product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5)
catalog :
MA1-70099
quantity :
250 ug
price :
US 470.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
RB6-8C5
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 238
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:50; fig 4b
Kumagai Y, Futoh Y, Miyato H, Ohzawa H, Yamaguchi H, Saito S, et al. Effect of Systemic or Intraperitoneal Administration of Anti-PD-1 Antibody for Peritoneal Metastases from Gastric Cancer. In Vivo. 2022;36:1126-1135 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3
Flamini S, Sergeev P, Viana de Barros Z, Mello T, Biagioli M, Paglialunga M, et al. Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment. Cell Death Dis. 2021;12:421 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4e
Cervantes P, Martorelli Di Genova B, Erazo Flores B, Knoll L. RIPK3 Facilitates Host Resistance to Oral Toxoplasma gondii Infection. Infect Immun. 2021;89: pubmed publisher
  • flow cytometry; mouse
Park B, Shin M, Kim J, Park G, Ryu Y, Lee J, et al. Ectopic Expression of Human Thymosin β4 Confers Resistance to Legionella pneumophila during Pulmonary and Systemic Infection in Mice. Infect Immun. 2021;89: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...
Ricci B, Tycksen E, Celik H, Belle J, Fontana F, Civitelli R, et al. Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...
Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 3c
Azcutia V, Kelm M, Luissint A, Boerner K, Flemming S, Quirós M, et al. Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo. Mucosal Immunol. 2020;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Tizian C, Lahmann A, Hölsken O, Cosovanu C, Kofoed Branzk M, Heinrich F, et al. c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3c
Mei Y, Wang Z, Zhang Y, Wan T, Xue J, He W, et al. FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Ameliorates DSS-Induced Colitis Against Oxidative Stress by Activating Nrf2/HO-1 Pathway. Front Immunol. 2019;10:2969 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig e1a, e1c
Vagnozzi R, Maillet M, Sargent M, Khalil H, Johansen A, Schwanekamp J, et al. An acute immune response underlies the benefit of cardiac stem cell therapy. Nature. 2020;577:405-409 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s19c
Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al. Spatiotemporal immune zonation of the human kidney. Science. 2019;365:1461-1466 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Zhang J, Supakorndej T, Krambs J, Rao M, Abou Ezzi G, Ye R, et al. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest. 2019;129:2920-2931 pubmed publisher
  • flow cytometry; mouse; 1:1000; loading ...; fig e2j, 4g
Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4f
Lee Y, Ju J, Shon W, Oh S, Min C, Kang M, et al. Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD. Immune Netw. 2018;18:e44 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Gubernatorova E, Gorshkova E, Namakanova O, Zvartsev R, Hidalgo J, Drutskaya M, et al. Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation. Front Immunol. 2018;9:2718 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Humblet Baron S, Barber J, Roca C, Lenaerts A, Koni P, Liston A. Murine myeloproliferative disorder as a consequence of impaired collaboration between dendritic cells and CD4 T cells. Blood. 2018;: pubmed publisher
  • flow cytometry; mouse; 1:75; loading ...; fig 3a
Kiang L, Ross B, Yao J, Shanmugam S, Andrews C, Hansen S, et al. Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment. Invest Ophthalmol Vis Sci. 2018;59:3767-3778 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2e
Kim Y, Lee M, Gu H, Kim J, Jeong S, Yeo S, et al. HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice. Dis Model Mech. 2018;11: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1e
Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, et al. An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion. Cell Stem Cell. 2018;22:879-892.e6 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Takamori A, Nambu A, Sato K, Yamaguchi S, Matsuda K, Numata T, et al. IL-31 is crucial for induction of pruritus, but not inflammation, in contact hypersensitivity. Sci Rep. 2018;8:6639 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 8b
Westhorpe C, Norman M, Hall P, Snelgrove S, Finsterbusch M, Li A, et al. Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes. Nat Commun. 2018;9:747 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Supramaniam A, Liu X, Ferro V, Herrero L. Prophylactic Antiheparanase Activity by PG545 Is Antiviral In Vitro and Protects against Ross River Virus Disease in Mice. Antimicrob Agents Chemother. 2018;62: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5
Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, et al. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018;9:75 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d
Guarnerio J, Mendez L, Asada N, Menon A, Fung J, Berry K, et al. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nat Commun. 2018;9:66 pubmed publisher
  • flow cytometry; human; loading ...; fig s26e
Gopalakrishnan V, Spencer C, Nezi L, Reuben A, Andrews M, Karpinets T, et al. Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science. 2018;359:97-103 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3
  • immunohistochemistry; mouse; loading ...; fig 5a
Sharif S, Nakatani Y, Wise L, Corbett M, Real N, Stuart G, et al. A Broad-Spectrum Chemokine-Binding Protein of Bovine Papular Stomatitis Virus Inhibits Neutrophil and Monocyte Infiltration in Inflammatory and Wound Models of Mouse Skin. PLoS ONE. 2016;11:e0168007 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 3
Bieber K, Witte M, Sun S, Hundt J, Kalies K, Dräger S, et al. T cells mediate autoantibody-induced cutaneous inflammation and blistering in epidermolysis bullosa acquisita. Sci Rep. 2016;6:38357 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
  • immunohistochemistry; mouse; 1:500; loading ...; fig 3c
Song Z, Li Z, Li D, Fang W, Liu H, Yang D, et al. Seminal plasma induces inflammation in the uterus through the ?? T/IL-17 pathway. Sci Rep. 2016;6:25118 pubmed publisher
  • flow cytometry; mouse; fig s2e
Alam M, Gaida M, Bergmann F, Lasitschka F, Giese T, Giese N, et al. Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression. Nat Med. 2015;21:1337-43 pubmed publisher
  • flow cytometry; mouse; fig 2
Ke F, Bouillet P, Kaufmann T, Strasser A, Kerr J, Voss A. Consequences of the combined loss of BOK and BAK or BOK and BAX. Cell Death Dis. 2013;4:e650 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 1
Kim M, Kang S, Park J, Yanagisawa M, Kim C. Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice. Gastroenterology. 2013;145:396-406.e1-10 pubmed publisher
  • immunohistochemistry; mouse; 1:200
  • western blot; mouse; 1:500
Xie P, Zhang W, Yuan S, Chen Z, Yang Q, Yuan D, et al. Suppression of experimental choroidal neovascularization by curcumin in mice. PLoS ONE. 2012;7:e53329 pubmed publisher
  • flow cytometry; human
Botelho F, Bauer C, Finch D, Nikota J, Zavitz C, Kelly A, et al. IL-1?/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice. PLoS ONE. 2011;6:e28457 pubmed publisher
  • flow cytometry; mouse
Horman S, Velu C, Chaubey A, Bourdeau T, Zhu J, Paul W, et al. Gfi1 integrates progenitor versus granulocytic transcriptional programming. Blood. 2009;113:5466-75 pubmed publisher
  • flow cytometry; mouse; fig 1
Culshaw S, Millington O, Brewer J, McInnes I. Murine neutrophils present Class II restricted antigen. Immunol Lett. 2008;118:49-54 pubmed publisher
  • immunohistochemistry; mouse
Wanasen N, Xin L, Soong L. Pathogenic role of B cells and antibodies in murine Leishmania amazonensis infection. Int J Parasitol. 2008;38:417-29 pubmed
  • flow cytometry; mouse; fig 1
Chang S, Wang K, Lu Y, Yang L, Chen W, Lin Y, et al. Characterization of early gamma interferon (IFN-gamma) expression during murine listeriosis: identification of NK1.1+ CD11c+ cells as the primary IFN-gamma-expressing cells. Infect Immun. 2007;75:1167-76 pubmed
  • immunohistochemistry - frozen section; mouse; fig 2
HogenEsch H, Dunham A, Seymour R, Renninger M, Sundberg J. Expression of chitinase-like proteins in the skin of chronic proliferative dermatitis (cpdm/cpdm) mice. Exp Dermatol. 2006;15:808-14 pubmed
  • flow cytometry; mouse
Grisaru D, Pick M, Perry C, Sklan E, Almog R, Goldberg I, et al. Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses. J Immunol. 2006;176:27-35 pubmed
  • flow cytometry; mouse
Gupta R, Karpatkin S, Basch R. Hematopoiesis and stem cell renewal in long-term bone marrow cultures containing catalase. Blood. 2006;107:1837-46 pubmed
  • flow cytometry; mouse
Lu M, Tayu R, Ikawa T, Masuda K, Matsumoto I, Mugishima H, et al. The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors. J Immunol. 2005;175:5848-56 pubmed
  • flow cytometry; mouse; fig 3
Noel J, Guo X, Wells Byrum D, Schwemberger S, Caldwell C, Ogle C. Effect of thermal injury on splenic myelopoiesis. Shock. 2005;23:115-22 pubmed
  • flow cytometry; mouse
Prockop S, Petrie H. Regulation of thymus size by competition for stromal niches among early T cell progenitors. J Immunol. 2004;173:1604-11 pubmed
  • flow cytometry; mouse
Smith P, Walsh C, Mangan N, Fallon R, Sayers J, McKenzie A, et al. Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages. J Immunol. 2004;173:1240-8 pubmed
  • flow cytometry; mouse; fig 4
Yuan Y, Shen H, Franklin D, Scadden D, Cheng T. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat Cell Biol. 2004;6:436-42 pubmed
  • flow cytometry; mouse; fig 6
  • flow cytometry; human; fig 6
de Haas C, Veldkamp K, Peschel A, Weerkamp F, Van Wamel W, Heezius E, et al. Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent. J Exp Med. 2004;199:687-95 pubmed
  • flow cytometry; mouse
Morin J, Faideau B, Gagnerault M, Lepault F, Boitard C, Boudaly S. Passive transfer of flt-3L-derived dendritic cells delays diabetes development in NOD mice and associates with early production of interleukin (IL)-4 and IL-10 in the spleen of recipient mice. Clin Exp Immunol. 2003;134:388-95 pubmed
  • flow cytometry; mouse; fig 2
Power U, Plotnicky H, Blaecke A, Nguyen T. The immunogenicity, protective efficacy and safety of BBG2Na, a subunit respiratory syncytial virus (RSV) vaccine candidate, against RSV-B. Vaccine. 2003;22:168-76 pubmed
  • flow cytometry; mouse; fig 3
Morin J, Chimènes A, Boitard C, Berthier R, Boudaly S. Granulocyte-dendritic cell unbalance in the non-obese diabetic mice. Cell Immunol. 2003;223:13-25 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 5D
Brown C, Blaho V, Loiacono C. Susceptibility to experimental Lyme arthritis correlates with KC and monocyte chemoattractant protein-1 production in joints and requires neutrophil recruitment via CXCR2. J Immunol. 2003;171:893-901 pubmed
  • flow cytometry; mouse; fig 4
Lan F, Zeng D, Higuchi M, Higgins J, Strober S. Host conditioning with total lymphoid irradiation and antithymocyte globulin prevents graft-versus-host disease: the role of CD1-reactive natural killer T cells. Biol Blood Marrow Transplant. 2003;9:355-63 pubmed
  • flow cytometry; mouse; fig 1
Plotnicky H, Siegrist C, Aubry J, Bonnefoy J, Corvaia N, Nguyen T, et al. Enhanced pulmonary immunopathology following neonatal priming with formalin-inactivated respiratory syncytial virus but not with the BBG2NA vaccine candidate. Vaccine. 2003;21:2651-60 pubmed
  • flow cytometry; mouse; fig 8
Saio M, Radoja S, Marino M, Frey A. Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide. J Immunol. 2001;167:5583-93 pubmed
  • flow cytometry; mouse; fig 1, 2
Lan F, Zeng D, Higuchi M, Huie P, Higgins J, Strober S. Predominance of NK1.1+TCR alpha beta+ or DX5+TCR alpha beta+ T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: "natural suppressor" cells. J Immunol. 2001;167:2087-96 pubmed
  • immunohistochemistry; mouse; fig 4
Klinguer C, Beck A, de Lys P, Bussat M, Blaecke A, Derouet F, et al. Lipophilic quaternary ammonium salt acts as a mucosal adjuvant when co-administered by the nasal route with vaccine antigens. Vaccine. 2001;19:4236-44 pubmed
  • immunohistochemistry; mouse; fig 4
Goetsch L, Plotnicky Gilquin H, Aubry J, de Lys P, Haeuw J, Bonnefoy J, et al. BBG2Na an RSV subunit vaccine candidate intramuscularly injected to human confers protection against viral challenge after nasal immunization in mice. Vaccine. 2001;19:4036-42 pubmed
  • immunohistochemistry - frozen section; mouse
de Oca R, Buendia A, Del Rio L, Sanchez J, Salinas J, Navarro J. Polymorphonuclear neutrophils are necessary for the recruitment of CD8(+) T cells in the liver in a pregnant mouse model of Chlamydophila abortus (Chlamydia psittaci serotype 1) infection. Infect Immun. 2000;68:1746-51 pubmed
  • immunohistochemistry - frozen section; mouse; fig 2
Whalen M, Carlos T, Dixon C, Robichaud P, Clark R, Marion D, et al. Reduced brain edema after traumatic brain injury in mice deficient in P-selectin and intercellular adhesion molecule-1. J Leukoc Biol. 2000;67:160-8 pubmed
  • flow cytometry; mouse; tbl 4
Saitoh T, Morimoto K, Kumagai T, Tsuboi I, Aikawa S, Horie T. Comparison of erythropoietic response to androgen in young and old senescence accelerated mice. Mech Ageing Dev. 1999;109:125-39 pubmed
  • flow cytometry; mouse
Lee S, Wang Y, Milbrandt J. Unimpaired macrophage differentiation and activation in mice lacking the zinc finger transplantation factor NGFI-A (EGR1). Mol Cell Biol. 1996;16:4566-72 pubmed
  • flow cytometry; mouse; fig 7
  • immunoprecipitation; mouse
Lewinsohn D, Bargatze R, Butcher E. Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes. J Immunol. 1987;138:4313-21 pubmed
de Boer L, Vanes L, Melgrati S, Biggs O May J, Hayward D, Driscoll P, et al. T cell migration requires ion and water influx to regulate actin polymerization. Nat Commun. 2023;14:7844 pubmed publisher
Pizzato H, Wang Y, Wolfgang M, Finck B, Patti G, Bhattacharya D. Mitochondrial pyruvate metabolism and glutaminolysis toggle steady-state and emergency myelopoiesis. J Exp Med. 2023;220: pubmed publisher
Talwar D, Miller C, Grossmann J, Szyrwiel L, Schwecke T, Demichev V, et al. The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells. Nat Metab. 2023;5:660-676 pubmed publisher
Cioni B, Ratti S, Piva A, Tripodi I, Milani M, Menichetti F, et al. JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent Macrophage Polarization in Breast Cancer. Mol Cancer Res. 2023;21:614-627 pubmed publisher
Tsai C, Chuang Y, Li X, Yu Y, Tzeng S, Teoh S, et al. Immunoediting instructs tumor metabolic reprogramming to support immune evasion. Cell Metab. 2023;35:118-133.e7 pubmed publisher
Gros M, Segura E, Rookhuizen D, Baudon B, Heurtebise Chr xe9 tien S, Burgdorf N, et al. Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation. Cell Rep. 2022;40:111205 pubmed publisher
Hu L, Chen L, Xiao Z, Zheng X, Chen Y, Xian N, et al. Ablation of T cell-associated PD-1H enhances functionality and promotes adoptive immunotherapy. JCI Insight. 2021;: pubmed publisher
Qin Y, Li B, Arumugam S, Lu Q, Mankash S, Li J, et al. m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity. Cell Rep. 2021;37:109968 pubmed publisher
Waaler J, Mygland L, Tveita A, Strand M, Solberg N, Olsen P, et al. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Commun Biol. 2020;3:196 pubmed publisher
Park C, Kehrl J. An integrin/MFG-E8 shuttle loads HIV-1 viral-like particles onto follicular dendritic cells in mouse lymph node. elife. 2019;8: pubmed publisher
Owyong M, Chou J, van den Bijgaart R, Kong N, Efe G, Maynard C, et al. MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy. Life Sci Alliance. 2019;2: pubmed publisher
Nachmani D, Bothmer A, Grisendi S, Mele A, Bothmer D, Lee J, et al. Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita. Nat Genet. 2019;51:1518-1529 pubmed publisher
Yu T, Gan S, Zhu Q, Dai D, Li N, Wang H, et al. Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24. Nat Commun. 2019;10:4353 pubmed publisher
Abdel Nour M, Carneiro L, Downey J, Tsalikis J, Outlioua A, Prescott D, et al. The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling. Science. 2019;365: pubmed publisher
Ren C, Yuan Q, Braun M, Zhang X, Petri B, Zhang J, et al. Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment. Dev Cell. 2019;49:206-219.e7 pubmed publisher
Dharmaraj N, Piotrowski S, Huang C, Newton J, Golfman L, Hanoteau A, et al. Anti-tumor immunity induced by ectopic expression of viral antigens is transient and limited by immune escape. Oncoimmunology. 2019;8:e1568809 pubmed publisher
Srivastava S, Salter A, Liggitt D, Yechan Gunja S, Sarvothama M, Cooper K, et al. Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting. Cancer Cell. 2019;35:489-503.e8 pubmed publisher
Łyszkiewicz M, Winter S, Witzlau K, Föhse L, Brownlie R, Puchałka J, et al. miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity. PLoS Biol. 2019;17:e2006716 pubmed publisher
Esnault C, Rahmé R, Rice K, Berthier C, Gaillard C, Quentin S, et al. FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias. Blood. 2019;: pubmed publisher
Cheng W, Tsui Y, Ragusa S, Koelzer V, Mina M, Franco F, et al. Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle. Nat Immunol. 2019;20:206-217 pubmed publisher
Liu C, He H, Li X, Su M, Cao Y. Dynamic metrics-based biomarkers to predict responders to anti-PD-1 immunotherapy. Br J Cancer. 2019;120:346-355 pubmed publisher
Wei Y, Chhiba K, Zhang F, Ye X, Wang L, Zhang L, et al. Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice. Int J Mol Sci. 2018;20: pubmed publisher
Percin G, Eitler J, Kranz A, Fu J, Pollard J, Naumann R, et al. CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages. Nat Commun. 2018;9:5279 pubmed publisher
Zhang W, Li Q, Li D, Li J, Aki D, Liu Y. The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation. J Exp Med. 2018;215:3180-3193 pubmed publisher
Sharma D, Malik A, Guy C, Vogel P, Kanneganti T. TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy. J Clin Invest. 2019;129:150-162 pubmed publisher
Grigoryan A, Guidi N, Senger K, Liehr T, Soller K, Marka G, et al. LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells. Genome Biol. 2018;19:189 pubmed publisher
Hsu J, Dayaram T, Tovy A, De Braekeleer E, Jeong M, Wang F, et al. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy. Cell Stem Cell. 2018;23:700-713.e6 pubmed publisher
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Willetts L, Felix L, Jacobsen E, Puttagunta L, Condjella R, Zellner K, et al. Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice. Commun Biol. 2018;1:83 pubmed publisher
Masuda J, Umemura C, Yokozawa M, Yamauchi K, Seko T, Yamashita M, et al. Dietary Supplementation of Selenoneine-Containing Tuna Dark Muscle Extract Effectively Reduces Pathology of Experimental Colorectal Cancers in Mice. Nutrients. 2018;10: pubmed publisher
Luo H, Winkelmann E, Zhu S, Ru W, Mays E, Silvas J, et al. Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection. J Clin Invest. 2018;128:4980-4991 pubmed publisher
Lin C, Titchenell P, Keil J, Garcia Ocana A, Bolinger M, ABCOUWER S, et al. Inhibition of Atypical Protein Kinase C Reduces Inflammation-Induced Retinal Vascular Permeability. Am J Pathol. 2018;188:2392-2405 pubmed publisher
Wray Dutra M, Al Qureshah F, Metzler G, Oukka M, James R, Rawlings D. Activated PIK3CD drives innate B cell expansion yet limits B cell-intrinsic immune responses. J Exp Med. 2018;215:2485-2496 pubmed publisher
Rodríguez Baena F, Redondo García S, Peris Torres C, Martino Echarri E, Fernández Rodríguez R, Plaza Calonge M, et al. ADAMTS1 protease is required for a balanced immune cell repertoire and tumour inflammatory response. Sci Rep. 2018;8:13103 pubmed publisher
Lahvic J, Ammerman M, Li P, Blair M, Stillman E, Fast E, et al. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proc Natl Acad Sci U S A. 2018;115:9252-9257 pubmed publisher
Lee S, North K, Kim E, Jang E, Obeng E, Lu S, et al. Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations. Cancer Cell. 2018;34:225-241.e8 pubmed publisher
Szabady R, Louissaint C, Lubben A, Xie B, Reeksting S, Tuohy C, et al. Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis. J Clin Invest. 2018;128:4044-4056 pubmed publisher
Tartey S, Gurung P, Samir P, Burton A, Kanneganti T. Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses. J Immunol. 2018;201:1639-1644 pubmed publisher
Bohrer A, Tocheny C, Assmann M, Ganusov V, Mayer Barber K. Cutting Edge: IL-1R1 Mediates Host Resistance to Mycobacterium tuberculosis by Trans-Protection of Infected Cells. J Immunol. 2018;201:1645-1650 pubmed publisher
Bah I, Kumbhare A, Nguyen L, McCall C, El Gazzar M. IL-10 induces an immune repressor pathway in sepsis by promoting S100A9 nuclear localization and MDSC development. Cell Immunol. 2018;332:32-38 pubmed publisher
Kim H, Park M, Lee S, Park J, Lee H, Bae Y. Activation of formyl peptide receptor 2 by WKYMVm enhances emergency granulopoiesis through phospholipase C activity. BMB Rep. 2018;51:418-423 pubmed
Morales Hernández A, Martinat A, Chabot A, Kang G, McKinney Freeman S. Elevated Oxidative Stress Impairs Hematopoietic Progenitor Function in C57BL/6 Substrains. Stem Cell Reports. 2018;11:334-347 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5)
Catalog # :
MA1-70099
Quantity :
250 ug
Price :
US 470.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Rat
Reactivity :
Mouse
Applications :
Cytotoxicity Assay: Assay-dependent, Flow Cytometry: 1 ug/1 million cells, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent
Species :
Mouse
Clone :
RB6-8C5
Isotype :
IgG2b
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm. They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments. In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes, the most abundant of the granulocytes. Granulocytes or PMN are released from the bone marrow by the regulatory complement proteins.
Immunogen :
granulocytes of mouse origin
Format :
Liquid
Applications w/Dilutions :
Cytotoxicity Assay: Assay-dependent, Flow Cytometry: 1 ug/1 million cells, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent
Aliases :
AA682074; AA959465; Gr1; Gr-1; Granulocyte Marker; Ly6c; Ly-6C; Ly-6C.2; Ly6c1; Ly-6C1; Ly6c2; Ly-6C2; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6 complex, locus C2; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6C precursor (Ly-6C); lymphocyte antigen 6C1; Lymphocyte antigen 6C2; lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA