Hepatitis B Virus Core Antigen Monoclonal Antibody (1-5) | Invitrogen MA1-7607 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Hepatitis B Virus Core Antigen Monoclonal Antibody (1-5)

catalog :

MA1-7607

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5-Jan

reactivity :

Hepatitis B virus

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; Hepatitis B virus	Cui X, Ludgate L, Ning X, Hu J. Maturation-associated destabilization of hepatitis B virus nucleocapsid. J Virol. 2013;87:11494-503 pubmed publisher
	Jhajharia S, Lai F, Low H, Purushotorman K, Shunmuganathan B, Chan C, et al. Defining the specificity and function of a human neutralizing antibody for Hepatitis B virus. NPJ Vaccines. 2022;7:121 pubmed publisher
	Popescu M, Patriche D, Dobrica M, Pantazica A, Flintoaca Alexandru P, Rouill xe9 Y, et al. Sac1 phosphatidylinositol 4-phosphate phosphatase is a novel host cell factor regulating hepatitis B virus particles assembly and release. FEBS J. 2022;289:7486-7499 pubmed publisher
	Locatelli M, Quivy J, Chapus F, Michelet M, Fresquet J, Maadadi S, et al. HIRA Supports Hepatitis B Virus Minichromosome Establishment and Transcriptional Activity in Infected Hepatocytes. Cell Mol Gastroenterol Hepatol. 2022;14:527-551 pubmed publisher
	Nagornykh A, Tyumentseva M, Tyumentsev A, Akimkin V. Protocol for chronic hepatitis B virus infection mouse model development by patient-derived orthotopic xenografts. PLoS ONE. 2022;17:e0264266 pubmed publisher
	Chabrolles H, Auclair H, Vegna S, Lahlali T, Pons C, Michelet M, et al. Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production. PLoS Pathog. 2020;16:e1008593 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Hepatitis B Virus Core Antigen Monoclonal Antibody (1-5)

Catalog # :

MA1-7607

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Virus

Applications :

ELISA: 1:500, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000

Species :

Virus

Clone :

5-Jan

Isotype :

IgG2b

Storage :

4 C short term, -80 C long term

Description :

The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. Hepatitis B virus is spherical in shape with a diameter of 42nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.

Immunogen :

Purified recombinant HBcAg.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:500, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000

Aliases :

ayw; HBc; HBcAg; HBV; HepB

more info or order :

Invitrogen product webpage