This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
HIV1 Rev Group M Monoclonal Antibody (10)
catalog :
MA1-71514
quantity :
100 ug
price :
US 480.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10

The same clone is also sold as:
reactivity :
Human immunodeficiency virus 1
application :
western blot, ELISA
product information
Product Type :
Antibody
Product Name :
HIV1 Rev Group M Monoclonal Antibody (10)
Catalog # :
MA1-71514
Quantity :
100 ug
Price :
US 480.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Virus
Applications :
ELISA: 0.25-0.5 ug/mL, Western Blot: 2 ug/mL
Species :
Virus
Clone :
10
Isotype :
IgG1
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The HIV-1 Rev (regulator of expression of virion) protein is essential for the replication of HIV-1, especially in group M, which is the predominant and most widespread group of HIV-1 responsible for the global HIV epidemic. The Rev protein is encoded by the rev gene and plays a critical role in the nuclear export of unspliced and singly spliced viral mRNAs, which is crucial for the expression of structural proteins and the production of new virions. Structurally, Rev consists of an arginine-rich motif that allows it to bind to the Rev Response Element (RRE) within the viral RNA. This interaction facilitates the recruitment of the nuclear export receptor CRM1, which, along with other cofactors, translocates the RNA out of the nucleus. Functional disruption of Rev or its interaction with RRE significantly impedes HIV-1 replication, making these interactions potential targets for antiretroviral therapies.
Immunogen :
Recombinant Rev protein of HIV-1 BRV purified from E. coli
Format :
Liquid
Applications w/Dilutions :
ELISA: 0.25-0.5 ug/mL, Western Blot: 2 ug/mL
Aliases :
HIV group M; HIV-1 Rev
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA