TIMP1 Monoclonal Antibody (F31 P2 A5) | Invitrogen MA1-773 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TIMP1 Monoclonal Antibody (F31 P2 A5)

catalog :

MA1-773

quantity :

100 ug

price :

US 440.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

F31 P2 A5

reactivity :

human, mouse, rhesus macaque

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 4b	Yi R, Zhang J, Sun P, Qian Y, Zhao X. Protective Effects of Kuding Tea (Ilex kudingcha C. J. Tseng) Polyphenols on UVB-Induced Skin Aging in SKH1 Hairless Mice. Molecules. 2019;24: pubmed publisher
western blot; mouse; fig 3	Wagner J, Jaurich H, Wallner C, Abraham S, Becerikli M, Dadras M, et al. Diminished bone regeneration after debridement of posttraumatic osteomyelitis is accompanied by altered cytokine levels, elevated B cell activity, and increased osteoclast activity. J Orthop Res. 2017;35:2425-2434 pubmed publisher
western blot; mouse; 1:500; loading ...; fig 6	Chauhan P, Dash D, Singh R. Intranasal Curcumin Inhibits Pulmonary Fibrosis by Modulating Matrix Metalloproteinase-9 (MMP-9) in Ovalbumin-Induced Chronic Asthma. Inflammation. 2017;40:248-258 pubmed publisher
immunohistochemistry; mouse; 1:50	Zion O, Genin O, Kawada N, Yoshizato K, Roffe S, Nagler A, et al. Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention. Pancreas. 2009;38:427-35 pubmed publisher
	Chang J, Zhang W. Remifentanil modulates the TLR4‑mediated MMP‑9/TIMP1 balance and NF‑κB/STAT3 signaling in LPS‑induced A549 cells. Exp Ther Med. 2023;25:79 pubmed publisher
	Wang X, Zhang D, Fucci Q, Dollery C, Owen C. Surface-bound matrix metalloproteinase-8 on macrophages: Contributions to macrophage pericellular proteolysis and migration through tissue barriers. Physiol Rep. 2021;9:e14778 pubmed publisher
	Wang E, Liao Z, Wang L, Liao Y, Xu X, Liu P, et al. A combination of pirfenidone and TGF-β inhibition mitigates cystic echinococcosis-associated hepatic injury. Parasitology. 2021;148:767-778 pubmed publisher
	Zhang Q, Tran T, Wang M, Ranek M, Kokkonen Simon K, Gao J, et al. Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis. Nat Commun. 2018;9:5230 pubmed publisher
	Qian Y, Song J, Sun P, Yi R, Liu H, Feng X, et al. Lactobacillus casei Strain Shirota Enhances the In Vitro Antiproliferative Effect of Geniposide in Human Oral Squamous Carcinoma HSC-3 Cells. Molecules. 2018;23: pubmed publisher
	Jia P, Zhang X, Zuo H, Lu X, Li L. Articular cartilage degradation is prevented by tanshinone IIA through inhibiting apoptosis and the expression of inflammatory cytokines. Mol Med Rep. 2017;16:6285-6289 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TIMP1 Monoclonal Antibody (F31 P2 A5)

Catalog # :

MA1-773

Quantity :

100 ug

Price :

US 440.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse, Rhesus Monkey

Applications :

Immunocytochemistry: 1-2 ug/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:250-1:1,000

Species :

Human, Mouse, Rhesus Monkey

Clone :

F31 P2 A5

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.

Immunogen :

Synthetic peptide corresponding to residues F(72) Q A L G D A A D I R(82) of mouse TIMP-1.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1-2 ug/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:250-1:1,000

Aliases :

CLGI; collagenase inhibitor; Collagenase inhibitor 16C8 fibroblast; EG-1; Embryogenin-1; EPA; EPO; erythroid potentiating activity; erythroid-potentiating activity; Fibroblast collagenase inhibitor; FLJ90373; HCI; Metalloproteinase inhibitor; metalloproteinase inhibitor 1; metalloproteinase tissue inhibitor; metalloproteinase tissue inhibitor 1; MMP inhibitor; RP1-230G1.3; Timp; TIMP 1; TIMP metallopeptidase inhibitor 1; TIMP1; TIMP-1; TIMP-1 protein; tissue inhibitor of matrix metalloproteinase-1; tissue inhibitor of metal proteinases; tissue inhibitor of metallopeptidase 1; tissue inhibitor of metalloproteinase; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); tissue inhibitor of metalloproteinase-1; tissue inhibitor of metalloproteinases; tissue inhibitor of metalloproteinases 1; TPA-induced protein; TPA-S1

more info or order :

Invitrogen product webpage