| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; mouse; loading ...; fig s1a
| Yue X, Yin J, Wang X, Heidecke H, Hackel A, Dong X, et al. Induced antibodies directed to the angiotensin receptor type 1 provoke skin and lung inflammation, dermal fibrosis and act species overarching. Ann Rheum Dis. 2022;81:1281-9 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:250; loading ...; fig 4a
| Tacke S, Chunder R, Schropp V, Urich E, Kuerten S. Effects of a Fully Humanized Type II Anti-CD20 Monoclonal Antibody on Peripheral and CNS B Cells in a Transgenic Mouse Model of Multiple Sclerosis. Int J Mol Sci. 2022;23: pubmed publisher |
- flow cytometry; mouse; 1:500; loading ...; fig 1d
| Rivas M, Meydan C, Chin C, Challman M, Kim D, Bhinder B, et al. Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation. Nat Immunol. 2021;22:240-253 pubmed publisher |
- flow cytometry; mouse; loading ...
| Myers D, Abram C, Wildes D, Belwafa A, Welsh A, Schulze C, et al. Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity. Front Immunol. 2020;11:576310 pubmed publisher |
- flow cytometry; mouse; 1:200; loading ...
| Ricci B, Tycksen E, Celik H, Belle J, Fontana F, Civitelli R, et al. Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics. elife. 2020;9: pubmed publisher |
- flow cytometry; mouse; loading ...
| Panda S, Wigerblad G, Jiang L, Jiménez Andrade Y, Iyer V, Shen Y, et al. IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints. Proc Natl Acad Sci U S A. 2020;117:3103-3113 pubmed publisher |
- flow cytometry; mouse; 1:100; loading ...; fig e1a
| Vagnozzi R, Maillet M, Sargent M, Khalil H, Johansen A, Schwanekamp J, et al. An acute immune response underlies the benefit of cardiac stem cell therapy. Nature. 2020;577:405-409 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 3d
| Kotov J, Kotov D, Linehan J, Bardwell V, Gearhart M, Jenkins M. BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors. J Exp Med. 2019;216:1450-1464 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s1a
| Zhang J, Supakorndej T, Krambs J, Rao M, Abou Ezzi G, Ye R, et al. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest. 2019;129:2920-2931 pubmed publisher |
- flow cytometry; mouse; 1:400; loading ...; fig e2j, 4g
| Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 6b
| Marcandalli J, Fiala B, Ols S, Perotti M, De van der Schueren W, Snijder J, et al. Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus. Cell. 2019;176:1420-1431.e17 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 1c
| Rowe R, Lummertz da Rocha E, Sousa P, Missios P, Morse M, Marion W, et al. The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia. J Exp Med. 2019;216:527-538 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 1e
| Percin G, Eitler J, Kranz A, Fu J, Pollard J, Naumann R, et al. CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages. Nat Commun. 2018;9:5279 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s3b
| Nayar S, Campos J, Smith C, Iannizzotto V, Gardner D, Colafrancesco S, et al. Phosphatidylinositol 3-kinase delta pathway: a novel therapeutic target for Sjögren's syndrome. Ann Rheum Dis. 2019;78:249-260 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 5i
| Grigoryan A, Guidi N, Senger K, Liehr T, Soller K, Marka G, et al. LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells. Genome Biol. 2018;19:189 pubmed publisher |
- flow cytometry; mouse; loading ...; fig ev2c
| Er J, Koean R, Ding J. Loss of T-bet confers survival advantage to influenza-bacterial superinfection. EMBO J. 2019;38: pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 2e
| Bahmani B, Uehara M, Jiang L, Ordikhani F, Banouni N, Ichimura T, et al. Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival. J Clin Invest. 2018;128:4770-4786 pubmed publisher |
- flow cytometry; mouse; fig 6c
| Stephens J, Bailey J, Hang H, Rittell V, Dietrich M, Mynatt R, et al. Adipose Tissue Dysfunction Occurs Independently of Obesity in Adipocyte-Specific Oncostatin Receptor Knockout Mice. Obesity (Silver Spring). 2018;26:1439-1447 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 1c
| Cao A, Alluqmani N, Buhari F, Wasim L, Smith L, Quaile A, et al. Galectin-9 binds IgM-BCR to regulate B cell signaling. Nat Commun. 2018;9:3288 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 1c
| Webster B, Werneke S, Zafirova B, This S, Coléon S, Decembre E, et al. Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses. elife. 2018;7: pubmed publisher |
- flow cytometry; mouse; loading ...; fig s1e
| Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, et al. An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion. Cell Stem Cell. 2018;22:879-892.e6 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s5d
| Donaldson G, Ladinsky M, Yu K, Sanders J, Yoo B, Chou W, et al. Gut microbiota utilize immunoglobulin A for mucosal colonization. Science. 2018;360:795-800 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 1a
| Georgiev H, Ravens I, Papadogianni G, Halle S, Malissen B, Loots G, et al. Shared and Unique Features Distinguishing Follicular T Helper and Regulatory Cells of Peripheral Lymph Node and Peyer's Patches. Front Immunol. 2018;9:714 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 3e
| Harker J, Wong K, Dallari S, Bao P, Dolgoter A, Jo Y, et al. Interleukin-27R Signaling Mediates Early Viral Containment and Impacts Innate and Adaptive Immunity after Chronic Lymphocytic Choriomeningitis Virus Infection. J Virol. 2018;92: pubmed publisher |
- flow cytometry; mouse; loading ...; fig s1a
| Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine T, et al. Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression. J Clin Invest. 2018;128:2487-2499 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s3
| Safya H, Mellouk A, Legrand J, Le Gall S, Benbijja M, Kanellopoulos Langevin C, et al. Variations in Cellular Responses of Mouse T Cells to Adenosine-5'-Triphosphate Stimulation Do Not Depend on P2X7 Receptor Expression Levels but on Their Activation and Differentiation Stage. Front Immunol. 2018;9:360 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 1a
| Bröker K, Figge J, Magnusen A, Manz R, Köhl J, Karsten C. A Novel Role for C5a in B-1 Cell Homeostasis. Front Immunol. 2018;9:258 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 1a
- flow cytometry; mouse; loading ...; fig 5b
| Nadafi R, Koning J, Veninga H, Stachtea X, Konijn T, Zwiers A, et al. Dendritic Cell Migration to Skin-Draining Lymph Nodes Is Controlled by Dermatan Sulfate and Determines Adaptive Immunity Magnitude. Front Immunol. 2018;9:206 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 4b
| Kanayama M, Kato Y, Tsuji T, Konoeda Y, Hashimoto A, Kanauchi O, et al. Enhancement of immunomodulative effect of lactic acid bacteria on plasmacytoid dendritic cells with sucrose palmitate. Sci Rep. 2018;8:3147 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 2d
| Guarnerio J, Mendez L, Asada N, Menon A, Fung J, Berry K, et al. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nat Commun. 2018;9:66 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 3b
| Medaglia C, Giladi A, Stoler Barak L, De Giovanni M, Salame T, Biram A, et al. Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq. Science. 2017;358:1622-1626 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig s3a
| Kortlever R, Sodir N, Wilson C, Burkhart D, Pellegrinet L, Brown Swigart L, et al. Myc Cooperates with Ras by Programming Inflammation and Immune Suppression. Cell. 2017;171:1301-1315.e14 pubmed publisher |
- flow cytometry; human; loading ...; fig s2
| Schwartz J, Ma J, Lamprecht T, Walsh M, Wang S, Bryant V, et al. The genomic landscape of pediatric myelodysplastic syndromes. Nat Commun. 2017;8:1557 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 7c
| Minguet S, Kläsener K, Schaffer A, Fiala G, Osteso Ibanez T, Raute K, et al. Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance. Nat Immunol. 2017;18:1150-1159 pubmed publisher |
| van der Vlugt L, Obieglo K, Ozir Fazalalikhan A, Sparwasser T, Haeberlein S, Smits H. Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function. Int J Parasitol. 2017;47:545-554 pubmed publisher |
- flow cytometry; mouse; 1:100; loading ...; fig 1a
| Katerndahl C, Heltemes Harris L, Willette M, Henzler C, Frietze S, Yang R, et al. Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival. Nat Immunol. 2017;18:694-704 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s2
| Yang J, Tanaka Y, Seay M, Li Z, Jin J, Garmire L, et al. Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors. Nucleic Acids Res. 2017;45:1281-1296 pubmed publisher |
- flow cytometry; mouse; loading ...; fig st1
| Strawbridge R, Hilding A, Silveira A, Osterholm C, Sennblad B, McLeod O, et al. Soluble CD93 Is Involved in Metabolic Dysregulation but Does Not Influence Carotid Intima-Media Thickness. Diabetes. 2016;65:2888-99 pubmed publisher |
- flow cytometry; mouse; fig 1A
| Veinotte L, Gebremeskel S, Johnston B. CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFN? production and tumor control. Oncoimmunology. 2016;5:e1160979 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s1c
| De Grove K, Provoost S, Hendriks R, McKenzie A, Seys L, Kumar S, et al. Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses. J Allergy Clin Immunol. 2017;139:246-257.e4 pubmed publisher |
- flow cytometry; mouse; loading ...
| Seehus C, Kaye J. In vitro Differentiation of Murine Innate Lymphoid Cells from Common Lymphoid Progenitor Cells. Bio Protoc. 2016;6: pubmed |
- flow cytometry; mouse; loading ...; fig 1a
| Galloway A, Saveliev A, Łukasiak S, Hodson D, Bolland D, Balmanno K, et al. RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence. Science. 2016;352:453-9 pubmed publisher |
- flow cytometry; mouse; loading ...
| Zhong C, Cui K, Wilhelm C, Hu G, Mao K, Belkaid Y, et al. Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment. Nat Immunol. 2016;17:169-78 pubmed publisher |
- flow cytometry; human; loading ...; fig s1a
| Schulz A, Mälzer J, Domingo C, Jürchott K, Grützkau A, Babel N, et al. Low Thymic Activity and Dendritic Cell Numbers Are Associated with the Immune Response to Primary Viral Infection in Elderly Humans. J Immunol. 2015;195:4699-711 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:200; fig 6
| Böttcher J, Beyer M, Meissner F, Abdullah Z, Sander J, Höchst B, et al. Functional classification of memory CD8(+) T cells by CX3CR1 expression. Nat Commun. 2015;6:8306 pubmed publisher |
| Sin S, Kim Y, Eason A, Dittmer D. KSHV Latency Locus Cooperates with Myc to Drive Lymphoma in Mice. PLoS Pathog. 2015;11:e1005135 pubmed publisher |
- immunohistochemistry; mouse; fig 1
| Donaldson D, Else K, Mabbott N. The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis. J Virol. 2015;89:9532-47 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 3c
| Sei J, Haskett S, Kaminsky L, Lin E, Truckenmiller M, Bellone C, et al. Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation. PLoS Pathog. 2015;11:e1004941 pubmed publisher |
- flow cytometry; mouse; fig s3
| Vettermann C, Timblin G, Lim V, Lai E, Schlissel M. The proximal J kappa germline-transcript promoter facilitates receptor editing through control of ordered recombination. PLoS ONE. 2015;10:e0113824 pubmed publisher |
| Schollaert K, Stephens M, Gray J, Fulkerson P. Generation of eosinophils from cryopreserved murine bone marrow cells. PLoS ONE. 2014;9:e116141 pubmed publisher |
- flow cytometry; mouse; fig 5
| Morales D, Monte K, Sun L, Struckhoff J, Agapov E, Holtzman M, et al. Novel mode of ISG15-mediated protection against influenza A virus and Sendai virus in mice. J Virol. 2015;89:337-49 pubmed publisher |
- flow cytometry; mouse
- immunohistochemistry; mouse; fig 1
| Donaldson D, Bradford B, Artis D, Mabbott N. Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23. Mucosal Immunol. 2015;8:582-95 pubmed publisher |
| Smolarchuk C, Zhu L, Chan W, Anderson C. T cells generated in the absence of a thoracic thymus fail to establish homeostasis. Eur J Immunol. 2014;44:2263-73 pubmed publisher |
- flow cytometry; mouse; fig 2
| Fuertbauer E, Zaujec J, Uhrin P, Raab I, Weber M, Schachner H, et al. Thymic medullar conduits-associated podoplanin promotes natural regulatory T cells. Immunol Lett. 2013;154:31-41 pubmed publisher |
- flow cytometry; mouse; fig 2
| Ke F, Bouillet P, Kaufmann T, Strasser A, Kerr J, Voss A. Consequences of the combined loss of BOK and BAK or BOK and BAX. Cell Death Dis. 2013;4:e650 pubmed publisher |
- immunohistochemistry - frozen section; mouse; fig 7j
| Kobayashi A, Donaldson D, Erridge C, Kanaya T, Williams I, Ohno H, et al. The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice. Mucosal Immunol. 2013;6:1027-37 pubmed publisher |
- immunohistochemistry - frozen section; mouse
| Chevrier S, Genton C, Malissen B, Malissen M, Acha Orbea H. Dominant Role of CD80-CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LAT(Y136F) CD4(+) T Cells. Front Immunol. 2012;3:27 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; fig 2
| Nishino T, Ashida R, Obata Y, Furusu A, Abe K, Miyazaki M, et al. Involvement of lymphocyte infiltration in the progression of mouse peritoneal fibrosis model. Ren Fail. 2012;34:760-6 pubmed publisher |
| Randall K, Chan S, Ma C, Fung I, Mei Y, Yabas M, et al. DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice. J Exp Med. 2011;208:2305-20 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; fig 4
| Bosticardo M, Draghici E, Schena F, Sauer A, Fontana E, Castiello M, et al. Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome. J Allergy Clin Immunol. 2011;127:1376-84.e5 pubmed publisher |
| Siegemund S, Hartl A, von Buttlar H, Dautel F, Raue R, Freudenberg M, et al. Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis. J Virol. 2009;83:9411-22 pubmed publisher |
| Horman S, Velu C, Chaubey A, Bourdeau T, Zhu J, Paul W, et al. Gfi1 integrates progenitor versus granulocytic transcriptional programming. Blood. 2009;113:5466-75 pubmed publisher |
- flow cytometry; mouse; fig 2, 4
| Rogers N, Lees M, Gabriel L, Maniati E, Rose S, Potter P, et al. A defect in Marco expression contributes to systemic lupus erythematosus development via failure to clear apoptotic cells. J Immunol. 2009;182:1982-90 pubmed publisher |
| Muller U, Stenzel W, Kohler G, Polte T, Blessing M, Mann A, et al. A gene-dosage effect for interleukin-4 receptor alpha-chain expression has an impact on Th2-mediated allergic inflammation during bronchopulmonary mycosis. J Infect Dis. 2008;198:1714-21 pubmed publisher |
- flow cytometry; mouse; fig 4
| Wells J, Cowled C, Farzaneh F, Noble A. Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity. J Immunol. 2008;181:3422-31 pubmed |
- immunohistochemistry - frozen section; mouse
| Bahjat F, Pine P, Reitsma A, Cassafer G, Baluom M, Grillo S, et al. An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus. Arthritis Rheum. 2008;58:1433-44 pubmed publisher |
| Allard E, Hardy M, Leignadier J, Marquis M, Rooney J, Lehoux D, et al. Overexpression of IL-21 promotes massive CD8+ memory T cell accumulation. Eur J Immunol. 2007;37:3069-77 pubmed |
| Muller U, Stenzel W, Kohler G, Werner C, Polte T, Hansen G, et al. IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans. J Immunol. 2007;179:5367-77 pubmed |
- flow cytometry; mouse
- immunohistochemistry; mouse
| Carlsson F, Hjelm F, Conrad D, Heyman B. IgE enhances specific antibody and T-cell responses in mice overexpressing CD23. Scand J Immunol. 2007;66:261-70 pubmed |
- flow cytometry; mouse; fig 1
| Yanaba K, Hamaguchi Y, Venturi G, Steeber D, St Clair E, Tedder T. B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity. J Immunol. 2007;179:1369-80 pubmed |
| Hayakawa I, Tedder T, Zhuang Y. B-lymphocyte depletion ameliorates Sjögren's syndrome in Id3 knockout mice. Immunology. 2007;122:73-9 pubmed |
- flow cytometry; mouse; fig 6
| Kaminski D, Stavnezer J. Antibody class switching differs among SJL, C57BL/6 and 129 mice. Int Immunol. 2007;19:545-56 pubmed |
- immunohistochemistry - frozen section; mouse
| Schwickert T, Lindquist R, Shakhar G, Livshits G, Skokos D, Kosco Vilbois M, et al. In vivo imaging of germinal centres reveals a dynamic open structure. Nature. 2007;446:83-7 pubmed |
- flow cytometry; mouse; fig 1
| Kaminski D, Stavnezer J. Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells. J Immunol. 2006;177:6025-9 pubmed |
| Silver K, Ferry H, Crockford T, Cornall R. TLR4, TLR9 and MyD88 are not required for the positive selection of autoreactive B cells into the primary repertoire. Eur J Immunol. 2006;36:1404-12 pubmed |
| Otten L, LeibundGut Landmann S, Huarte J, Kos Braun I, Lavanchy C, Barras E, et al. Revisiting the specificity of the MHC class II transactivator CIITA in vivo. Eur J Immunol. 2006;36:1548-58 pubmed |
| Fukatsu K, Sakamoto S, Hara E, Ueno C, Maeshima Y, Matsumoto I, et al. Gut ischemia-reperfusion affects gut mucosal immunity: a possible mechanism for infectious complications after severe surgical insults. Crit Care Med. 2006;34:182-7 pubmed |
- flow cytometry; mouse; fig 1
| Tsunoda I, Kuang L, Kobayashi Warren M, Fujinami R. Central nervous system pathology caused by autoreactive CD8+ T-cell clones following virus infection. J Virol. 2005;79:14640-6 pubmed |
- flow cytometry; mouse; fig 8
| Gupta R, Karpatkin S, Basch R. Hematopoiesis and stem cell renewal in long-term bone marrow cultures containing catalase. Blood. 2006;107:1837-46 pubmed |
- flow cytometry; mouse; fig 4
| Lu M, Tayu R, Ikawa T, Masuda K, Matsumoto I, Mugishima H, et al. The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors. J Immunol. 2005;175:5848-56 pubmed |
| Koyama K. Dendritic cell expansion occurs in mesenteric lymph nodes of B10.BR mice infected with the murine nematode parasite Trichuris muris. Parasitol Res. 2005;97:186-90 pubmed |
| Iwasaki H, Mizuno S, Mayfield R, Shigematsu H, Arinobu Y, Seed B, et al. Identification of eosinophil lineage-committed progenitors in the murine bone marrow. J Exp Med. 2005;201:1891-7 pubmed |
- flow cytometry; mouse; fig 1
| Iwasaki H, Somoza C, Shigematsu H, Duprez E, Iwasaki Arai J, Mizuno S, et al. Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation. Blood. 2005;106:1590-600 pubmed |
| Iseki M, Kubo Akashi C, Kwon S, Yamaguchi A, Takatsu K, Takaki S. APS, an adaptor molecule containing PH and SH2 domains, has a negative regulatory role in B cell proliferation. Biochem Biophys Res Commun. 2005;330:1005-13 pubmed |
| Growney J, Shigematsu H, Li Z, Lee B, Adelsperger J, Rowan R, et al. Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype. Blood. 2005;106:494-504 pubmed |
- immunohistochemistry - frozen section; mouse
- flow cytometry; mouse
| Hamaguchi Y, Uchida J, Cain D, Venturi G, Poe J, Haas K, et al. The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice. J Immunol. 2005;174:4389-99 pubmed |
- immunohistochemistry - paraffin section; human; 4 ug/ml; fig 2
- flow cytometry; human; fig 1
| Rodig S, Shahsafaei A, Li B, Dorfman D. The CD45 isoform B220 identifies select subsets of human B cells and B-cell lymphoproliferative disorders. Hum Pathol. 2005;36:51-7 pubmed |
- flow cytometry; mouse; fig 3
| Noel J, Guo X, Wells Byrum D, Schwemberger S, Caldwell C, Ogle C. Effect of thermal injury on splenic myelopoiesis. Shock. 2005;23:115-22 pubmed |
| Zheng S, Jiang J, Shen H, Chen Y. Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice. J Immunol. 2004;173:5652-8 pubmed |
- flow cytometry; mouse; fig 2
| Lian Z, Kikuchi K, Yang G, Ansari A, Ikehara S, Gershwin M. Expansion of bone marrow IFN-alpha-producing dendritic cells in New Zealand Black (NZB) mice: high level expression of TLR9 and secretion of IFN-alpha in NZB bone marrow. J Immunol. 2004;173:5283-9 pubmed |
- flow cytometry; mouse; fig 1B
| Herman A, Freeman G, Mathis D, Benoist C. CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J Exp Med. 2004;199:1479-89 pubmed |
- flow cytometry; mouse; fig 4
| Yuan Y, Shen H, Franklin D, Scadden D, Cheng T. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat Cell Biol. 2004;6:436-42 pubmed |
- flow cytometry; mouse; fig 2
| Iseki M, Kubo C, Kwon S, Yamaguchi A, Kataoka Y, Yoshida N, et al. Increased numbers of B-1 cells and enhanced responses against TI-2 antigen in mice lacking APS, an adaptor molecule containing PH and SH2 domains. Mol Cell Biol. 2004;24:2243-50 pubmed |
- immunohistochemistry - frozen section; mouse; 1:50; fig 4
| Rey J, Garin N, Spertini F, Corthesy B. Targeting of secretory IgA to Peyer's patch dendritic and T cells after transport by intestinal M cells. J Immunol. 2004;172:3026-33 pubmed |
- flow cytometry; mouse; fig 6
| Ishihara K, Sawa S, Ikushima H, Hirota S, Atsumi T, Kamimura D, et al. The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis. Int Immunol. 2004;16:455-65 pubmed |
- flow cytometry; mouse; fig 1
| Chen B, Cui X, Sempowski G, Domen J, Chao N. Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation. Blood. 2004;103:4344-52 pubmed |
- immunohistochemistry - frozen section; mouse
| Blasius A, Vermi W, Krug A, Facchetti F, Cella M, Colonna M. A cell-surface molecule selectively expressed on murine natural interferon-producing cells that blocks secretion of interferon-alpha. Blood. 2004;103:4201-6 pubmed |
| Morin J, Faideau B, Gagnerault M, Lepault F, Boitard C, Boudaly S. Passive transfer of flt-3L-derived dendritic cells delays diabetes development in NOD mice and associates with early production of interleukin (IL)-4 and IL-10 in the spleen of recipient mice. Clin Exp Immunol. 2003;134:388-95 pubmed |
- flow cytometry; mouse; fig 2
| Leider N, Melamed D. Differential c-Myc responsiveness to B cell receptor ligation in B cell-negative selection. J Immunol. 2003;171:2446-52 pubmed |
- flow cytometry; mouse; fig 1
| Germeraad W, Kawamoto H, Itoi M, Jiang Y, Amagai T, Katsura Y, et al. Development of thymic microenvironments in vitro is oxygen-dependent and requires permanent presence of T-cell progenitors. J Histochem Cytochem. 2003;51:1225-35 pubmed |
- flow cytometry; mouse; fig 3
| Morin J, Chimènes A, Boitard C, Berthier R, Boudaly S. Granulocyte-dendritic cell unbalance in the non-obese diabetic mice. Cell Immunol. 2003;223:13-25 pubmed |
| Richards M, Liu F, Iwasaki H, Akashi K, Link D. Pivotal role of granulocyte colony-stimulating factor in the development of progenitors in the common myeloid pathway. Blood. 2003;102:3562-8 pubmed |
| Reading P, Smith G. A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection. J Gen Virol. 2003;84:1973-83 pubmed |
| Koyama K. NK1.1+ cell depletion in vivo fails to prevent protection against infection with the murine nematode parasite Trichuris muris. Parasite Immunol. 2002;24:527-33 pubmed |
- flow cytometry; mouse; tbl 1
| Kawamoto H, Ohmura K, Fujimoto S, Lu M, Ikawa T, Katsura Y. Extensive proliferation of T cell lineage-restricted progenitors in the thymus: an essential process for clonal expression of diverse T cell receptor beta chains. Eur J Immunol. 2003;33:606-15 pubmed |
| Yamasaki M, Chujo H, Hirao A, Koyanagi N, Okamoto T, Tojo N, et al. Immunoglobulin and cytokine production from spleen lymphocytes is modulated in C57BL/6J mice by dietary cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid. J Nutr. 2003;133:784-8 pubmed |
- flow cytometry; mouse; fig 4
| Otten L, Tacchini Cottier F, Lohoff M, Annunziato F, Cosmi L, Scarpellino L, et al. Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes. J Immunol. 2003;170:1150-7 pubmed |
- flow cytometry; mouse; fig 4
| Kusunoki T, Sugai M, Katakai T, Omatsu Y, Iyoda T, Inaba K, et al. TH2 dominance and defective development of a CD8+ dendritic cell subset in Id2-deficient mice. J Allergy Clin Immunol. 2003;111:136-42 pubmed |
| Bleesing J, Fleisher T. Human B cells express a CD45 isoform that is similar to murine B220 and is downregulated with acquisition of the memory B-cell marker CD27. Cytometry B Clin Cytom. 2003;51:1-8 pubmed |
- flow cytometry; human; fig 1
| Bleesing J, Janik J, Fleisher T. Common expression of an unusual CD45 isoform on T cells from patients with large granular lymphocyte leukaemia and autoimmune lymphoproliferative syndrome. Br J Haematol. 2003;120:93-6 pubmed |
- flow cytometry; mouse; fig 2
| Cabatingan M, Schmidt M, Sen R, Woodland R. Naive B lymphocytes undergo homeostatic proliferation in response to B cell deficit. J Immunol. 2002;169:6795-805 pubmed |
| Stavitsky A, Xianli J. In vitro and in vivo regulation by macrophage migration inhibitory factor (MIF) of expression of MHC-II, costimulatory, adhesion, receptor, and cytokine molecules. Cell Immunol. 2002;217:95-104 pubmed |
- flow cytometry; mouse; fig 2
| Prasad S, Goodnow C. Cell-intrinsic effects of non-MHC NOD genes on dendritic cell generation in vivo. Int Immunol. 2002;14:677-84 pubmed |
| Chen B, Cui X, Sempowski G, Gooding M, Liu C, Haynes B, et al. A comparison of murine T-cell-depleted adult bone marrow and full-term fetal blood cells in hematopoietic engraftment and immune reconstitution. Blood. 2002;99:364-71 pubmed |
- immunohistochemistry - frozen section; mouse
| Schneider P, Takatsuka H, Wilson A, Mackay F, Tardivel A, Lens S, et al. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med. 2001;194:1691-7 pubmed |
- flow cytometry; mouse; fig 6
| Tourneur L, Malassagne B, Batteux F, Fabre M, Mistou S, Lallemand E, et al. Transgenic expression of CD95 ligand on thyroid follicular cells confers immune privilege upon thyroid allografts. J Immunol. 2001;167:1338-46 pubmed |
- flow cytometry; mouse; fig 2
| Roach D, Martin E, Bean A, Rennick D, Briscoe H, Britton W. Endogenous inhibition of antimycobacterial immunity by IL-10 varies between mycobacterial species. Scand J Immunol. 2001;54:163-70 pubmed |
- flow cytometry; mouse; fig 5
| Finke D, Baribaud F, Diggelmann H, Acha Orbea H. Extrafollicular plasmablast B cells play a key role in carrying retroviral infection to peripheral organs. J Immunol. 2001;166:6266-75 pubmed |
- immunocytochemistry; mouse; fig 7
| Attinger A, MacDonald H, Acha Orbea H. Lymphoid environment limits superantigen and antigen-induced T cell proliferation at high precursor frequency. Eur J Immunol. 2001;31:884-93 pubmed |
- blocking or activating experiments; mouse; fig 1
| Minagawa H, Yanagi Y. Latent herpes simplex virus-1 infection in SCID mice transferred with immune CD4+T cells: a new model for latency. Arch Virol. 2000;145:2259-72 pubmed |
- flow cytometry; mouse; fig 1
| Shimizu C, Kawamoto H, Yamashita M, Kimura M, Kondou E, Kaneko Y, et al. Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity. Int Immunol. 2001;13:105-17 pubmed |
- flow cytometry; mouse; fig 3
| Izeradjene K, Revillard J, Genestier L. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independent deletion of superantigen-reactive peripheral T cells. Int Immunol. 2001;13:85-93 pubmed |
- flow cytometry; mouse; tbl 1
| Cohen J, Saron M, Boyer O, Thomas Vaslin V, Bellier B, Lejeune L, et al. Preservation of graft-versus-infection effects after suicide gene therapy for prevention of graft-versus-host disease. Hum Gene Ther. 2000;11:2473-81 pubmed |
| Telega G, Baumgart D, Carding S. Uptake and presentation of antigen to T cells by primary colonic epithelial cells in normal and diseased states. Gastroenterology. 2000;119:1548-59 pubmed |
- flow cytometry; mouse; fig 7
| Bauman S, Nichols K, Murphy J. Dendritic cells in the induction of protective and nonprotective anticryptococcal cell-mediated immune responses. J Immunol. 2000;165:158-67 pubmed |
- flow cytometry; mouse; fig 1
| Wei C, Zeff R, Goldschneider I. Murine pro-B cells require IL-7 and its receptor complex to up-regulate IL-7R alpha, terminal deoxynucleotidyltransferase, and c mu expression. J Immunol. 2000;164:1961-70 pubmed |
| Tanneau G, Hibrand Saint Oyant L, Chevaleyre C, Salmon H. Differential recruitment of T- and IgA B-lymphocytes in the developing mammary gland in relation to homing receptors and vascular addressins. J Histochem Cytochem. 1999;47:1581-92 pubmed |
| Corcoran L, Tawfilis S, Barlow L. Generation of B lymphoma cell lines from knockout mice by transformation in vivo with an Emu-myc transgene. J Immunol Methods. 1999;228:131-8 pubmed |
| Pan L, Sato S, Frederick J, Sun X, Zhuang Y. Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene. Mol Cell Biol. 1999;19:5969-80 pubmed |
| Baribaud F, Shaw A, Scarpellino L, Diggelmann H, Acha Orbea H. Preferential binding of mouse mammary tumor virus to B lymphocytes. J Virol. 1999;73:7899-902 pubmed |
| Kawamoto H, Ohmura K, Fujimoto S, Katsura Y. Emergence of T cell progenitors without B cell or myeloid differentiation potential at the earliest stage of hematopoiesis in the murine fetal liver. J Immunol. 1999;162:2725-31 pubmed |
| Kretz Rommel A, Rubin R. Persistence of autoreactive T cell drive is required to elicit anti-chromatin antibodies in a murine model of drug-induced lupus. J Immunol. 1999;162:813-20 pubmed |
| Batteux F, Tourneur L, Trebeden H, Charreire J, Chiocchia G. Gene therapy of experimental autoimmune thyroiditis by in vivo administration of plasmid DNA coding for Fas ligand. J Immunol. 1999;162:603-8 pubmed |
| Ohta M, Sakai T, Saga Y, Aizawa S, Saito M. Suppression of hematopoietic activity in tenascin-C-deficient mice. Blood. 1998;91:4074-83 pubmed |
- flow cytometry; mouse; fig 4
| Contractor N, Bassiri H, Reya T, Park A, Baumgart D, Wasik M, et al. Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice. J Immunol. 1998;160:385-94 pubmed |
- flow cytometry; mouse; fig 2
| Humbert P, Corcoran L. oct-2 gene disruption eliminates the peritoneal B-1 lymphocyte lineage and attenuates B-2 cell maturation and function. J Immunol. 1997;159:5273-84 pubmed |
- flow cytometry; mouse; tbl 1
| Schuppe H, Kulig J, Lerchenmüller C, Becker D, Gleichmann E, Kind P. Contact hypersensitivity to disodium hexachloroplatinate in mice. Toxicol Lett. 1997;93:125-33 pubmed |
- flow cytometry; mouse; fig 3
| Tarlinton D, Corcoran L, Strasser A. Continued differentiation during B lymphopoiesis requires signals in addition to cell survival. Int Immunol. 1997;9:1481-94 pubmed |
| Zhang T, Kawakami K, Qureshi M, Okamura H, Kurimoto M, Saito A. Interleukin-12 (IL-12) and IL-18 synergistically induce the fungicidal activity of murine peritoneal exudate cells against Cryptococcus neoformans through production of gamma interferon by natural killer cells. Infect Immun. 1997;65:3594-9 pubmed |
- immunocytochemistry; mouse; 4 ug/ml; tbl 2
| Yamagami S, Isobe M, Yamagami H, Hori J, Tsuru T. Mechanism of concordant corneal xenograft rejection in mice: synergistic effects of anti-leukocyte function-associated antigen-1 monoclonal antibody and FK506. Transplantation. 1997;64:42-8 pubmed |
- flow cytometry; mouse; fig 1
| Melamed D, Kench J, Grabstein K, Rolink A, Nemazee D. A functional B cell receptor transgene allows efficient IL-7-independent maturation of B cell precursors. J Immunol. 1997;159:1233-9 pubmed |
| Hattori N, Kawamoto H, Katsura Y. Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells. J Exp Med. 1996;184:1901-8 pubmed |
- flow cytometry; mouse; fig 1
| Sumita S, Ozaki S, Okazaki T, Sobajima J, Nakao K. A vascular smooth muscle-specific CD4+ T cell line that induces pulmonary vasculitis in MRL-+/+ mice. Clin Exp Immunol. 1996;105:163-8 pubmed |
- immunoprecipitation; mouse
| Goodell M, Brose K, Paradis G, Conner A, Mulligan R. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med. 1996;183:1797-806 pubmed |
- flow cytometry; mouse; fig 3
| Salomon B, Lores P, Pioche C, Racz P, Jami J, Klatzmann D. Conditional ablation of dendritic cells in transgenic mice. J Immunol. 1994;152:537-48 pubmed |
| Longmore G, Pharr P, Lodish H. A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells. Mol Cell Biol. 1994;14:2266-77 pubmed |
- flow cytometry; mouse; fig 5
| Luo Y, Laning J, Devi S, Mak J, Schall T, Dorf M. Biologic activities of the murine beta-chemokine TCA3. J Immunol. 1994;153:4616-24 pubmed |
| Lepault F, Gagnerault M, Faveeuw C, Bazin H, Boitard C. Lack of L-selectin expression by cells transferring diabetes in NOD mice: insights into the mechanisms involved in diabetes prevention by Mel-14 antibody treatment. Eur J Immunol. 1995;25:1502-7 pubmed |
| Ohteki T, Iwamoto M, Izui S, MacDonald H. Reduced development of CD4-8-B220+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules. Eur J Immunol. 1995;25:37-41 pubmed |
- blocking or activating experiments; mouse; fig 2
- flow cytometry; mouse
| Domiati Saad R, Ogle E, Justement L. Administration of anti-CD45 mAb specific for a B cell-restricted epitope abrogates the B cell response to a T-dependent antigen in vivo. J Immunol. 1993;151:5936-47 pubmed |
- immunocytochemistry; mouse
| Ishida H, Hastings R, Kearney J, Howard M. Continuous anti-interleukin 10 antibody administration depletes mice of Ly-1 B cells but not conventional B cells. J Exp Med. 1992;175:1213-20 pubmed |
- flow cytometry; mouse; fig 9
| Brink R, Goodnow C, Crosbie J, Adams E, Eris J, Mason D, et al. Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen. J Exp Med. 1992;176:991-1005 pubmed |
| Salles G, Chen C, Reinherz E, Shipp M. CD10/NEP is expressed on Thy-1low B220+ murine B-cell progenitors and functions to regulate stromal cell-dependent lymphopoiesis. Blood. 1992;80:2021-9 pubmed |
| Talwar D, Miller C, Grossmann J, Szyrwiel L, Schwecke T, Demichev V, et al. The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells. Nat Metab. 2023;5:660-676 pubmed publisher |
| Singh S, Lee N, Pedroza D, Bado I, Hamor C, Zhang L, et al. Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer. Cancer Res. 2022;82:2281-2297 pubmed publisher |
| Schick M, Zhang L, Maurer S, Maurer H, Isaakaidis K, Schneider L, et al. Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma. Nat Commun. 2022;13:281 pubmed publisher |
| Florian M, Leins H, Gobs M, Han Y, Marka G, Soller K, et al. Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice. Aging Cell. 2020;:e13208 pubmed publisher |
| Tummers B, Mari L, Guy C, Heckmann B, Rodriguez D, Rühl S, et al. Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis. Immunity. 2020;52:994-1006.e8 pubmed publisher |
| Sodir N, Kortlever R, Barthet V, Campos T, Pellegrinet L, Kupczak S, et al. MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype. Cancer Discov. 2020;10:588-607 pubmed publisher |
| Goldstein J, Valido A, Lewandowski J, Walker R, Mills M, Messemer K, et al. Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus. Sci Rep. 2019;9:18613 pubmed publisher |
| Chen L, Strohmeier V, He Z, Deshpande M, Catalan Dibene J, Durum S, et al. Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23. Nat Commun. 2019;10:4517 pubmed publisher |
| Nachmani D, Bothmer A, Grisendi S, Mele A, Bothmer D, Lee J, et al. Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita. Nat Genet. 2019;51:1518-1529 pubmed publisher |
| Yu T, Gan S, Zhu Q, Dai D, Li N, Wang H, et al. Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24. Nat Commun. 2019;10:4353 pubmed publisher |
| Vacchio M, Ciucci T, Gao Y, Watanabe M, Balmaceno Criss M, McGinty M, et al. A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation. Immunity. 2019;51:465-478.e6 pubmed publisher |
| Ni G, Wang Y, Good D, Yuan J, Pan X, Wei J, et al. The Dosage of the Derivative of Clostridium Ghonii (DCG) Spores Dictates Whether an IFNγ/IL-9 or a Strong IFNγ Response Is Elicited in TC-1 Tumour Bearing Mice. Biomed Res Int. 2019;2019:1395138 pubmed publisher |
| Kim J, Kim S, Park J, Hwang S, Choi J, Jung K, et al. Metformin improves salivary gland inflammation and hypofunction in murine Sjögren's syndrome. Arthritis Res Ther. 2019;21:136 pubmed publisher |
| Yamamoto A, Hester J, Macklin P, Kawai K, Uchiyama M, Biggs D, et al. Systemic silencing of PHD2 causes reversible immune regulatory dysfunction. J Clin Invest. 2019;130:3640-3656 pubmed publisher |
| Walens A, DiMarco A, Lupo R, Kroger B, Damrauer J, Alvarez J. CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors. elife. 2019;8: pubmed publisher |
| Srivastava S, Salter A, Liggitt D, Yechan Gunja S, Sarvothama M, Cooper K, et al. Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting. Cancer Cell. 2019;35:489-503.e8 pubmed publisher |
| Feng Y, Tang M, Suzuki M, Gunasekara C, Anbe Y, Hiraoka Y, et al. Essential Role of NADPH Oxidase-Dependent Production of Reactive Oxygen Species in Maintenance of Sustained B Cell Receptor Signaling and B Cell Proliferation. J Immunol. 2019;202:2546-2557 pubmed publisher |
| Mentrup T, Theodorou K, Cabrera Cabrera F, Helbig A, Happ K, Gijbels M, et al. Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis. J Exp Med. 2019;: pubmed publisher |
| Straub T, Pircher H. Enhancing immunity prevents virus-induced T-cell-mediated immunopathology in B cell-deficient mice. Eur J Immunol. 2019;49:782-789 pubmed publisher |
| Schrock D, Leddon S, Hughson A, Miller J, Lacy Hulbert A, Fowell D. Pivotal role for αV integrins in sustained Tfh support of the germinal center response for long-lived plasma cell generation. Proc Natl Acad Sci U S A. 2019;: pubmed publisher |
| Paudel S, Baral P, Ghimire L, Bergeron S, Jin L, De Corte J, et al. CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3. Blood. 2019;: pubmed publisher |
| Lee Y, Ju J, Shon W, Oh S, Min C, Kang M, et al. Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD. Immune Netw. 2018;18:e44 pubmed publisher |
| Amir M, Chaudhari S, Wang R, Campbell S, Mosure S, Chopp L, et al. REV-ERBα Regulates TH17 Cell Development and Autoimmunity. Cell Rep. 2018;25:3733-3749.e8 pubmed publisher |
| Tan H, Jegaskanda S, Juno J, Esterbauer R, Wong J, Kelly H, et al. Subdominance and poor intrinsic immunogenicity limit humoral immunity targeting influenza HA stem. J Clin Invest. 2019;129:850-862 pubmed publisher |
| Zhang W, Li Q, Li D, Li J, Aki D, Liu Y. The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation. J Exp Med. 2018;215:3180-3193 pubmed publisher |
| Kunze Schumacher H, Winter S, Imelmann E, Krueger A. miRNA miR-21 Is Largely Dispensable for Intrathymic T-Cell Development. Front Immunol. 2018;9:2497 pubmed publisher |
| Thierry G, Kuka M, De Giovanni M, Mondor I, Brouilly N, Iannacone M, et al. The conduit system exports locally secreted IgM from lymph nodes. J Exp Med. 2018;215:2972-2983 pubmed publisher |
| Scutts S, Ember S, Ren H, Ye C, Lovejoy C, Mazzon M, et al. DNA-PK Is Targeted by Multiple Vaccinia Virus Proteins to Inhibit DNA Sensing. Cell Rep. 2018;25:1953-1965.e4 pubmed publisher |
| Hsu J, Dayaram T, Tovy A, De Braekeleer E, Jeong M, Wang F, et al. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy. Cell Stem Cell. 2018;23:700-713.e6 pubmed publisher |
| Oike T, Kanagawa H, Sato Y, Kobayashi T, Nakatsukasa H, Miyamoto K, et al. IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse. Sci Rep. 2018;8:15783 pubmed publisher |
| Humblet Baron S, Barber J, Roca C, Lenaerts A, Koni P, Liston A. Murine myeloproliferative disorder as a consequence of impaired collaboration between dendritic cells and CD4 T cells. Blood. 2018;: pubmed publisher |
| Irons E, Lau J. Systemic ST6Gal-1 Is a Pro-survival Factor for Murine Transitional B Cells. Front Immunol. 2018;9:2150 pubmed publisher |
| Giambra V, Gusscott S, Gracias D, Song R, Lam S, Panelli P, et al. Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity. Cell Stem Cell. 2018;23:714-726.e7 pubmed publisher |
| Andreani V, Ramamoorthy S, Pandey A, Lupar E, Nutt S, Lämmermann T, et al. Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function. Proc Natl Acad Sci U S A. 2018;115:E9630-E9639 pubmed publisher |
| Plantamura E, Dzutsev A, Chamaillard M, Djebali S, Moudombi L, Boucinha L, et al. MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype. Proc Natl Acad Sci U S A. 2018;115:10404-10409 pubmed publisher |
| Xu R, Fang Y, Hou C, Zhai B, Jiang Z, Ma N, et al. BC094916 suppressed SP 2/0 xenograft tumor by down-regulating Creb1 and Bcl2 transcription. Cancer Cell Int. 2018;18:138 pubmed publisher |
| Sequeira I, Neves J, Carrero D, Peng Q, Palasz N, Liakath Ali K, et al. Immunomodulatory role of Keratin 76 in oral and gastric cancer. Nat Commun. 2018;9:3437 pubmed publisher |
| Ko Y, Chan Y, Liu C, Liang J, Chuang T, Hsueh Y, et al. Blimp-1-Mediated Pathway Promotes Type I IFN Production in Plasmacytoid Dendritic Cells by Targeting to Interleukin-1 Receptor-Associated Kinase M. Front Immunol. 2018;9:1828 pubmed publisher |
| Lee S, North K, Kim E, Jang E, Obeng E, Lu S, et al. Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations. Cancer Cell. 2018;34:225-241.e8 pubmed publisher |
| Cunningham C, Hoppins S, Fink P. Cutting Edge: Glycolytic Metabolism and Mitochondrial Metabolism Are Uncoupled in Antigen-Activated CD8+ Recent Thymic Emigrants. J Immunol. 2018;201:1627-1632 pubmed publisher |
| Guo H, Barberi T, Suresh R, Friedman A. Progression from the Common Lymphoid Progenitor to B/Myeloid PreproB and ProB Precursors during B Lymphopoiesis Requires C/EBPα. J Immunol. 2018;201:1692-1704 pubmed publisher |
| Xing S, Shao P, Li F, Zhao X, Seo W, Wheat J, et al. Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity. J Exp Med. 2018;215:2211-2226 pubmed publisher |
| Urata S, Kenyon E, Nayak D, Cubitt B, Kurosaki Y, Yasuda J, et al. BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection. PLoS Pathog. 2018;14:e1007172 pubmed publisher |
| Sin S, Eason A, Bigi R, Kim Y, Kang S, Tan K, et al. Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Renders B Cells Hyperresponsive to Secondary Infections. J Virol. 2018;92: pubmed publisher |
| Qian G, Jiang W, Zou B, Feng J, Cheng X, Gu J, et al. LPS inactivation by a host lipase allows lung epithelial cell sensitization for allergic asthma. J Exp Med. 2018;215:2397-2412 pubmed publisher |
| Kim H, Park M, Lee S, Park J, Lee H, Bae Y. Activation of formyl peptide receptor 2 by WKYMVm enhances emergency granulopoiesis through phospholipase C activity. BMB Rep. 2018;51:418-423 pubmed |
| Burke A, Sutherland B, Telford D, Morrow M, Sawyez C, Edwards J, et al. Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr-/- mice. J Lipid Res. 2018;59:1714-1728 pubmed publisher |
| Dickinson G, Levenson E, Walker J, Kearney J, Alugupalli K. IL-7 Enables Antibody Responses to Bacterial Polysaccharides by Promoting B Cell Receptor Diversity. J Immunol. 2018;201:1229-1240 pubmed publisher |
| Rogers M, Lamens K, Shafagati N, Johnson M, Oury T, Joyce S, et al. CD4+ Regulatory T Cells Exert Differential Functions during Early and Late Stages of the Immune Response to Respiratory Viruses. J Immunol. 2018;201:1253-1266 pubmed publisher |
| Umemoto T, Hashimoto M, Matsumura T, Nakamura Ishizu A, Suda T. Ca2+-mitochondria axis drives cell division in hematopoietic stem cells. J Exp Med. 2018;215:2097-2113 pubmed publisher |
| Wang X, Dong F, Zhang S, Yang W, Yu W, Wang Z, et al. TGF-?1 Negatively Regulates the Number and Function of Hematopoietic Stem Cells. Stem Cell Reports. 2018;11:274-287 pubmed publisher |
| Lam J, van den Bosch M, Wegrzyn J, Parker J, Ibrahim R, Slowski K, et al. miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling. Nat Commun. 2018;9:2418 pubmed publisher |
| Viau A, Bienaime F, Lukas K, Todkar A, Knoll M, Yakulov T, et al. Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney. EMBO J. 2018;37: pubmed publisher |
| Greenblatt S, Man N, Hamard P, Asai T, Karl D, Martínez C, et al. CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis. Cancer Cell. 2018;33:1111-1127.e5 pubmed publisher |
| Pape K, Maul R, Dileepan T, Paustian A, Gearhart P, Jenkins M. Naive B Cells with High-Avidity Germline-Encoded Antigen Receptors Produce Persistent IgM+ and Transient IgG+ Memory B Cells. Immunity. 2018;48:1135-1143.e4 pubmed publisher |
| Jones R, Cosway E, Willis C, White A, Jenkinson W, Fehling H, et al. Dynamic changes in intrathymic ILC populations during murine neonatal development. Eur J Immunol. 2018;48:1481-1491 pubmed publisher |
| Du X, Wen J, Wang Y, Karmaus P, Khatamian A, Tan H, et al. Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells. Nature. 2018;558:141-145 pubmed publisher |
| Wilhelmson A, Lantero Rodriguez M, Stubelius A, Fogelstrand P, Johansson I, Buechler M, et al. Testosterone is an endogenous regulator of BAFF and splenic B cell number. Nat Commun. 2018;9:2067 pubmed publisher |
| Shi X, Kitano A, Jiang Y, Luu V, Hoegenauer K, Nakada D. Clonal expansion and myeloid leukemia progression modeled by multiplex gene editing of murine hematopoietic progenitor cells. Exp Hematol. 2018;64:33-44.e5 pubmed publisher |
| Rothberg J, Maganti H, Jrade H, Porter C, Palidwor G, Cafariello C, et al. Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis. Cell Discov. 2018;4:21 pubmed publisher |
| Anders P, Montgomery N, Montgomery S, Bhatt A, Dittmer D, Damania B. Human herpesvirus-encoded kinase induces B cell lymphomas in vivo. J Clin Invest. 2018;128:2519-2534 pubmed publisher |
| Qian P, De Kumar B, He X, Nolte C, Gogol M, Ahn Y, et al. Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis. Cell Stem Cell. 2018;22:740-754.e7 pubmed publisher |
| Baba O, Horie T, Nakao T, Hakuno D, Nakashima Y, Nishi H, et al. MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways. Mol Cell Biol. 2018;38: pubmed publisher |
| Salas J, Chen B, Wong A, Cheng D, Van Arnam J, Witte O, et al. 18F-FAC PET Selectively Images Liver-Infiltrating CD4 and CD8 T Cells in a Mouse Model of Autoimmune Hepatitis. J Nucl Med. 2018;59:1616-1623 pubmed publisher |
| Greaves S, Peterson J, Torres R, Pelanda R. Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance. Front Immunol. 2018;9:707 pubmed publisher |
| Tanaka S, Pfleger C, Lai J, Roan F, Sun S, Ziegler S. KAP1 Regulates Regulatory T Cell Function and Proliferation in Both Foxp3-Dependent and -Independent Manners. Cell Rep. 2018;23:796-807 pubmed publisher |
| Youssef L, Rebbaa A, Pampou S, Weisberg S, Stockwell B, Hod E, et al. Increased erythrophagocytosis induces ferroptosis in red pulp macrophages in a mouse model of transfusion. Blood. 2018;: pubmed publisher |
| Fahl S, Daamen A, Crittenden R, Bender T. c-Myb Coordinates Survival and the Expression of Genes That Are Critical for the Pre-BCR Checkpoint. J Immunol. 2018;200:3450-3463 pubmed publisher |
| Xia P, Wang S, Ye B, Du Y, Li C, Xiong Z, et al. A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion. Immunity. 2018;48:688-701.e7 pubmed publisher |
| Zhou Y, Wang W, Zhao C, Wang Y, Wu H, Sun X, et al. Prostaglandin E2 Inhibits Group 2 Innate Lymphoid Cell Activation and Allergic Airway Inflammation Through E-Prostanoid 4-Cyclic Adenosine Monophosphate Signaling. Front Immunol. 2018;9:501 pubmed publisher |
| Dutton E, Camelo A, Sleeman M, Herbst R, Carlesso G, Belz G, et al. Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity. Wellcome Open Res. 2017;2:117 pubmed publisher |
| Mencarelli A, Khameneh H, Fric J, Vacca M, El Daker S, Janela B, et al. Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis. Nat Commun. 2018;9:1102 pubmed publisher |
| Yu J, Zanotti S, Schilling L, Schoenherr C, Economides A, Sanjay A, et al. Induction of the Hajdu-Cheney Syndrome Mutation in CD19 B Cells in Mice Alters B-Cell Allocation but Not Skeletal Homeostasis. Am J Pathol. 2018;188:1430-1446 pubmed publisher |
| Kim G, Gu M, Kim S, Ko K, Kye Y, Kim C, et al. Transcription Factor KLF10 Constrains IL-17-Committed Vγ4+ γδ T Cells. Front Immunol. 2018;9:196 pubmed publisher |
| Sadana P, Geyer R, Pezoldt J, Helmsing S, Huehn J, Hust M, et al. The invasin D protein from Yersinia pseudotuberculosis selectively binds the Fab region of host antibodies and affects colonization of the intestine. J Biol Chem. 2018;293:8672-8690 pubmed publisher |
| Fransen M, Benonisson H, van Maren W, Sow H, Breukel C, Linssen M, et al. A Restricted Role for FcγR in the Regulation of Adaptive Immunity. J Immunol. 2018;200:2615-2626 pubmed publisher |
| Rayasam A, Hsu M, Kijak J, Kissel L, Hernandez G, Sandor M, et al. Immune responses in stroke: how the immune system contributes to damage and healing after stroke and how this knowledge could be translated to better cures?. Immunology. 2018;154:363-376 pubmed publisher |
| Nyhoff L, Clark E, Barron B, Bonami R, Khan W, Kendall P. Bruton's Tyrosine Kinase Is Not Essential for B Cell Survival beyond Early Developmental Stages. J Immunol. 2018;200:2352-2361 pubmed publisher |
| Langlais D, Cencic R, Moradin N, Kennedy J, Ayi K, Brown L, et al. Rocaglates as dual-targeting agents for experimental cerebral malaria. Proc Natl Acad Sci U S A. 2018;115:E2366-E2375 pubmed publisher |
| Zhang H, Li H, Hillmer E, Zhao Y, Chrisikos T, Hu H, et al. Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis. Proc Natl Acad Sci U S A. 2018;115:E2311-E2319 pubmed publisher |
| Beesetty P, Wieczerzak K, Gibson J, Kaitsuka T, Luu C, Matsushita M, et al. Inactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry. Sci Rep. 2018;8:3023 pubmed publisher |
| Siracusa F, McGrath M, Maschmeyer P, Bardua M, Lehmann K, Heinz G, et al. Nonfollicular reactivation of bone marrow resident memory CD4 T cells in immune clusters of the bone marrow. Proc Natl Acad Sci U S A. 2018;115:1334-1339 pubmed publisher |
| Sundararaj S, Zhang J, Krovi S, Bedel R, Tuttle K, Veerapen N, et al. Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function. Proc Natl Acad Sci U S A. 2018;115:E1204-E1213 pubmed publisher |
| Tenno M, Kojo S, Lawir D, Hess I, Shiroguchi K, Ebihara T, et al. Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors. J Exp Med. 2018;215:595-610 pubmed publisher |
| Clarke A, Riffelmacher T, Braas D, Cornall R, Simon A. B1a B cells require autophagy for metabolic homeostasis and self-renewal. J Exp Med. 2018;215:399-413 pubmed publisher |
| Niemeyer B, Oko L, Medina E, Oldenburg D, White D, Cool C, et al. Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis. J Virol. 2018;92: pubmed publisher |
| Serrano López J, Nattamai K, Pease N, Shephard M, Wellendorf A, Sertorio M, et al. Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors. Exp Hematol. 2018;59:40-50.e3 pubmed publisher |
| Duncker P, Stoolman J, Huber A, Segal B. GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction. J Immunol. 2018;200:966-973 pubmed publisher |
| Wang J, Saijo K, Skola D, Jin C, Ma Q, Merkurjev D, et al. Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock. Proc Natl Acad Sci U S A. 2018;115:E244-E252 pubmed publisher |
| Burrack A, Malhotra D, Dileepan T, Osum K, Swanson L, Fife B, et al. Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides. J Immunol. 2018;200:477-482 pubmed publisher |
| Ibitokou S, Dillon B, Sinha M, Szczesny B, Delgadillo A, Reda Abdelrahman D, et al. Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection. J Immunol. 2018;200:643-656 pubmed publisher |
| Ibrahim M, Scozzi D, Toth K, Ponti D, Kreisel D, Menna C, et al. Naive CD4+ T Cells Carrying a TLR2 Agonist Overcome TGF-β-Mediated Tumor Immune Evasion. J Immunol. 2018;200:847-856 pubmed publisher |
| Jones G, Smith V, D Orazio S. Listeria monocytogenes Replicate in Bone Marrow-Derived CD11c+ Cells but Not in Dendritic Cells Isolated from the Murine Gastrointestinal Tract. J Immunol. 2017;199:3789-3797 pubmed publisher |
| Catalan Dibene J, Vazquez M, Luu V, Nuccio S, Karimzadeh A, Kastenschmidt J, et al. Identification of IL-40, a Novel B Cell-Associated Cytokine. J Immunol. 2017;199:3326-3335 pubmed publisher |
| Camell C, Sander J, Spadaro O, Lee A, Nguyen K, Wing A, et al. Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. Nature. 2017;550:119-123 pubmed publisher |
| Mayer C, Gazumyan A, Kara E, Gitlin A, Golijanin J, Viant C, et al. The microanatomic segregation of selection by apoptosis in the germinal center. Science. 2017;358: pubmed publisher |
| Ono Y, Pérez Gutiérrez A, Nakao T, Dai H, Camirand G, Yoshida O, et al. Graft-infiltrating PD-L1hi cross-dressed dendritic cells regulate antidonor T cell responses in mouse liver transplant tolerance. Hepatology. 2018;67:1499-1515 pubmed publisher |
| Ebina Shibuya R, Matsumoto M, Kuwahara M, Jang K, Sugai M, Ito Y, et al. Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis. J Biol Chem. 2017;292:18098-18112 pubmed publisher |
| Arkatkar T, Du S, Jacobs H, Dam E, Hou B, Buckner J, et al. B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity. J Exp Med. 2017;214:3207-3217 pubmed publisher |
| Kollek M, Voigt G, Molnar C, Murad F, Bertele D, Krombholz C, et al. Transient apoptosis inhibition in donor stem cells improves hematopoietic stem cell transplantation. J Exp Med. 2017;214:2967-2983 pubmed publisher |
| Cole C, Russler Germain D, Ketkar S, Verdoni A, Smith A, Bangert C, et al. Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies. J Clin Invest. 2017;127:3657-3674 pubmed publisher |
| Noel J, Ramser B, Cancelas J, McCormack F, Gardner J. Thermal injury of the skin induces G-CSF-dependent attenuation of EPO-mediated STAT signaling and erythroid differentiation arrest in mice. Exp Hematol. 2017;56:16-30 pubmed publisher |
| Gibb D, Liu J, Santhanakrishnan M, Natarajan P, Madrid D, Patel S, et al. B cells require Type 1 interferon to produce alloantibodies to transfused KEL-expressing red blood cells in mice. Transfusion. 2017;57:2595-2608 pubmed publisher |
| Tenno M, Shiroguchi K, Muroi S, Kawakami E, Koseki K, Kryukov K, et al. Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling. J Exp Med. 2017;214:2933-2946 pubmed publisher |
| Li L, Labuda J, Imai D, Griffey S, McSorley S. CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract. J Immunol. 2017;199:2547-2554 pubmed publisher |
| McKay J, Haro M, Daly C, Yammani R, Pang B, Swords W, et al. PD-L2 Regulates B-1 Cell Antibody Production against Phosphorylcholine through an IL-5-Dependent Mechanism. J Immunol. 2017;199:2020-2029 pubmed publisher |
| Vicetti Miguel R, Quispe Calla N, Dixon D, Foster R, Gambotto A, Pavelko S, et al. IL-4-secreting eosinophils promote endometrial stromal cell proliferation and prevent Chlamydia-induced upper genital tract damage. Proc Natl Acad Sci U S A. 2017;114:E6892-E6901 pubmed publisher |
| Weis V, Königsberger S, Amler S, Wienands J, Kiefer F. Unperturbed Immune Function despite Mutation of C-Terminal Tyrosines in Syk Previously Implicated in Signaling and Activity Regulation. Mol Cell Biol. 2017;37: pubmed publisher |
| Dang J, Bian X, Ma X, Li J, Long F, Shan S, et al. ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6?-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway. J Immunol. 2017;199:1647-1659 pubmed publisher |
| Stengel K, Barnett K, Wang J, Liu Q, Hodges E, Hiebert S, et al. Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development. Proc Natl Acad Sci U S A. 2017;114:8608-8613 pubmed publisher |
| Darrah E, Kulinski J, Mboko W, Xin G, Malherbe L, Gauld S, et al. B Cell-Specific Expression of Ataxia-Telangiectasia Mutated Protein Kinase Promotes Chronic Gammaherpesvirus Infection. J Virol. 2017;91: pubmed publisher |
| Ferris S, Zakharov P, Wan X, Calderon B, Artyomov M, Unanue E, et al. The islet-resident macrophage is in an inflammatory state and senses microbial products in blood. J Exp Med. 2017;214:2369-2385 pubmed publisher |
| Bergmann H, Roth S, Pechloff K, Kiss E, Kuhn S, Heikenwalder M, et al. Card9-dependent IL-1? regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer. Eur J Immunol. 2017;47:1342-1353 pubmed publisher |
| Miao T, Symonds A, Singh R, Symonds J, Ogbe A, Omodho B, et al. Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation. J Exp Med. 2017;214:1787-1808 pubmed publisher |
| Thanabalasuriar A, Surewaard B, Willson M, Neupane A, Stover C, Warrener P, et al. Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature. J Clin Invest. 2017;127:2249-2261 pubmed publisher |
| Xu C, Lee T, Sakurai N, Krchma K, Liu F, Li D, et al. ETV2/ER71 regulates hematopoietic regeneration by promoting hematopoietic stem cell proliferation. J Exp Med. 2017;214:1643-1653 pubmed publisher |
| Deniset J, Surewaard B, Lee W, Kubes P. Splenic Ly6Ghigh mature and Ly6Gint immature neutrophils contribute to eradication of S. pneumoniae. J Exp Med. 2017;214:1333-1350 pubmed publisher |
| Ma S, Wan X, Deng Z, Shi L, Hao C, Zhou Z, et al. Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs. J Exp Med. 2017;214:1471-1491 pubmed publisher |
| Lee H, Tian L, Bouladoux N, Davis J, Quinones M, Belkaid Y, et al. Dendritic cells expressing immunoreceptor CD300f are critical for controlling chronic gut inflammation. J Clin Invest. 2017;127:1905-1917 pubmed publisher |
| Lehmann C, Baranska A, Heidkamp G, Heger L, Neubert K, Lühr J, et al. DC subset-specific induction of T cell responses upon antigen uptake via Fc? receptors in vivo. J Exp Med. 2017;214:1509-1528 pubmed publisher |
| Lagumersindez Denis N, Wrzos C, Mack M, Winkler A, van der Meer F, Reinert M, et al. Differential contribution of immune effector mechanisms to cortical demyelination in multiple sclerosis. Acta Neuropathol. 2017;134:15-34 pubmed publisher |
| Bruce D, Stefanski H, Vincent B, Dant T, Reisdorf S, Bommiasamy H, et al. Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease. J Clin Invest. 2017;127:1813-1825 pubmed publisher |
| Tian L, Goldstein A, Wang H, Ching Lo H, Sun Kim I, Welte T, et al. Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming. Nature. 2017;544:250-254 pubmed publisher |
| Schweighoffer E, Nys J, Vanes L, Smithers N, Tybulewicz V. TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK. J Exp Med. 2017;214:1269-1280 pubmed publisher |
| Briseño C, Gargaro M, Durai V, Davidson J, Theisen D, Anderson D, et al. Deficiency of transcription factor RelB perturbs myeloid and DC development by hematopoietic-extrinsic mechanisms. Proc Natl Acad Sci U S A. 2017;114:3957-3962 pubmed publisher |
| Nouri Shirazi M, Bible B, Zeng M, Tamjidi S, Bossart G. Phenotyping and comparing the immune cell populations of free-ranging Atlantic bottlenose dolphins (Tursiops truncatus) and dolphins under human care. BMC Vet Res. 2017;13:78 pubmed publisher |
| Lefrançais E, Ortiz Muñoz G, Caudrillier A, Mallavia B, Liu F, Sayah D, et al. The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors. Nature. 2017;544:105-109 pubmed publisher |
| Marriott C, Dutton E, Tomura M, Withers D. Retention of Ag-specific memory CD4+ T cells in the draining lymph node indicates lymphoid tissue resident memory populations. Eur J Immunol. 2017;47:860-871 pubmed publisher |
| Ansa Addo E, Zhang Y, Yang Y, Hussey G, Howley B, Salem M, et al. Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-β signaling. J Clin Invest. 2017;127:1321-1337 pubmed publisher |
| Girelli Zubani G, Zivojnovic M, De Smet A, Albagli Curiel O, Huetz F, Weill J, et al. Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs. J Exp Med. 2017;214:1169-1180 pubmed publisher |
| Ho C, Chhabra A, Starkl P, Schnorr P, Wilmes S, Moraga I, et al. Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling. Cell. 2017;168:1041-1052.e18 pubmed publisher |
| Boyoglu Barnum S, Todd S, Meng J, Barnum T, Chirkova T, Haynes L, et al. Mutating the CX3C Motif in the G Protein Should Make a Live Respiratory Syncytial Virus Vaccine Safer and More Effective. J Virol. 2017;91: pubmed publisher |
| Wang H, Qian L, Zhao Y, Mengarelli J, Adrianto I, Montgomery C, et al. Downregulation of E Protein Activity Augments an ILC2 Differentiation Program in the Thymus. J Immunol. 2017;198:3149-3156 pubmed publisher |
| Zhu H, Kwak H, Liu P, Bajrami B, Xu Y, Park S, et al. Reactive Oxygen Species-Producing Myeloid Cells Act as a Bone Marrow Niche for Sterile Inflammation-Induced Reactive Granulopoiesis. J Immunol. 2017;198:2854-2864 pubmed publisher |
| Jones G, D Orazio S. Monocytes Are the Predominant Cell Type Associated with Listeria monocytogenes in the Gut, but They Do Not Serve as an Intracellular Growth Niche. J Immunol. 2017;198:2796-2804 pubmed publisher |
| Lafuse W, Gearinger R, Fisher S, Nealer C, Mackos A, Bailey M. Exposure to a Social Stressor Induces Translocation of Commensal Lactobacilli to the Spleen and Priming of the Innate Immune System. J Immunol. 2017;198:2383-2393 pubmed publisher |
| Bracamonte Baran W, Florentin J, Zhou Y, Jankowska Gan E, Haynes W, Zhong W, et al. Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance. Proc Natl Acad Sci U S A. 2017;114:1099-1104 pubmed publisher |
| Russell Knode L, Naradikian M, Myles A, Scholz J, Hao Y, Liu D, et al. Age-Associated B Cells Express a Diverse Repertoire of VH and Vκ Genes with Somatic Hypermutation. J Immunol. 2017;198:1921-1927 pubmed publisher |
| Maul R, Chon H, Sakhuja K, Cerritelli S, Gugliotti L, Gearhart P, et al. R-Loop Depletion by Over-expressed RNase H1 in Mouse B Cells Increases Activation-Induced Deaminase Access to the Transcribed Strand without Altering Frequency of Isotype Switching. J Mol Biol. 2017;429:3255-3263 pubmed publisher |
| Khairallah M, Astroski J, Custer S, Androphy E, Franklin C, Lorson C. SMN deficiency negatively impacts red pulp macrophages and spleen development in mouse models of spinal muscular atrophy. Hum Mol Genet. 2017;26:932-941 pubmed publisher |
| Holt M, Punkosdy G, Glass D, Shevach E. TCR Signaling and CD28/CTLA-4 Signaling Cooperatively Modulate T Regulatory Cell Homeostasis. J Immunol. 2017;198:1503-1511 pubmed publisher |
| Opata M, Stephens R. Chronic Plasmodium chabaudi Infection Generates CD4 Memory T Cells with Increased T Cell Receptor Sensitivity but Poor Secondary Expansion and Increased Apoptosis. Infect Immun. 2017;85: pubmed publisher |
| Xu X, Han L, Zhao G, Xue S, Gao Y, Xiao J, et al. LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis. J Exp Med. 2017;214:209-226 pubmed publisher |
| Vaidyanathan B, Chaudhry A, Yewdell W, Angeletti D, Yen W, Wheatley A, et al. The aryl hydrocarbon receptor controls cell-fate decisions in B cells. J Exp Med. 2017;214:197-208 pubmed publisher |
| Ding Q, von Schaewen M, Hrebikova G, Heller B, Sandmann L, Plaas M, et al. Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo. J Virol. 2017;91: pubmed publisher |
| Connor L, Tang S, Cognard E, Ochiai S, Hilligan K, Old S, et al. Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles. J Exp Med. 2017;214:125-142 pubmed publisher |
| Müller A, Florek M, Kohrt H, Küpper N, Filatenkov A, Linderman J, et al. Blood Stem Cell Activity Is Arrested by Th1-Mediated Injury Preventing Engraftment following Nonmyeloablative Conditioning. J Immunol. 2016;197:4151-4162 pubmed |
| Kandalla P, Sarrazin S, Molawi K, Berruyer C, Redelberger D, Favel A, et al. M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation. J Exp Med. 2016;213:2269-2279 pubmed |
| Zamora Pineda J, Kumar A, Suh J, Zhang M, Saba J. Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress. J Exp Med. 2016;213:2773-2791 pubmed |
| Dong L, Yu W, Zheng H, Loh M, Bunting S, Pauly M, et al. Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment. Nature. 2016;539:304-308 pubmed publisher |
| Sochalska M, Schuler F, Weiss J, Prchal Murphy M, Sexl V, Villunger A. MYC selects against reduced BCL2A1/A1 protein expression during B cell lymphomagenesis. Oncogene. 2017;36:2066-2073 pubmed publisher |
| Yoon J, Leyva Castillo J, Wang G, Galand C, Oyoshi M, Kumar L, et al. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016;213:2147-66 pubmed publisher |
| Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed publisher |
| Cho S, Raybuck A, Stengel K, Wei M, Beck T, Volanakis E, et al. Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system. Nature. 2016;537:234-238 pubmed publisher |
| Maul R, MacCarthy T, Frank E, Donigan K, McLenigan M, Yang W, et al. DNA polymerase ? functions in the generation of tandem mutations during somatic hypermutation of antibody genes. J Exp Med. 2016;213:1675-83 pubmed publisher |
| Ibiza S, García Cassani B, Ribeiro H, Carvalho T, Almeida L, Marques R, et al. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 2016;535:440-443 pubmed publisher |
| Schmitt H, Sell S, Koch J, Seefried M, Sonnewald S, Daniel C, et al. Siglec-H protects from virus-triggered severe systemic autoimmunity. J Exp Med. 2016;213:1627-44 pubmed publisher |
| Huang B, Gomez Rodriguez J, Preite S, Garrett L, Harper U, Schwartzberg P. CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development. PLoS ONE. 2016;11:e0156072 pubmed publisher |
| Katagiri S, Park K, Maeda Y, Rao T, Khamaisi M, Li Q, et al. Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance. Diabetes. 2016;65:2760-71 pubmed publisher |
| Xu J, Zhou L, Ji L, Chen F, Fortmann K, Zhang K, et al. The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis. Nat Commun. 2016;7:10761 pubmed publisher |
| Duhan V, Khairnar V, Friedrich S, Zhou F, Gassa A, Honke N, et al. Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8(+) T-cell priming and viral control. Sci Rep. 2016;6:19191 pubmed publisher |
| Olsen D, Goar W, Nichols B, Bailey K, Christensen S, Merriam K, et al. Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model. Biomed Res Int. 2015;2015:975789 pubmed publisher |
| Louveau A, Smirnov I, Keyes T, Eccles J, Rouhani S, Peske J, et al. Structural and functional features of central nervous system lymphatic vessels. Nature. 2015;523:337-41 pubmed publisher |
| Hu J, Oda S, Shotts K, Donovan E, Strauch P, Pujanauski L, et al. Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response. J Immunol. 2014;193:85-95 pubmed publisher |
| Mahmud S, Manlove L, Schmitz H, Xing Y, Wang Y, Owen D, et al. Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells. Nat Immunol. 2014;15:473-81 pubmed publisher |
| Aslam M, Kishi Y, Tsubata T. Excess CD40L does not rescue anti-DNA B cells from clonal anergy. F1000Res. 2013;2:218 pubmed publisher |
| Keating R, Hertz T, Wehenkel M, Harris T, Edwards B, McClaren J, et al. The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus. Nat Immunol. 2013;14:1266-76 pubmed publisher |
| Wang S, Tasch J, Kheradmand T, Ulaszek J, Ely S, Zhang X, et al. Transient B-cell depletion combined with apoptotic donor splenocytes induces xeno-specific T- and B-cell tolerance to islet xenografts. Diabetes. 2013;62:3143-50 pubmed publisher |
| Torrado E, Fountain J, Robinson R, Martino C, Pearl J, Rangel Moreno J, et al. Differential and site specific impact of B cells in the protective immune response to Mycobacterium tuberculosis in the mouse. PLoS ONE. 2013;8:e61681 pubmed publisher |
| Balamurugan K, Sharan S, Klarmann K, Zhang Y, Coppola V, Summers G, et al. FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4. Nat Commun. 2013;4:1662 pubmed publisher |
| Arcipowski K, Bishop G. TRAF binding is required for a distinct subset of in vivo B cell functions of the oncoprotein LMP1. J Immunol. 2012;189:5165-70 pubmed publisher |
| Powers S, Mandal M, Matsuda S, Miletic A, Cato M, Tanaka A, et al. Subnuclear cyclin D3 compartments and the coordinated regulation of proliferation and immunoglobulin variable gene repression. J Exp Med. 2012;209:2199-213 pubmed publisher |
| Castillo E, Dekonenko A, Arko Mensah J, Mandell M, Dupont N, Jiang S, et al. Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation. Proc Natl Acad Sci U S A. 2012;109:E3168-76 pubmed publisher |
| Ramon S, Bancos S, Thatcher T, Murant T, Moshkani S, Sahler J, et al. Peroxisome proliferator-activated receptor ? B cell-specific-deficient mice have an impaired antibody response. J Immunol. 2012;189:4740-7 pubmed publisher |
| Van V, Raymond M, Baba N, Rubio M, Wakahara K, Susin S, et al. CD47(high) expression on CD4 effectors identifies functional long-lived memory T cell progenitors. J Immunol. 2012;188:4249-55 pubmed publisher |
| Wensveen F, Unger P, Kragten N, Derks I, ten Brinke A, Arens R, et al. CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load. J Immunol. 2012;188:4256-67 pubmed publisher |
| Savage A, Constantinides M, Han J, Picard D, Martin E, Li B, et al. The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity. 2008;29:391-403 pubmed publisher |
| Forbes E, Groschwitz K, Abonia J, Brandt E, Cohen E, Blanchard C, et al. IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity. J Exp Med. 2008;205:897-913 pubmed publisher |
| Labi V, Erlacher M, Kiessling S, Manzl C, Frenzel A, O Reilly L, et al. Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development. J Exp Med. 2008;205:641-55 pubmed publisher |
| Meyer Bahlburg A, Andrews S, Yu K, Porcelli S, Rawlings D. Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation. J Exp Med. 2008;205:155-68 pubmed publisher |
| Guikema J, Linehan E, Tsuchimoto D, Nakabeppu Y, Strauss P, Stavnezer J, et al. APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination. J Exp Med. 2007;204:3017-26 pubmed |
| Albu D, Feng D, Bhattacharya D, Jenkins N, Copeland N, Liu P, et al. BCL11B is required for positive selection and survival of double-positive thymocytes. J Exp Med. 2007;204:3003-15 pubmed |
| Anderson S, Tomayko M, Ahuja A, Haberman A, Shlomchik M. New markers for murine memory B cells that define mutated and unmutated subsets. J Exp Med. 2007;204:2103-14 pubmed |
| Sun C, Hall J, Blank R, Bouladoux N, Oukka M, Mora J, et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med. 2007;204:1775-85 pubmed |
| Besseyrias V, Fiorini E, Strobl L, Zimber Strobl U, Dumortier A, Koch U, et al. Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. J Exp Med. 2007;204:331-43 pubmed |
| Lahl K, Loddenkemper C, Drouin C, Freyer J, Arnason J, Eberl G, et al. Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease. J Exp Med. 2007;204:57-63 pubmed |
| Savitsky D, Calame K. B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion. J Exp Med. 2006;203:2305-14 pubmed |
| Bajenoff M, Breart B, Huang A, Qi H, Cazareth J, Braud V, et al. Natural killer cell behavior in lymph nodes revealed by static and real-time imaging. J Exp Med. 2006;203:619-31 pubmed |
| Kallies A, Hasbold J, Tarlinton D, Dietrich W, Corcoran L, Hodgkin P, et al. Plasma cell ontogeny defined by quantitative changes in blimp-1 expression. J Exp Med. 2004;200:967-77 pubmed |
| Shiratori I, Ogasawara K, Saito T, Lanier L, Arase H. Activation of natural killer cells and dendritic cells upon recognition of a novel CD99-like ligand by paired immunoglobulin-like type 2 receptor. J Exp Med. 2004;199:525-33 pubmed |
| Cobas M, Wilson A, Ernst B, Mancini S, MacDonald H, Kemler R, et al. Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. J Exp Med. 2004;199:221-9 pubmed |
| Singh N, Schwartz R. The strength of persistent antigenic stimulation modulates adaptive tolerance in peripheral CD4+ T cells. J Exp Med. 2003;198:1107-17 pubmed |
| Bajenoff M, Granjeaud S, Guerder S. The strategy of T cell antigen-presenting cell encounter in antigen-draining lymph nodes revealed by imaging of initial T cell activation. J Exp Med. 2003;198:715-24 pubmed |
| Nolte M, Belien J, Schadee Eestermans I, Jansen W, Unger W, Van Rooijen N, et al. A conduit system distributes chemokines and small blood-borne molecules through the splenic white pulp. J Exp Med. 2003;198:505-12 pubmed |
| Okazaki I, Hiai H, Kakazu N, Yamada S, Muramatsu M, Kinoshita K, et al. Constitutive expression of AID leads to tumorigenesis. J Exp Med. 2003;197:1173-81 pubmed |
| Miller J, Izon D, DeMuth W, Gerstein R, Bhandoola A, Allman D. The earliest step in B lineage differentiation from common lymphoid progenitors is critically dependent upon interleukin 7. J Exp Med. 2002;196:705-11 pubmed |
| Street S, Trapani J, MacGregor D, Smyth M. Suppression of lymphoma and epithelial malignancies effected by interferon gamma. J Exp Med. 2002;196:129-34 pubmed |
| Lambolez F, Azogui O, Joret A, Garcia C, von Boehmer H, Di Santo J, et al. Characterization of T cell differentiation in the murine gut. J Exp Med. 2002;195:437-49 pubmed |
| Takaki S, Morita H, Tezuka Y, Takatsu K. Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk. J Exp Med. 2002;195:151-60 pubmed |
| Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, Rivera M, et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med. 2001;194:769-79 pubmed |
| Ellmeier W, Jung S, Sunshine M, Hatam F, Xu Y, Baltimore D, et al. Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk. J Exp Med. 2000;192:1611-24 pubmed |
| Smyth M, Thia K, Street S, MacGregor D, Godfrey D, Trapani J. Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma. J Exp Med. 2000;192:755-60 pubmed |
