RAPSN Monoclonal Antibody (1234) | Invitrogen MA1-746 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RAPSN Monoclonal Antibody (1234)

catalog :

MA1-746

quantity :

100 ug

price :

US 451.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1234

reactivity :

human, mouse, rat, chicken

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000 immunocytochemistry; human; 1:500	Osman A, Schrader A, Hawkes A, Akil O, Bergeron A, Lustig L, et al. Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner ear. Mol Cell Neurosci. 2008;38:153-69 pubmed publisher
	Chan Z, Deng L, Lee C. Grp94 Regulates the Recruitment of Aneural AChR Clusters for the Assembly of Postsynaptic Specializations by Modulating ADF/Cofilin Activity and Turnover. Eneuro. 2020;7: pubmed publisher
	Jacobson C, Côté P, Rossi S, Rotundo R, Carbonetto S. The dystroglycan complex is necessary for stabilization of acetylcholine receptor clusters at neuromuscular junctions and formation of the synaptic basement membrane. J Cell Biol. 2001;152:435-50 pubmed
	Marchand S, Bignami F, Stetzkowski Marden F, Cartaud J. The myristoylated protein rapsyn is cotargeted with the nicotinic acetylcholine receptor to the postsynaptic membrane via the exocytic pathway. J Neurosci. 2000;20:521-8 pubmed
	Dai Z, Peng H. A role of tyrosine phosphatase in acetylcholine receptor cluster dispersal and formation. J Cell Biol. 1998;141:1613-24 pubmed
	Feng G, Steinbach J, Sanes J. Rapsyn clusters neuronal acetylcholine receptors but is inessential for formation of an interneuronal cholinergic synapse. J Neurosci. 1998;18:4166-76 pubmed
	Cartaud A, Coutant S, Petrucci T, Cartaud J. Evidence for in situ and in vitro association between beta-dystroglycan and the subsynaptic 43K rapsyn protein. Consequence for acetylcholine receptor clustering at the synapse. J Biol Chem. 1998;273:11321-6 pubmed
	Meier T, Hauser D, Chiquet M, Landmann L, Ruegg M, Brenner H. Neural agrin induces ectopic postsynaptic specializations in innervated muscle fibers. J Neurosci. 1997;17:6534-44 pubmed

product information

Product Type :

Antibody

Product Name :

RAPSN Monoclonal Antibody (1234)

Catalog # :

MA1-746

Quantity :

100 ug

Price :

US 451.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Amphibian, Chicken, Fish, Mouse, Rat

Applications :

Immunocytochemistry: 2 ug/mL, Western Blot: 0.5 ug/mL

Species :

Amphibian, Chicken, Fish, Mouse, Rat

Clone :

1234

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen :

Whole purified rapsyn from Torpedo californica electric organ postsynaptic membrane.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 ug/mL, Western Blot: 0.5 ug/mL

Aliases :

43 kD receptor-associated protein of the synapse; 43 kda postsynaptic protein; 43 kDa receptor-associated protein of the synapse; 43kDa; 43kDa acetylcholine receptor-associated protein; acetylcholine receptor-associated 43 kda protein; AChR associated protein at synapses; acetylcholine receptor associated protein at synapses; 43kDa protein; likely to cluster nicotinic AChRs; CMS11; CMS1D; CMS1E; CMS4C; FADS; MGC3597; Nraps; Raps; Rapsn; rapsyn; receptor associated protein of the synapse; receptor-associated protein of the synapse; receptor-associated protein of the synapse, 43 kDa; receptor-associated protein of the synapse, 43kD; RING finger protein 205; RNF205; twitch once; two

more info or order :

Invitrogen product webpage