I-Ek Monoclonal Antibody (14-4-4S) | Invitrogen MA1-70066 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

I-Ek Monoclonal Antibody (14-4-4S)

catalog :

MA1-70066

quantity :

250 µg

price :

US 414

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

14-4-4S

The same clone is also sold as:

BioLegend: 110211, 110205

reactivity :

mouse

application :

flow cytometry

citations: 1

Reference
Krishnan B, Massilamany C, Basavalingappa R, Gangaplara A, Rajasekaran R, Afzal M, et al. Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice. J Immunol. 2018;200:523-537 pubmed publisher

product information

Product Type :

Antibody

Product Name :

I-Ek Monoclonal Antibody (14-4-4S)

Catalog # :

MA1-70066

Quantity :

250 µg

Price :

US 414

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 µg/1 million cells

Species :

Mouse

Clone :

14-4-4S

Isotype :

IgG2a, kappa

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Immunogen :

C3H.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/1 million cells

Aliases :

AI323765; cell surface glycoprotein; E-alpha-f; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2 class II histocompatibility antigen, I-E beta chain; H-2Ea; H2-Ea; H2-Ea-ps; H2Eb; H-2Eb; H2-Eb1; H2-IE-alpha; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; histocompatibility 2, class II antigen E beta; Ia3; Ia-3; Ia4; Ia-4; I-E alpha MHC class II; I-E beta MHC class II; I-Ealpha; major histocompatibility complex H-2E beta chain; MGC117888; MHC class II antigen E alpha; MHC class II IE-b; MHC class II protein; MHC H2-IE-beta cell surface glycoprotein