Antibody (TLD-3A12)

catalog :

MA1-80069

quantity :

100 ug

price :

US 292.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TLD-3A12

reactivity :

rat, rhesus macaque

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat	Tian G, Sun K, Huang P, Zhou C, Yao H, Huo Z, et al. Long-Term Stimulation with Electroacupuncture at DU20 and ST36 Rescues Hippocampal Neuron through Attenuating Cerebral Blood Flow in Spontaneously Hypertensive Rats. Evid Based Complement Alternat Med. 2013;2013:482947 pubmed publisher
immunohistochemistry; rat	Ammar H, Saba S, Ammar R, Elsayed L, Ghaly W, Dhingra S. Erythropoietin protects against doxorubicin-induced heart failure. Am J Physiol Heart Circ Physiol. 2011;301:H2413-21 pubmed publisher
	Lee H, Abueva C, Padalhin A, Park S, Ryu H, Chung P, et al. Regeneration of taste through sonic hedgehog upregulation by photobiomodulation. J Biophotonics. 2023;16:e202300043 pubmed publisher
	Zheng G, Harms A, Tail M, Zhang H, Nimmo A, Skutella T, et al. Effects of a neurokinin-1 receptor antagonist in the acute phase after thoracic spinal cord injury in a rat model. Front Mol Neurosci. 2023;16:1128545 pubmed publisher
	Ding J, Zhao J, Wang L, Chen X, Jiang D, Qin M, et al. Regulated contribution of local and systemic immunity to new bone regeneration by modulating B/Sr concentration of bioactive borosilicate glass. Mater Today Bio. 2023;19:100585 pubmed publisher
	Yin G, Wang J, Zhong Y, Wu W. Propofol suppresses adipose-derived stem cell progression via PI3K/AKT-Wnt signaling pathway. BMC Anesthesiol. 2022;22:65 pubmed publisher
	Dhall S, Park M, Li C, Sathyamoorthy M. Regenerative Effects of Hypoxia Primed Flowable Placental Formulation in Muscle and Dermal Injury. Int J Mol Sci. 2021;22: pubmed publisher
	Zhang C, Lu W, Luo X, Liu S, Li Y, Zheng Q, et al. Mitomycin C induces pulmonary vascular endothelial-to-mesenchymal transition and pulmonary veno-occlusive disease via Smad3-dependent pathway in rats. Br J Pharmacol. 2021;178:217-235 pubmed publisher
	Jiang Q, Liu C, Liu S, Lu W, Li Y, Luo X, et al. Dysregulation of BMP9/BMPR2/SMAD signalling pathway contributes to pulmonary fibrosis and pulmonary hypertension induced by bleomycin in rats. Br J Pharmacol. 2021;178:203-216 pubmed publisher
	Jiao Y, Huang P, Yan L, Sun K, Pan C, Li Q, et al. YangXue QingNao Wan, a Compound Chinese Medicine, Attenuates Cerebrovascular Hyperpermeability and Neuron Injury in Spontaneously Hypertensive Rat: Effect and Mechanism. Front Physiol. 2019;10:1246 pubmed publisher
	Gu Y, Huang P, Li Q, Liu Y, Liu G, Wang Y, et al. YangXue QingNao Wan and Silibinin Capsules, the Two Chinese Medicines, Attenuate Cognitive Impairment in Aged LDLR (+/-) Golden Syrian Hamsters Involving Protection of Blood Brain Barrier. Front Physiol. 2018;9:658 pubmed publisher
	Li Y, Li Q, Pan C, Yan L, Hu B, Liu Y, et al. Bushen Huoxue Attenuates Diabetes-Induced Cognitive Impairment by Improvement of Cerebral Microcirculation: Involvement of RhoA/ROCK/moesin and Src Signaling Pathways. Front Physiol. 2018;9:527 pubmed publisher
	Patel D, Knowell A, Korang Yeboah M, Sharma P, Joshi J, Glymph S, et al. Inhibitor of differentiation 4 (ID4) inactivation promotes de novo steroidogenesis and castration-resistant prostate cancer. Mol Endocrinol. 2014;28:1239-53 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD31 Monoclonal Antibody (TLD-3A12)

Catalog # :

MA1-80069

Quantity :

100 ug

Price :

US 292.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Rat, Rhesus Monkey

Applications :

ELISA: Assay-dependent, Flow Cytometry: 1:10-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1:10-1:100, Western Blot: 1:1,000

Species :

Rat, Rhesus Monkey

Clone :

TLD-3A12

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Immunogen :

Activated, Lewis rat derived microglial cells.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: 1:10-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1:10-1:100, Western Blot: 1:1,000

Aliases :

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

more info or order :

Invitrogen product webpage