Transferrin Receptor Monoclonal Antibody (ICO-92) | Invitrogen MA1-7657 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Transferrin Receptor Monoclonal Antibody (ICO-92)

catalog :

MA1-7657

quantity :

100 ug

price :

US 442.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ICO-92

reactivity :

human

application :

flow cytometry

citations: 5

Reference
Deng K, Lu Y, Finnema S, Vangjeli K, Huang J, Huang L, et al. Application of In vitro transcytosis models to brain targeted biologics. PLoS ONE. 2023;18:e0289970 pubmed publisher
Silva F, Sitia L, Allevi R, Bonizzi A, Sevieri M, Morasso C, et al. Combined Method to Remove Endotoxins from Protein Nanocages for Drug Delivery Applications: The Case of Human Ferritin. Pharmaceutics. 2021;13: pubmed publisher
Sitia L, Sevieri M, Bonizzi A, Allevi R, Morasso C, Foschi D, et al. Development of Tumor-Targeted Indocyanine Green-Loaded Ferritin Nanoparticles for Intraoperative Detection of Cancers. ACS Omega. 2020;5:12035-12045 pubmed publisher
Bonizzi A, Truffi M, Sevieri M, Allevi R, Sitia L, Ottria R, et al. Everolimus Nanoformulation in Biological Nanoparticles Increases Drug Responsiveness in Resistant and Low-Responsive Breast Cancer Cell Lines. Pharmaceutics. 2019;11: pubmed publisher
Mazzucchelli S, Truffi M, Baccarini F, Beretta M, Sorrentino L, Bellini M, et al. H-Ferritin-nanocaged olaparib: a promising choice for both BRCA-mutated and sporadic triple negative breast cancer. Sci Rep. 2017;7:7505 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Transferrin Receptor Monoclonal Antibody (ICO-92)

Catalog # :

MA1-7657

Quantity :

100 ug

Price :

US 442.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-dependent

Species :

Human

Clone :

ICO-92

Isotype :

IgG2a

Storage :

4 C short term, -80 C long term

Description :

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

Immunogen :

Transferrin receptor on activated T-B-cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent

Aliases :

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr