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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
FCAR (soluble) Monoclonal Antibody (MIP7c)
catalog :
MA1-72500
quantity :
100 ug
price :
US 414.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MIP7c
reactivity :
human
application :
flow cytometry, blocking or activating experiments
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; human; 10 ug/ml
Lecocq M, Detry B, Guisset A, Pilette C. Fc?RI-mediated inhibition of IL-12 production and priming by IFN-? of human monocytes and dendritic cells. J Immunol. 2013;190:2362-71 pubmed publisher
Temming A, Tammes Buirs M, Bentlage A, Treffers L, Feringa H, de Taeye S, et al. C-Reactive Protein Enhances IgG-Mediated Cellular Destruction Through IgG-Fc Receptors in vitro. Front Immunol. 2021;12:594773 pubmed publisher
Lu J, Marjon K, Mold C, Marnell L, Du Clos T, Sun P. Pentraxins and IgA share a binding hot-spot on FcαRI. Protein Sci. 2014;23:378-86 pubmed publisher
product information
Product Type :
Antibody
Product Name :
FCAR (soluble) Monoclonal Antibody (MIP7c)
Catalog # :
MA1-72500
Quantity :
100 ug
Price :
US 414.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1:100
Species :
Human
Clone :
MIP7c
Isotype :
IgG1
Storage :
Maintain refrigerated at 2-8 C for up to 1 month. For long term storage store at -20 C
Description :
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen :
Recombinant soluble CD89.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100
Aliases :
CD89; CTB-61M7.2; Fc alpha receptor; Fc fragment of IgA receptor; Fc fragment of IgA, receptor for; FcalphaRI; FCAR; IgA Fc receptor; immunoglobulin A Fc receptor; immunoglobulin A Fc receptor transcript variant 1; immunoglobulin A Fc receptor transcript variant 3; immunoglobulin A Fc receptor transcript variant 7; immunoglobulin A Fc receptor transcript variant 9; immunoglobulin A Fc receptor transcript variant deltaEC1; immunoglobulin A Fc receptor transcript variant deltaEC1 delta TM/C; immunoglobulin alpha Fc receptor
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA