CD80 Monoclonal Antibody (RMMP-1) | Invitrogen MA1-70090 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD80 Monoclonal Antibody (RMMP-1)

catalog :

MA1-70090

quantity :

200 ug

price :

US 452.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

RMMP-1

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 1d	Khan A, Fu H, Tan L, Harper J, Beutelspacher S, Larkin D, et al. Dendritic cell modification as a route to inhibiting corneal graft rejection by the indirect pathway of allorecognition. Eur J Immunol. 2013;43:734-46 pubmed publisher
flow cytometry; mouse; fig 1	Jenkins S, Mountford A. Dendritic cells activated with products released by schistosome larvae drive Th2-type immune responses, which can be inhibited by manipulation of CD40 costimulation. Infect Immun. 2005;73:395-402 pubmed
flow cytometry; mouse; 1:50; fig 1	Freyschmidt E, Alonso A, Hartmann G, Gissmann L. Activation of dendritic cells and induction of T cell responses by HPV 16 L1/E7 chimeric virus-like particles are enhanced by CpG ODN or sorbitol. Antivir Ther. 2004;9:479-89 pubmed
flow cytometry; mouse	Morin J, Faideau B, Gagnerault M, Lepault F, Boitard C, Boudaly S. Passive transfer of flt-3L-derived dendritic cells delays diabetes development in NOD mice and associates with early production of interleukin (IL)-4 and IL-10 in the spleen of recipient mice. Clin Exp Immunol. 2003;134:388-95 pubmed
flow cytometry; mouse; fig 2	Cabatingan M, Schmidt M, Sen R, Woodland R. Naive B lymphocytes undergo homeostatic proliferation in response to B cell deficit. J Immunol. 2002;169:6795-805 pubmed
flow cytometry; mouse; 0.5 ug/ml	Denda Nagai K, Kubota N, Tsuiji M, Kamata M, Irimura T. Macrophage C-type lectin on bone marrow-derived immature dendritic cells is involved in the internalization of glycosylated antigens. Glycobiology. 2002;12:443-50 pubmed
flow cytometry; mouse; fig 5	Magner W, Kazim A, Stewart C, Romano M, Catalano G, Grande C, et al. Activation of MHC class I, II, and CD40 gene expression by histone deacetylase inhibitors. J Immunol. 2000;165:7017-24 pubmed
	Swope D, Li J, Muller E, Radice G. Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability. Genesis. 2012;50:717-27 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD80 Monoclonal Antibody (RMMP-1)

Catalog # :

MA1-70090

Quantity :

200 ug

Price :

US 452.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 ug/1 million cells

Species :

Mouse

Clone :

RMMP-1

Isotype :

IgG2a

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Immunogen :

Mouse B7-1 protein.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/1 million cells

Aliases :

Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1

more info or order :

Invitrogen product webpage