| Published Application/Species/Sample/Dilution | Reference |
|---|
- flow cytometry; mouse; loading ...; fig s1f
| Gopal A, Ibrahim R, Fuller M, Umlandt P, Parker J, Tran J, et al. TIRAP drives myelosuppression through an Ifnγ-Hmgb1 axis that disrupts the endothelial niche in mice. J Exp Med. 2022;219: pubmed publisher |
- flow cytometry; mouse; 1:100; loading ...
| Tsutsui K, Machida H, Nakagawa A, Ahn K, Morita R, Sekiguchi K, et al. Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions. Nat Commun. 2021;12:2577 pubmed publisher |
- flow cytometry; mouse; 1:200; loading ...
| Ricci B, Tycksen E, Celik H, Belle J, Fontana F, Civitelli R, et al. Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics. elife. 2020;9: pubmed publisher |
- flow cytometry; mouse; loading ...
| Choi S, Bae H, Jeong S, Park I, Cho H, Hong S, et al. YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells. Nat Commun. 2020;11:519 pubmed publisher |
- flow cytometry; mouse; 1:100; loading ...; fig e1a
| Vagnozzi R, Maillet M, Sargent M, Khalil H, Johansen A, Schwanekamp J, et al. An acute immune response underlies the benefit of cardiac stem cell therapy. Nature. 2020;577:405-409 pubmed publisher |
- flow cytometry; mouse; 1:500; loading ...; fig e2j, 4g
| Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s3a
| Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s1e
| Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, et al. An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion. Cell Stem Cell. 2018;22:879-892.e6 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 2a
| Rothberg J, Maganti H, Jrade H, Porter C, Palidwor G, Cafariello C, et al. Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis. Cell Discov. 2018;4:21 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 3e
| Chennupati V, Veiga D, Maslowski K, Andina N, Tardivel A, Yu E, et al. Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation. J Clin Invest. 2018;128:1597-1614 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s4c
| Vo L, Kinney M, Liu X, Zhang Y, Barragan J, Sousa P, et al. Regulation of embryonic haematopoietic multipotency by EZH1. Nature. 2018;553:506-510 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 2d
| Guarnerio J, Mendez L, Asada N, Menon A, Fung J, Berry K, et al. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nat Commun. 2018;9:66 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 4a
| Cole C, Russler Germain D, Ketkar S, Verdoni A, Smith A, Bangert C, et al. Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies. J Clin Invest. 2017;127:3657-3674 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s1.4b
| Audzevich T, Bashford Rogers R, Mabbott N, Frampton D, Freeman T, Potocnik A, et al. Pre/pro-B cells generate macrophage populations during homeostasis and inflammation. Proc Natl Acad Sci U S A. 2017;114:E3954-E3963 pubmed publisher |
| Bruce D, Stefanski H, Vincent B, Dant T, Reisdorf S, Bommiasamy H, et al. Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease. J Clin Invest. 2017;127:1813-1825 pubmed publisher |
- flow cytometry; mouse; 1:100; loading ...; fig 1a
| Katerndahl C, Heltemes Harris L, Willette M, Henzler C, Frietze S, Yang R, et al. Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival. Nat Immunol. 2017;18:694-704 pubmed publisher |
- flow cytometry; mouse; tbl 1
| Gatto S, Puri P, Malecova B. Single Cell Gene Expression Profiling of Skeletal Muscle-Derived Cells. Methods Mol Biol. 2017;1556:191-219 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 4a
| Stanley R, Piszczatowski R, Bartholdy B, Mitchell K, McKimpson W, Narayanagari S, et al. A myeloid tumor suppressor role for NOL3. J Exp Med. 2017;214:753-771 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s2
| Cañete A, Carmona R, Ariza L, Sanchez M, Rojas A, Muñoz Chápuli R. A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice. Haematologica. 2017;102:647-655 pubmed publisher |
- flow cytometry; mouse; loading ...
| Costa D, Principi E, Lazzarini E, Descalzi F, Cancedda R, Castagnola P, et al. LCN2 overexpression in bone enhances the hematopoietic compartment via modulation of the bone marrow microenvironment. J Cell Physiol. 2017;232:3077-3087 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 1b
| Kretzer N, Theisen D, Tussiwand R, Briseño C, Grajales Reyes G, Wu X, et al. RAB43 facilitates cross-presentation of cell-associated antigens by CD8?+ dendritic cells. J Exp Med. 2016;213:2871-2883 pubmed |
- flow cytometry; mouse; loading ...
| Le Q, Yao W, Chen Y, Yan B, Liu C, Yuan M, et al. GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal. Cell Death Dis. 2016;7:e2478 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s2d
| Dong L, Yu W, Zheng H, Loh M, Bunting S, Pauly M, et al. Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment. Nature. 2016;539:304-308 pubmed publisher |
- flow cytometry; mouse; loading ...
| Ramirez Carrozzi V, Sambandam A, Zhou M, Yan D, Kang J, Wu X, et al. Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone. J Allergy Clin Immunol. 2017;139:705-708.e6 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 1d
| Uckelmann H, Blaszkiewicz S, Nicolae C, Haas S, Schnell A, Wurzer S, et al. Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4. J Exp Med. 2016;213:1961-71 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 1a
| Chen S, Miyazaki M, Chandra V, Fisch K, Chang A, Murre C. Id3 Orchestrates Germinal Center B Cell Development. Mol Cell Biol. 2016;36:2543-52 pubmed publisher |
- flow cytometry; mouse; fig 6a
| Li L, Benoun J, Weiskopf K, Garcia K, McSorley S. Salmonella Infection Enhances Erythropoietin Production by the Kidney and Liver, Which Correlates with Elevated Bacterial Burdens. Infect Immun. 2016;84:2833-41 pubmed publisher |
- flow cytometry; mouse; loading ...; fig ex1b
| Hoppe P, Schwarzfischer M, Loeffler D, Kokkaliaris K, Hilsenbeck O, Moritz N, et al. Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios. Nature. 2016;535:299-302 pubmed publisher |
- flow cytometry; mouse; loading ...; fig s1h
| Ibiza S, García Cassani B, Ribeiro H, Carvalho T, Almeida L, Marques R, et al. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 2016;535:440-443 pubmed publisher |
- flow cytometry; mouse; loading ...
| Keil M, Sonner J, Lanz T, Oezen I, Bunse T, Bittner S, et al. General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation. J Neuroimmunol. 2016;297:117-26 pubmed publisher |
- flow cytometry; mouse; loading ...
| Jabara H, Boyden S, Chou J, Ramesh N, Massaad M, Benson H, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016;48:74-8 pubmed publisher |
- flow cytometry; mouse; loading ...
| Cole C, Verdoni A, Ketkar S, Leight E, Russler Germain D, Lamprecht T, et al. PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia. J Clin Invest. 2016;126:85-98 pubmed publisher |
- flow cytometry; mouse; 1:900
| Harland K, Day E, Apte S, Russ B, Doherty P, Turner S, et al. Epigenetic plasticity of Cd8a locus during CD8(+) T-cell development and effector differentiation and reprogramming. Nat Commun. 2014;5:3547 pubmed publisher |
| Kanwar N, Fayyazi A, Backofen B, Nitsche M, Dressel R, von Mollard G. Thymic alterations in mice deficient for the SNARE protein VAMP8/endobrevin. Cell Tissue Res. 2008;334:227-42 pubmed publisher |
| Liang Z, Goradia A, Walkley C, Heraud Farlow J. Generation of a new Adar1p150 -/- mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis. RNA. 2023;29:1325-1338 pubmed publisher |
| Pizzato H, Wang Y, Wolfgang M, Finck B, Patti G, Bhattacharya D. Mitochondrial pyruvate metabolism and glutaminolysis toggle steady-state and emergency myelopoiesis. J Exp Med. 2023;220: pubmed publisher |
| Herrejon Chavez F, Luo H, Cifani P, Pine A, Chu K, Joshi S, et al. RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nat Commun. 2023;14:2290 pubmed publisher |
| Talwar D, Miller C, Grossmann J, Szyrwiel L, Schwecke T, Demichev V, et al. The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells. Nat Metab. 2023;5:660-676 pubmed publisher |
| Leclerc K, Remark L, Ramsukh M, Josephson A, Palma L, Parente P, et al. Hox genes are crucial regulators of periosteal stem cell identity. Development. 2023;150: pubmed publisher |
| Han X, Mei Y, Mishra R, Bi H, Jain A, Schiltz G, et al. Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models. J Clin Invest. 2023;133: pubmed publisher |
| Yoshinaga M, Han K, Morgens D, Horii T, Kobayashi R, Tsuruyama T, et al. The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity. Nat Commun. 2022;13:6435 pubmed publisher |
| Wu R, Ohara R, Jo S, Liu T, Ferris S, Ou F, et al. Mechanisms of CD40-dependent cDC1 licensing beyond costimulation. Nat Immunol. 2022;23:1536-1550 pubmed publisher |
| Hutter K, R xfc licke T, Szabó T, Andersen L, Villunger A, Herzog S. The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression. Front Immunol. 2022;13:967914 pubmed publisher |
| Kim K, Mura Meszaros A, Tollot M, Krishnan M, Gr xfc ndl M, Neubert L, et al. Taz protects hematopoietic stem cells from an aging-dependent decrease in PU.1 activity. Nat Commun. 2022;13:5187 pubmed publisher |
| Gros M, Segura E, Rookhuizen D, Baudon B, Heurtebise Chr xe9 tien S, Burgdorf N, et al. Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation. Cell Rep. 2022;40:111205 pubmed publisher |
| Cao L, Morgun E, Genardi S, Visvabharathy L, Cui Y, Huang H, et al. METTL14-dependent m6A modification controls iNKT cell development and function. Cell Rep. 2022;40:111156 pubmed publisher |
| Ray S, Chee L, Zhou Y, Schaefer M, Naldrett M, Alvarez S, et al. Functional requirements for a Samd14-capping protein complex in stress erythropoiesis. elife. 2022;11: pubmed publisher |
| Yang H, Ting X, Geng Y, Xie Y, Nierenberg J, Huo Y, et al. The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression. Sci Adv. 2022;8:eabn3509 pubmed publisher |
| Shue Y, Drainas A, Li N, Pearsall S, Morgan D, Sinnott Armstrong N, et al. A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs. Nat Commun. 2022;13:2690 pubmed publisher |
| Wu X, He X, Ipsaro J, Huang Y, Preall J, Ng D, et al. OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage. Nature. 2022;607:169-175 pubmed publisher |
| Aurora A, Khivansara V, Leach A, Gill J, Martin Sandoval M, Yang C, et al. Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher |
| Beauchamp E, Leventhal M, Bernard E, Hoppe E, Todisco G, Creignou M, et al. ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Blood Cancer Discov. 2021;2:500-517 pubmed publisher |
| Gokey J, Snowball J, Sridharan A, Sudha P, Kitzmiller J, Xu Y, et al. YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1. iScience. 2021;24:102967 pubmed publisher |
| Wei X, Meel M, Breur M, Bugiani M, Hulleman E, Phoenix T. Defining tumor-associated vascular heterogeneity in pediatric high-grade and diffuse midline gliomas. Acta Neuropathol Commun. 2021;9:142 pubmed publisher |
| Bi X, Du C, Wang X, Wang X, Han W, Wang Y, et al. Mitochondrial Damage-Induced Innate Immune Activation in Vascular Smooth Muscle Cells Promotes Chronic Kidney Disease-Associated Plaque Vulnerability. Adv Sci (Weinh). 2021;8:2002738 pubmed publisher |
| Smith L, Verovskaya E, Bieri G, Horowitz A, von Ungern Sternberg S, Lin K, et al. The aged hematopoietic system promotes hippocampal-dependent cognitive decline. Aging Cell. 2020;19:e13192 pubmed publisher |
| Cendrowski J, Kaczmarek M, Mazur M, Kuzmicz Kowalska K, Jastrzębski K, Brewińska Olchowik M, et al. Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells. elife. 2020;9: pubmed publisher |
| Huang F, Sun J, Chen W, He X, Zhu Y, Dong H, et al. HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML. Aging (Albany NY). 2020;12:16759-16774 pubmed publisher |
| Oguri Y, Shinoda K, Kim H, Alba D, Bolus W, Wang Q, et al. CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling. Cell. 2020;: pubmed publisher |
| Nasrallah R, Imianowski C, Bossini Castillo L, Grant F, Dogan M, Placek L, et al. A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells. Nature. 2020;583:447-452 pubmed publisher |
| Tummers B, Mari L, Guy C, Heckmann B, Rodriguez D, Rühl S, et al. Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis. Immunity. 2020;52:994-1006.e8 pubmed publisher |
| Kim J, Yang Y, Park K, Ge X, Xu R, Li N, et al. A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nat Commun. 2020;11:2289 pubmed publisher |
| Houri K, Mori T, Onodera Y, Tsujimoto T, Takehara T, Nakao S, et al. miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells. Sci Rep. 2020;10:3735 pubmed publisher |
| Matsushima S, Aoshima Y, Akamatsu T, Enomoto Y, Meguro S, Kosugi I, et al. CD248 and integrin alpha-8 are candidate markers for differentiating lung fibroblast subtypes. BMC Pulm Med. 2020;20:21 pubmed publisher |
| Tasdogan A, Faubert B, Ramesh V, Ubellacker J, Shen B, Solmonson A, et al. Metabolic heterogeneity confers differences in melanoma metastatic potential. Nature. 2020;577:115-120 pubmed publisher |
| Huerga Encabo H, Traveset L, Argilaguet J, Angulo A, Nistal Villán E, Jaiswal R, et al. The transcription factor NFAT5 limits infection-induced type I interferon responses. J Exp Med. 2020;217: pubmed publisher |
| Hilgendorf K, Johnson C, Mezger A, Rice S, Norris A, Demeter J, et al. Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis. Cell. 2019;179:1289-1305.e21 pubmed publisher |
| Hirukawa A, Singh S, Wang J, Rennhack J, Swiatnicki M, Sanguin Gendreau V, et al. Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy. Cell Rep. 2019;29:249-257.e8 pubmed publisher |
| Chen L, Strohmeier V, He Z, Deshpande M, Catalan Dibene J, Durum S, et al. Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23. Nat Commun. 2019;10:4517 pubmed publisher |
| Nachmani D, Bothmer A, Grisendi S, Mele A, Bothmer D, Lee J, et al. Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita. Nat Genet. 2019;51:1518-1529 pubmed publisher |
| Kasitinon S, Eskiocak U, Martin M, Bezwada D, Khivansara V, Tasdogan A, et al. TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling. Cell Rep. 2019;28:2293-2305.e9 pubmed publisher |
| Guillamot M, Ouazia D, Dolgalev I, Yeung S, Kourtis N, Dai Y, et al. The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation. Nat Immunol. 2019;20:1196-1207 pubmed publisher |
| Wang N, Fan Y, Yuan C, Song J, Yao Y, Liu W, et al. Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity. BMC Cancer. 2019;19:764 pubmed publisher |
| Gross K, Zhou W, Breindel J, Ouyang J, Jin D, Sokol E, et al. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Cell Rep. 2019;28:394-407.e6 pubmed publisher |
| Wang H, Xiang D, Liu B, He A, Randle H, Zhang K, et al. Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer. Cell. 2019;178:135-151.e19 pubmed publisher |
| Nandakumar S, McFarland S, Mateyka L, Lareau C, Ulirsch J, Ludwig L, et al. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis. elife. 2019;8: pubmed publisher |
| Zhang J, Supakorndej T, Krambs J, Rao M, Abou Ezzi G, Ye R, et al. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest. 2019;129:2920-2931 pubmed publisher |
| Qian L, Bajana S, Georgescu C, Peng V, Wang H, Adrianto I, et al. Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors. J Exp Med. 2019;216:884-899 pubmed publisher |
| Łyszkiewicz M, Winter S, Witzlau K, Föhse L, Brownlie R, Puchałka J, et al. miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity. PLoS Biol. 2019;17:e2006716 pubmed publisher |
| Shimizu H, Takeishi S, Nakatsumi H, Nakayama K. Prevention of cancer dormancy by Fbxw7 ablation eradicates disseminated tumor cells. JCI Insight. 2019;4: pubmed publisher |
| Anandagoda N, Willis J, Hertweck A, Roberts L, Jackson I, Gökmen M, et al. microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance. J Clin Invest. 2019;129:1257-1271 pubmed publisher |
| Zhou Q, Yu B, Anderson C, Huang Z, Hanus J, Zhang W, et al. LncEGFL7OS regulates human angiogenesis by interacting with MAX at the EGFL7/miR-126 locus. elife. 2019;8: pubmed publisher |
| Malara A, Gruppi C, Abbonante V, Cattaneo D, De Marco L, Massa M, et al. EDA fibronectin-TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis. J Exp Med. 2019;216:587-604 pubmed publisher |
| Rowe R, Lummertz da Rocha E, Sousa P, Missios P, Morse M, Marion W, et al. The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia. J Exp Med. 2019;216:527-538 pubmed publisher |
| Paudel S, Baral P, Ghimire L, Bergeron S, Jin L, De Corte J, et al. CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3. Blood. 2019;: pubmed publisher |
| Zhang H, Brown R, Wei Y, Zhao P, Liu S, Liu X, et al. CD44 splice isoform switching determines breast cancer stem cell state. Genes Dev. 2019;33:166-179 pubmed publisher |
| Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D Elia E, et al. p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value. Cell Rep. 2019;26:624-638.e8 pubmed publisher |
| Ma J, Ng W, Zappia L, Gearing L, Olshansky M, Pham K, et al. Unique Transcriptional Architecture in Airway Epithelial Cells and Macrophages Shapes Distinct Responses following Influenza Virus Infection Ex Vivo. J Virol. 2019;93: pubmed publisher |
| Tagaya H, Ishikawa K, Hosokawa Y, Kobayashi S, Ueoka Y, Shimada M, et al. A method of producing genetically manipulated mouse mammary gland. Breast Cancer Res. 2019;21:1 pubmed publisher |
| Barros Silva J, Linn D, Steiner I, Guo G, Ali A, Pakula H, et al. Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer. Cell Rep. 2018;25:3504-3518.e6 pubmed publisher |
| Greenwald A, Licht T, Kumar S, Oladipupo S, Iyer S, Grunewald M, et al. VEGF expands erythropoiesis via hypoxia-independent induction of erythropoietin in noncanonical perivascular stromal cells. J Exp Med. 2019;216:215-230 pubmed publisher |
| Percin G, Eitler J, Kranz A, Fu J, Pollard J, Naumann R, et al. CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages. Nat Commun. 2018;9:5279 pubmed publisher |
| Menotti M, Ambrogio C, Cheong T, Pighi C, Mota I, Cassel S, et al. Wiskott-Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma. Nat Med. 2019;25:130-140 pubmed publisher |
| Zhang W, Li Q, Li D, Li J, Aki D, Liu Y. The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation. J Exp Med. 2018;215:3180-3193 pubmed publisher |
| Ng K, Yui M, Mehta A, Siu S, Irwin B, Pease S, et al. A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment. elife. 2018;7: pubmed publisher |
| James K, Cosway E, LUCAS B, White A, Parnell S, Carvalho Gaspar M, et al. Endothelial cells act as gatekeepers for LTβR-dependent thymocyte emigration. J Exp Med. 2018;215:2984-2993 pubmed publisher |
| Grigoryan A, Guidi N, Senger K, Liehr T, Soller K, Marka G, et al. LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells. Genome Biol. 2018;19:189 pubmed publisher |
| Hsu J, Dayaram T, Tovy A, De Braekeleer E, Jeong M, Wang F, et al. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy. Cell Stem Cell. 2018;23:700-713.e6 pubmed publisher |
| Fan X, Moltedo B, Mendoza A, Davydov A, Faire M, Mazutis L, et al. CD49b defines functionally mature Treg cells that survey skin and vascular tissues. J Exp Med. 2018;215:2796-2814 pubmed publisher |
| Chandra S, Gray J, Kiosses W, Khurana A, Hitomi K, Crosby C, et al. Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae. Nat Commun. 2018;9:4279 pubmed publisher |
| Lobo N, Zabala M, Qian D, Clarke M. Serially transplantable mammary epithelial cells express the Thy-1 antigen. Breast Cancer Res. 2018;20:121 pubmed publisher |
| Giambra V, Gusscott S, Gracias D, Song R, Lam S, Panelli P, et al. Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity. Cell Stem Cell. 2018;23:714-726.e7 pubmed publisher |
| Hamanaka S, Umino A, Sato H, Hayama T, Yanagida A, Mizuno N, et al. Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation. Stem Cell Reports. 2018;11:988-997 pubmed publisher |
| Charlesworth C, Camarena J, Cromer M, Vaidyanathan S, Bak R, Carte J, et al. Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting. Mol Ther Nucleic Acids. 2018;12:89-104 pubmed publisher |
| Albarrán Juárez J, Iring A, Wang S, Joseph S, Grimm M, Strilic B, et al. Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation. J Exp Med. 2018;215:2655-2672 pubmed publisher |
| Luo Y, Grötsch B, Hannemann N, Jimenez M, Ipseiz N, Uluçkan O, et al. Fra-2 Expression in Osteoblasts Regulates Systemic Inflammation and Lung Injury through Osteopontin. Mol Cell Biol. 2018;38: pubmed publisher |
| Koohy H, Bolland D, Matheson L, Schoenfelder S, Stellato C, Dimond A, et al. Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells. Genome Biol. 2018;19:126 pubmed publisher |
| Lau B, Huh K, Madero Marroquin R, De Marchi F, Lim Y, Wang Q, et al. Hedgehog/GLI1 activation leads to leukemic transformation of myelodysplastic syndrome in vivo and GLI1 inhibition results in antitumor activity. Oncogene. 2019;38:687-698 pubmed publisher |
| Walia M, Taylor S, Ho P, Martin T, Walkley C. Tolerance to sustained activation of the cAMP/Creb pathway activity in osteoblastic cells is enabled by loss of p53. Cell Death Dis. 2018;9:844 pubmed publisher |
| Lahvic J, Ammerman M, Li P, Blair M, Stillman E, Fast E, et al. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proc Natl Acad Sci U S A. 2018;115:9252-9257 pubmed publisher |
| Cunningham C, Hoppins S, Fink P. Cutting Edge: Glycolytic Metabolism and Mitochondrial Metabolism Are Uncoupled in Antigen-Activated CD8+ Recent Thymic Emigrants. J Immunol. 2018;201:1627-1632 pubmed publisher |
| Guo H, Barberi T, Suresh R, Friedman A. Progression from the Common Lymphoid Progenitor to B/Myeloid PreproB and ProB Precursors during B Lymphopoiesis Requires C/EBPα. J Immunol. 2018;201:1692-1704 pubmed publisher |
| Xing S, Shao P, Li F, Zhao X, Seo W, Wheat J, et al. Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity. J Exp Med. 2018;215:2211-2226 pubmed publisher |
| Kim H, Park M, Lee S, Park J, Lee H, Bae Y. Activation of formyl peptide receptor 2 by WKYMVm enhances emergency granulopoiesis through phospholipase C activity. BMB Rep. 2018;51:418-423 pubmed |
| Burke A, Sutherland B, Telford D, Morrow M, Sawyez C, Edwards J, et al. Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr-/- mice. J Lipid Res. 2018;59:1714-1728 pubmed publisher |
| Rogers M, Lamens K, Shafagati N, Johnson M, Oury T, Joyce S, et al. CD4+ Regulatory T Cells Exert Differential Functions during Early and Late Stages of the Immune Response to Respiratory Viruses. J Immunol. 2018;201:1253-1266 pubmed publisher |
| Gisterå A, Klement M, Polyzos K, Mailer R, Duhlin A, Karlsson M, et al. LDL-Reactive T Cells Regulate Plasma Cholesterol Levels and Development of Atherosclerosis in Humanized Hypercholesterolemic Mice. Circulation. 2018;: pubmed publisher |
| Bayindir Buchhalter I, Wolff G, Lerch S, Sijmonsma T, Schuster M, Gronych J, et al. Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors. EMBO Mol Med. 2018;10: pubmed publisher |
| Lam J, van den Bosch M, Wegrzyn J, Parker J, Ibrahim R, Slowski K, et al. miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling. Nat Commun. 2018;9:2418 pubmed publisher |
| Kirkling M, Cytlak U, Lau C, Lewis K, Resteu A, Khodadadi Jamayran A, et al. Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells. Cell Rep. 2018;23:3658-3672.e6 pubmed publisher |
| Petukhov V, Guo J, Baryawno N, Severe N, Scadden D, Samsonova M, et al. dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments. Genome Biol. 2018;19:78 pubmed publisher |
| Webster B, Werneke S, Zafirova B, This S, Coléon S, Decembre E, et al. Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses. elife. 2018;7: pubmed publisher |
| Jensen C, Åhsberg J, Sommarin M, Strid T, Somasundaram R, Okuyama K, et al. Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis. J Exp Med. 2018;215:1947-1963 pubmed publisher |
| Alonso Martin S, Aurade F, Mademtzoglou D, Rochat A, Zammit P, Relaix F. SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity. elife. 2018;7: pubmed publisher |
| Liu T, Kong W, Tang X, Xu M, Wang Q, Zhang B, et al. The transcription factor Zfp90 regulates the self-renewal and differentiation of hematopoietic stem cells. Cell Death Dis. 2018;9:677 pubmed publisher |
| Liu Y, Huang H, Zhou S, Tian H, Li P. Excessive Iron Availability Caused by Disorders of Interleukin-10 and Interleukin-22 Contributes to High Altitude Polycythemia. Front Physiol. 2018;9:548 pubmed publisher |
| Ghanem L, Kromer A, Silverman I, Ji X, Gazzara M, Nguyen N, et al. Poly(C)-Binding Protein Pcbp2 Enables Differentiation of Definitive Erythropoiesis by Directing Functional Splicing of the Runx1 Transcript. Mol Cell Biol. 2018;38: pubmed publisher |
| Niland S, Komljenovic D, Macas J, Bracht T, Bauerle T, Liebner S, et al. Rhodocetin-αβ selectively breaks the endothelial barrier of the tumor vasculature in HT1080 fibrosarcoma and A431 epidermoid carcinoma tumor models. Oncotarget. 2018;9:22406-22422 pubmed publisher |
| Chen Y, Qin X, An Q, Yi J, Feng F, Yin D, et al. Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes. EBioMedicine. 2018;32:31-42 pubmed publisher |
| Daenthanasanmak A, Wu Y, Iamsawat S, Nguyen H, Bastian D, Zhang M, et al. PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity. J Clin Invest. 2018;128:2787-2801 pubmed publisher |
| Mitchell K, Barreyro L, Todorova T, Taylor S, Antony Debré I, Narayanagari S, et al. IL1RAP potentiates multiple oncogenic signaling pathways in AML. J Exp Med. 2018;215:1709-1727 pubmed publisher |
| Thomson C, van de Pavert S, Stakenborg M, Labeeuw E, Matteoli G, Mowat A, et al. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators. J Immunol. 2018;201:215-229 pubmed publisher |
| Thompson T, Jackson B, Li P, Wang J, Kim A, Huang K, et al. Tumor-derived CSF-1 induces the NKG2D ligand RAE-1δ on tumor-infiltrating macrophages. elife. 2018;7: pubmed publisher |
| Shi X, Kitano A, Jiang Y, Luu V, Hoegenauer K, Nakada D. Clonal expansion and myeloid leukemia progression modeled by multiplex gene editing of murine hematopoietic progenitor cells. Exp Hematol. 2018;64:33-44.e5 pubmed publisher |
| Cheung L, Tickner J, Hughes A, Skut P, Howlett M, Foley B, et al. New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment. Leukemia. 2018;32:2326-2338 pubmed publisher |
| Lee J, Wang Z, Sambo D, Bunting K, Pallas D. Global loss of leucine carboxyl methyltransferase-1 causes severe defects in fetal liver hematopoiesis. J Biol Chem. 2018;293:9636-9650 pubmed publisher |
| Huang N, Lin Y, Lin C, Pishesha N, Lewis C, Freinkman E, et al. Enhanced phosphocholine metabolism is essential for terminal erythropoiesis. Blood. 2018;: pubmed publisher |
| Zhang Y, Li L, Yu C, Senyuk V, Li F, Quigley J, et al. miR-9 upregulation leads to inhibition of erythropoiesis by repressing FoxO3. Sci Rep. 2018;8:6519 pubmed publisher |
| Salomè M, Magee A, Yalla K, Chaudhury S, Sarrou E, Carmody R, et al. A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling. Cell Death Dis. 2018;9:443 pubmed publisher |
| Sampath S, Sampath S, Ho A, Corbel S, Millstone J, Lamb J, et al. Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M. Nat Commun. 2018;9:1531 pubmed publisher |
| Griffin C, Eter L, Lanzetta N, Abrishami S, Varghese M, McKernan K, et al. TLR4, TRIF, and MyD88 are essential for myelopoiesis and CD11c+ adipose tissue macrophage production in obese mice. J Biol Chem. 2018;293:8775-8786 pubmed publisher |
| Xia P, Wang S, Ye B, Du Y, Li C, Xiong Z, et al. A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion. Immunity. 2018;48:688-701.e7 pubmed publisher |
| Zhou Y, Wang W, Zhao C, Wang Y, Wu H, Sun X, et al. Prostaglandin E2 Inhibits Group 2 Innate Lymphoid Cell Activation and Allergic Airway Inflammation Through E-Prostanoid 4-Cyclic Adenosine Monophosphate Signaling. Front Immunol. 2018;9:501 pubmed publisher |
| Dutton E, Camelo A, Sleeman M, Herbst R, Carlesso G, Belz G, et al. Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity. Wellcome Open Res. 2017;2:117 pubmed publisher |
| Durai V, Bagadia P, Briseño C, Theisen D, Iwata A, Davidson J, et al. Altered compensatory cytokine signaling underlies the discrepancy between Flt3-/- and Flt3l-/- mice. J Exp Med. 2018;215:1417-1435 pubmed publisher |
| Seike M, Omatsu Y, Watanabe H, Kondoh G, Nagasawa T. Stem cell niche-specific Ebf3 maintains the bone marrow cavity. Genes Dev. 2018;32:359-372 pubmed publisher |
| Khajuria R, Munschauer M, Ulirsch J, Fiorini C, Ludwig L, McFarland S, et al. Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis. Cell. 2018;173:90-103.e19 pubmed publisher |
| Kim G, Gu M, Kim S, Ko K, Kye Y, Kim C, et al. Transcription Factor KLF10 Constrains IL-17-Committed Vγ4+ γδ T Cells. Front Immunol. 2018;9:196 pubmed publisher |
| Takai K, Drain A, Lawson D, Littlepage L, Karpuj M, Kessenbrock K, et al. Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers. Genes Dev. 2018;32:244-257 pubmed publisher |
| Marroncelli N, Bianchi M, Bertin M, Consalvi S, Saccone V, De Bardi M, et al. HDAC4 regulates satellite cell proliferation and differentiation by targeting P21 and Sharp1 genes. Sci Rep. 2018;8:3448 pubmed publisher |
| Zhang H, Li H, Hillmer E, Zhao Y, Chrisikos T, Hu H, et al. Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis. Proc Natl Acad Sci U S A. 2018;115:E2311-E2319 pubmed publisher |
| Kim I, Kim K, Lee E, Oh D, Park C, Park S, et al. Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality. J Exp Med. 2018;215:963-983 pubmed publisher |
| Lu Z, Hong C, Kong G, Assumpção A, Ong I, Bresnick E, et al. Polycomb Group Protein YY1 Is an Essential Regulator of Hematopoietic Stem Cell Quiescence. Cell Rep. 2018;22:1545-1559 pubmed publisher |
| Russi A, Ebel M, Yang Y, Brown M. Male-specific IL-33 expression regulates sex-dimorphic EAE susceptibility. Proc Natl Acad Sci U S A. 2018;115:E1520-E1529 pubmed publisher |
| Tenno M, Kojo S, Lawir D, Hess I, Shiroguchi K, Ebihara T, et al. Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors. J Exp Med. 2018;215:595-610 pubmed publisher |
| Christ A, Günther P, Lauterbach M, Duewell P, Biswas D, Pelka K, et al. Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell. 2018;172:162-175.e14 pubmed publisher |
| Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher |
| Kostrzewski T, Borg A, Meng Y, Filipovic I, Male V, Wack A, et al. Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development. J Immunol. 2018;200:1370-1381 pubmed publisher |
| Serrano López J, Nattamai K, Pease N, Shephard M, Wellendorf A, Sertorio M, et al. Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors. Exp Hematol. 2018;59:40-50.e3 pubmed publisher |
| Mumau M, Vanderbeck A, Lynch E, Golec S, Emerson S, Punt J. Identification of a Multipotent Progenitor Population in the Spleen That Is Regulated by NR4A1. J Immunol. 2018;200:1078-1087 pubmed publisher |
| Kunimoto H, Meydan C, Nazir A, Whitfield J, Shank K, Rapaport F, et al. Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity. Cancer Cell. 2018;33:44-59.e8 pubmed publisher |
| Wang J, Saijo K, Skola D, Jin C, Ma Q, Merkurjev D, et al. Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock. Proc Natl Acad Sci U S A. 2018;115:E244-E252 pubmed publisher |
| Ibitokou S, Dillon B, Sinha M, Szczesny B, Delgadillo A, Reda Abdelrahman D, et al. Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection. J Immunol. 2018;200:643-656 pubmed publisher |
| Zhao B, Mei Y, Cao L, Zhang J, Sumagin R, Yang J, et al. Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms. J Clin Invest. 2018;128:125-140 pubmed publisher |
| Chamberlin T, D Amato J, Arendt L. Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity. Breast Cancer Res. 2017;19:128 pubmed publisher |
| Harly C, Cam M, Kaye J, Bhandoola A. Development and differentiation of early innate lymphoid progenitors. J Exp Med. 2018;215:249-262 pubmed publisher |
| Hindi S, Shin J, Gallot Y, Straughn A, Simionescu Bankston A, Hindi L, et al. MyD88 promotes myoblast fusion in a cell-autonomous manner. Nat Commun. 2017;8:1624 pubmed publisher |
| Haber A, Biton M, Rogel N, Herbst R, Shekhar K, Smillie C, et al. A single-cell survey of the small intestinal epithelium. Nature. 2017;551:333-339 pubmed publisher |
| Singh P, Hoggatt J, Kamocka M, Mohammad K, Saunders M, Li H, et al. Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells. J Clin Invest. 2017;127:4527-4540 pubmed publisher |
| Sala M, Chen C, Zhang Q, Do Umehara H, Wu W, Misharin A, et al. JNK2 up-regulates hypoxia-inducible factors and contributes to hypoxia-induced erythropoiesis and pulmonary hypertension. J Biol Chem. 2018;293:271-284 pubmed publisher |
| Tsai F, Homan P, Agrawal H, Misharin A, Abdala Valencia H, Haines G, et al. Bim suppresses the development of SLE by limiting myeloid inflammatory responses. J Exp Med. 2017;214:3753-3773 pubmed publisher |
| Yu W, Goncalves K, Li S, Kishikawa H, Sun G, Yang H, et al. Plexin-B2 Mediates Physiologic and Pathologic Functions of Angiogenin. Cell. 2017;171:849-864.e25 pubmed publisher |
| McGarvey A, Rybtsov S, Souilhol C, Tamagno S, Rice R, Hills D, et al. A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation. J Exp Med. 2017;214:3731-3751 pubmed publisher |
| Wang Q, Racine J, Ratiu J, Wang S, Ettinger R, Wasserfall C, et al. Transient BAFF Blockade Inhibits Type 1 Diabetes Development in Nonobese Diabetic Mice by Enriching Immunoregulatory B Lymphocytes Sensitive to Deletion by Anti-CD20 Cotherapy. J Immunol. 2017;199:3757-3770 pubmed publisher |
| Mello S, Valente L, Raj N, Seoane J, Flowers B, McClendon J, et al. A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer. Cancer Cell. 2017;32:460-473.e6 pubmed publisher |
| Catalan Dibene J, Vazquez M, Luu V, Nuccio S, Karimzadeh A, Kastenschmidt J, et al. Identification of IL-40, a Novel B Cell-Associated Cytokine. J Immunol. 2017;199:3326-3335 pubmed publisher |
| Kollek M, Voigt G, Molnar C, Murad F, Bertele D, Krombholz C, et al. Transient apoptosis inhibition in donor stem cells improves hematopoietic stem cell transplantation. J Exp Med. 2017;214:2967-2983 pubmed publisher |
| Heraud Farlow J, Chalk A, Linder S, Li Q, Taylor S, White J, et al. Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis. Genome Biol. 2017;18:166 pubmed publisher |
| Noel J, Ramser B, Cancelas J, McCormack F, Gardner J. Thermal injury of the skin induces G-CSF-dependent attenuation of EPO-mediated STAT signaling and erythroid differentiation arrest in mice. Exp Hematol. 2017;56:16-30 pubmed publisher |
| Gao X, Lee H, Li W, Platt R, Barrasa M, Ma Q, et al. Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation. Proc Natl Acad Sci U S A. 2017;114:10107-10112 pubmed publisher |
| Wang Y, Jin Y, Mäe M, Zhang Y, Ortsäter H, Betsholtz C, et al. Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity. Development. 2017;144:3590-3601 pubmed publisher |
| Mitroulis I, Chen L, Singh R, Kourtzelis I, Economopoulou M, Kajikawa T, et al. Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche. J Clin Invest. 2017;127:3624-3639 pubmed publisher |
| Eksmond U, Jenkins B, Merkenschlager J, Mothes W, Stoye J, Kassiotis G. Mutation of the Putative Immunosuppressive Domain of the Retroviral Envelope Glycoprotein Compromises Infectivity. J Virol. 2017;91: pubmed publisher |
| Pei W, Feyerabend T, Rössler J, Wang X, Postrach D, Busch K, et al. Polylox barcoding reveals haematopoietic stem cell fates realized in vivo. Nature. 2017;548:456-460 pubmed publisher |
| Chang S, Kohlgruber A, Mizoguchi F, Michelet X, Wolf B, Wei K, et al. Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes. J Clin Invest. 2017;127:3300-3312 pubmed publisher |
| Ghosh D, Brown S, Stumhofer J. IL-17 Promotes Differentiation of Splenic LSK- Lymphoid Progenitors into B Cells following Plasmodium yoelii Infection. J Immunol. 2017;199:1783-1795 pubmed publisher |
| Webb L, Lundie R, Borger J, Brown S, Connor L, Cartwright A, et al. Type I interferon is required for T helper (Th) 2 induction by dendritic cells. EMBO J. 2017;36:2404-2418 pubmed publisher |
| Gibb D, Liu J, Natarajan P, Santhanakrishnan M, Madrid D, Eisenbarth S, et al. Type I IFN Is Necessary and Sufficient for Inflammation-Induced Red Blood Cell Alloimmunization in Mice. J Immunol. 2017;199:1041-1050 pubmed publisher |
| Li L, Sheng Y, Li W, Hu C, Mittal N, Tohyama K, et al. β-Catenin Is a Candidate Therapeutic Target for Myeloid Neoplasms with del(5q). Cancer Res. 2017;77:4116-4126 pubmed publisher |
| Kim E, Cheng Y, Bolton Gillespie E, Cai X, Ma C, Tarangelo A, et al. Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression. J Exp Med. 2017;214:1901-1912 pubmed publisher |
| Minutti C, Jackson Jones L, Garcia Fojeda B, Knipper J, Sutherland T, Logan N, et al. Local amplifiers of IL-4R?-mediated macrophage activation promote repair in lung and liver. Science. 2017;356:1076-1080 pubmed publisher |
| Lim J, Ibaseta A, Fischer M, Cancilla B, O Young G, Cristea S, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. 2017;545:360-364 pubmed publisher |
| Tammela T, Sanchez Rivera F, Cetinbas N, Wu K, Joshi N, Helenius K, et al. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature. 2017;545:355-359 pubmed publisher |
| Xu C, Lee T, Sakurai N, Krchma K, Liu F, Li D, et al. ETV2/ER71 regulates hematopoietic regeneration by promoting hematopoietic stem cell proliferation. J Exp Med. 2017;214:1643-1653 pubmed publisher |
| Ratiu J, Racine J, Hasham M, Wang Q, Branca J, Chapman H, et al. Genetic and Small Molecule Disruption of the AID/RAD51 Axis Similarly Protects Nonobese Diabetic Mice from Type 1 Diabetes through Expansion of Regulatory B Lymphocytes. J Immunol. 2017;198:4255-4267 pubmed publisher |
| Schneider R, Mullally A, Dugourd A, Peisker F, Hoogenboezem R, van Strien P, et al. Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target. Cell Stem Cell. 2017;20:785-800.e8 pubmed publisher |
| Hérault A, Binnewies M, Leong S, Calero Nieto F, Zhang S, Kang Y, et al. Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis. Nature. 2017;544:53-58 pubmed publisher |
| Xiong G, Hindi S, Mann A, Gallot Y, Bohnert K, Cavener D, et al. The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration. elife. 2017;6: pubmed publisher |
| Lefrançais E, Ortiz Muñoz G, Caudrillier A, Mallavia B, Liu F, Sayah D, et al. The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors. Nature. 2017;544:105-109 pubmed publisher |
| Ho C, Chhabra A, Starkl P, Schnorr P, Wilmes S, Moraga I, et al. Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling. Cell. 2017;168:1041-1052.e18 pubmed publisher |
| Ho T, Warr M, Adelman E, Lansinger O, Flach J, Verovskaya E, et al. Autophagy maintains the metabolism and function of young and old stem cells. Nature. 2017;543:205-210 pubmed publisher |
| Li H, Liu P, Xu S, Li Y, Dekker J, Li B, et al. FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging. J Clin Invest. 2017;127:1241-1253 pubmed publisher |
| Hwang I, Park C, Harrison K, Kehrl J. Normal Thymocyte Egress, T Cell Trafficking, and CD4+ T Cell Homeostasis Require Interactions between RGS Proteins and Gαi2. J Immunol. 2017;198:2721-2734 pubmed publisher |
| Zhu H, Kwak H, Liu P, Bajrami B, Xu Y, Park S, et al. Reactive Oxygen Species-Producing Myeloid Cells Act as a Bone Marrow Niche for Sterile Inflammation-Induced Reactive Granulopoiesis. J Immunol. 2017;198:2854-2864 pubmed publisher |
| Wu J, Sun L, Li H, Shen H, Zhai W, Yu Z, et al. Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory phenotype. J Neuroinflammation. 2017;14:36 pubmed publisher |
| Bernitz J, Daniel M, Fstkchyan Y, Moore K. Granulocyte colony-stimulating factor mobilizes dormant hematopoietic stem cells without proliferation in mice. Blood. 2017;129:1901-1912 pubmed publisher |
| Li H, Choesang T, Bao W, Chen H, Feola M, Garcia Santos D, et al. Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice. Blood. 2017;129:1514-1526 pubmed publisher |
| Zhang Y, Zhang J, An W, Wan Y, Ma S, Yin J, et al. Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation. Nucleic Acids Res. 2017;45:657-671 pubmed publisher |
| Yu L, Takai J, Otsuki A, Katsuoka F, Suzuki M, Katayama S, et al. Derepression of the DNA Methylation Machinery of the Gata1 Gene Triggers the Differentiation Cue for Erythropoiesis. Mol Cell Biol. 2017;37: pubmed publisher |
| Opata M, Stephens R. Chronic Plasmodium chabaudi Infection Generates CD4 Memory T Cells with Increased T Cell Receptor Sensitivity but Poor Secondary Expansion and Increased Apoptosis. Infect Immun. 2017;85: pubmed publisher |
| Yang J, Tanaka Y, Seay M, Li Z, Jin J, Garmire L, et al. Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors. Nucleic Acids Res. 2017;45:1281-1296 pubmed publisher |
| Gadani S, Smirnov I, Smith A, Overall C, Kipnis J. Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury. J Exp Med. 2017;214:285-296 pubmed publisher |
| Kandalla P, Sarrazin S, Molawi K, Berruyer C, Redelberger D, Favel A, et al. M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation. J Exp Med. 2016;213:2269-2279 pubmed |
| Puccetti M, Fischer M, Arrate M, Boyd K, Duszynski R, Bétous R, et al. Defective replication stress response inhibits lymphomagenesis and impairs lymphocyte reconstitution. Oncogene. 2017;36:2553-2564 pubmed publisher |
| Zhang J, McCastlain K, Yoshihara H, Xu B, Chang Y, Churchman M, et al. Deregulation of DUX4 and ERG in acute lymphoblastic leukemia. Nat Genet. 2016;48:1481-1489 pubmed publisher |
| Ishida T, Takahashi S, Lai C, Nojima M, Yamamoto R, Takeuchi E, et al. Multiple allogeneic progenitors in combination function as a unit to support early transient hematopoiesis in transplantation. J Exp Med. 2016;213:1865-80 pubmed publisher |
| Wilhelm C, Harrison O, Schmitt V, Pelletier M, Spencer S, Urban J, et al. Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infection. J Exp Med. 2016;213:1409-18 pubmed publisher |
| Rowe R, Wang L, Coma S, Han A, Mathieu R, Pearson D, et al. Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis. J Exp Med. 2016;213:1497-512 pubmed publisher |
| Su Q, Zhang B, Zhang L, Dang T, Rowley D, Ittmann M, et al. Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer. Oncogene. 2017;36:618-627 pubmed publisher |
| Welte T, Kim I, Tian L, Gao X, Wang H, Li J, et al. Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 2016;18:632-44 pubmed publisher |
| Avila A, Illing A, Becker F, Maerz L, Morita Y, Philipp M, et al. Xpg limits the expansion of haematopoietic stem and progenitor cells after ionising radiation. Nucleic Acids Res. 2016;44:6252-61 pubmed publisher |
| Valcourt U, Carthy J, Okita Y, Alcaraz L, Kato M, Thuault S, et al. Analysis of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor β. Methods Mol Biol. 2016;1344:147-81 pubmed publisher |
| Huang Y, Guo L, Qiu J, Chen X, Hu Li J, Siebenlist U, et al. IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells. Nat Immunol. 2015;16:161-9 pubmed publisher |
| Steinke F, Yu S, Zhou X, He B, Yang W, Zhou B, et al. TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells. Nat Immunol. 2014;15:646-656 pubmed publisher |
| Mahmud S, Manlove L, Schmitz H, Xing Y, Wang Y, Owen D, et al. Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells. Nat Immunol. 2014;15:473-81 pubmed publisher |
| Lucas D, Scheiermann C, Chow A, Kunisaki Y, Bruns I, Barrick C, et al. Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration. Nat Med. 2013;19:695-703 pubmed publisher |
| Li Q, Zhou X, Shi Y, Li J, Zheng L, Cui L, et al. In vivo tracking and comparison of the therapeutic effects of MSCs and HSCs for liver injury. PLoS ONE. 2013;8:e62363 pubmed publisher |
| Petropoulos K, Arseni N, Schessl C, Stadler C, Rawat V, Deshpande A, et al. A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis. J Exp Med. 2008;205:515-22 pubmed publisher |
| O Connell R, Rao D, Chaudhuri A, Boldin M, Taganov K, Nicoll J, et al. Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med. 2008;205:585-94 pubmed publisher |
| Labi V, Erlacher M, Kiessling S, Manzl C, Frenzel A, O Reilly L, et al. Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development. J Exp Med. 2008;205:641-55 pubmed publisher |
| Delano M, Scumpia P, Weinstein J, Coco D, Nagaraj S, Kelly Scumpia K, et al. MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med. 2007;204:1463-74 pubmed |
| Porcellini S, Traggiai E, Schenk U, Ferrera D, Matteoli M, Lanzavecchia A, et al. Regulation of peripheral T cell activation by calreticulin. J Exp Med. 2006;203:461-71 pubmed |
| Matsubara A, Iwama A, Yamazaki S, Furuta C, Hirasawa R, Morita Y, et al. Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development. J Exp Med. 2005;202:1483-92 pubmed |
| Benz C, Bleul C. A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision. J Exp Med. 2005;202:21-31 pubmed |
| Massengale M, Wagers A, Vogel H, Weissman I. Hematopoietic cells maintain hematopoietic fates upon entering the brain. J Exp Med. 2005;201:1579-89 pubmed |
| Rifa i M, Kawamoto Y, Nakashima I, Suzuki H. Essential roles of CD8+CD122+ regulatory T cells in the maintenance of T cell homeostasis. J Exp Med. 2004;200:1123-34 pubmed |
| Shibayama H, Takai E, Matsumura I, Kouno M, Morii E, Kitamura Y, et al. Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis. J Exp Med. 2004;199:581-92 pubmed |
| Cobas M, Wilson A, Ernst B, Mancini S, MacDonald H, Kemler R, et al. Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. J Exp Med. 2004;199:221-9 pubmed |
| Ueda Y, Yang K, Foster S, Kondo M, Kelsoe G. Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression. J Exp Med. 2004;199:47-58 pubmed |
| Karsunky H, Merad M, Cozzio A, Weissman I, Manz M. Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J Exp Med. 2003;198:305-13 pubmed |
| Lambert J, Liu M, Colvin G, Dooner M, McAuliffe C, Becker P, et al. Marrow stem cells shift gene expression and engraftment phenotype with cell cycle transit. J Exp Med. 2003;197:1563-72 pubmed |
| Iwasaki Arai J, Iwasaki H, Miyamoto T, Watanabe S, Akashi K. Enforced granulocyte/macrophage colony-stimulating factor signals do not support lymphopoiesis, but instruct lymphoid to myelomonocytic lineage conversion. J Exp Med. 2003;197:1311-22 pubmed |
| Rodewald H, Waskow C, Haller C. Essential requirement for c-kit and common gamma chain in thymocyte development cannot be overruled by enforced expression of Bcl-2. J Exp Med. 2001;193:1431-7 pubmed |
