Nonspecific Cytotoxic Cell Monoclonal Antibody (5C.6) | Invitrogen MA1-760 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nonspecific Cytotoxic Cell Monoclonal Antibody (5C.6)

catalog :

MA1-760

quantity :

200 ug

price :

US 399.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5C.6

application :

western blot, ELISA, immunoprecipitation, flow cytometry

citations: 4

Reference
Viveiros M, Antczak D. Characterization of equine natural killer and IL-2 stimulated lymphokine activated killer cell populations. Dev Comp Immunol. 1999;23:521-32 pubmed
Raymond C, Wilkie B, Mallard B, Quinton M. Natural killer cell frequency and function in Yorkshire pigs selectively bred for high or low antibody and cell-mediated immune response. Nat Immun. 1998;16:127-36 pubmed
Evans D, Leary J, Jaso Friedmann L. Nonspecific cytotoxic cell receptor protein-1: a novel (predicted) type III membrane receptor on the teleost equivalent of natural killer cells recognizes conventional antigen. Cell Immunol. 1998;187:19-26 pubmed
Jaso Friedmann L, Leary J, Evans D. NCCRP-1: a novel receptor protein sequenced from teleost nonspecific cytotoxic cells. Mol Immunol. 1997;34:955-65 pubmed

product information

Product Type :

Antibody

Product Name :

Nonspecific Cytotoxic Cell Monoclonal Antibody (5C.6)

Catalog # :

MA1-760

Quantity :

200 ug

Price :

US 399.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Many

Applications :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunoprecipitation: Assay-dependent, Inhibition Assays: Assay-dependent, Western Blot: 10 ug/mL

Species :

Many

Clone :

5C.6

Isotype :

IgM

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Non-specific cytotoxic cells (NCCs) in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. One such property is that NCC/natural killer (NK)/lymphokine activated killer (LAK) cells express spontaneous, non-major histocompatibility complex restricted cytotoxic activity. NCC and LAK lyse a variety of transformed murine and human B-cell, T-cell and myeloid targets. A 32 kDa membrane protein [non-specific cytotoxic cell receptor protein (NCCRP-1)] expressed by NCC and certain mammalian NK/LAK cells mediates this cytotoxicity. NCCRP-1 is evolutionarily conserved and is found in species ranging from marine and freshwater teleosts to higher mammals.

Immunogen :

Purified NCC cells from catfish.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunoprecipitation: Assay-dependent, Inhibition Assays: Assay-dependent, Western Blot: 10 ug/mL

Aliases :

Natural Killer Cell; NCC/NK