Epstein Barr Virus VCA Monoclonal Antibody (B21G) | Invitrogen MA1-7274 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Epstein Barr Virus VCA Monoclonal Antibody (B21G)

catalog :

MA1-7274

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

B21G

application :

immunocytochemistry

citations: 1

Reference
Tikhmyanova N, Tutton S, Martin K, Lu F, Kossenkov A, Paparoidamis N, et al. Small molecule perturbation of the CAND1-Cullin1-ubiquitin cycle stabilizes p53 and triggers Epstein-Barr virus reactivation. PLoS Pathog. 2017;13:e1006517 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Epstein Barr Virus VCA Monoclonal Antibody (B21G)

Catalog # :

MA1-7274

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Virus

Applications :

Immunocytochemistry: 1:10-1:50

Species :

Virus

Clone :

B21G

Isotype :

IgG1

Storage :

4 C

Description :

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.

Immunogen :

EBV VCA.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:10-1:50

Aliases :

EBV; EBV VCA