product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD90 Monoclonal Antibody (5a-8)
catalog :
MA1-70062
quantity :
250 ug
price :
US 474.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5a-8
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section, other
more info or order :
citations: 23
| Published Application/Species/Sample/Dilution | Reference |
|---|---|
| |
| King S, Knorn A, Ohnmacht C, Voehringer D. Accumulation of effector CD4 T cells during type 2 immune responses is negatively regulated by Stat6. J Immunol. 2008;180:754-63 pubmed
|
| Hayakawa I, Tedder T, Zhuang Y. B-lymphocyte depletion ameliorates Sjögren's syndrome in Id3 knockout mice. Immunology. 2007;122:73-9 pubmed
|
| Burster T, Giffon T, Dahl M, Björck P, Bogyo M, Weber E, et al. Influenza A virus elevates active cathepsin B in primary murine DC. Int Immunol. 2007;19:645-55 pubmed
|
| Garcia Ojeda M, Dejbakhsh Jones S, Chatterjea Matthes D, Mukhopadhyay A, BitMansour A, Weissman I, et al. Stepwise development of committed progenitors in the bone marrow that generate functional T cells in the absence of the thymus. J Immunol. 2005;175:4363-73 pubmed
|
| Hamaguchi Tsuru E, Nobumoto A, Hirose N, Kataoka S, Fujikawa Adachi K, Furuya M, et al. Development and functional analysis of eosinophils from murine embryonic stem cells. Br J Haematol. 2004;124:819-27 pubmed
|
| Germeraad W, Kawamoto H, Itoi M, Jiang Y, Amagai T, Katsura Y, et al. Development of thymic microenvironments in vitro is oxygen-dependent and requires permanent presence of T-cell progenitors. J Histochem Cytochem. 2003;51:1225-35 pubmed
|
| Chatterjea Matthes D, Garcia Ojeda M, Dejbakhsh Jones S, Jerabek L, Manz M, Weissman I, et al. Early defect prethymic in bone marrow T cell progenitors in athymic nu/nu mice. J Immunol. 2003;171:1207-15 pubmed
|
| Hoffmann P, Ermann J, Edinger M, Fathman C, Strober S. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med. 2002;196:389-99 pubmed
|
| Lan F, Zeng D, Higuchi M, Huie P, Higgins J, Strober S. Predominance of NK1.1+TCR alpha beta+ or DX5+TCR alpha beta+ T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: "natural suppressor" cells. J Immunol. 2001;167:2087-96 pubmed
|
| Dejbakhsh Jones S, Garcia Ojeda M, Chatterjea Matthes D, Zeng D, Strober S. Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway. Proc Natl Acad Sci U S A. 2001;98:7455-60 pubmed
|
| Lan F, Zeng D, Huie P, Higgins J, Strober S. Allogeneic bone marrow cells that facilitate complete chimerism and eliminate tumor cells express both CD8 and T-cell antigen receptor-alphabeta. Blood. 2001;97:3458-65 pubmed
|
| Telford W, Moss M, Morseman J, Allnutt F. Cryptomonad algal phycobiliproteins as fluorochromes for extracellular and intracellular antigen detection by flow cytometry. Cytometry. 2001;44:16-23 pubmed
|
| Ohmura K, Kawamoto H, Lu M, Ikawa T, Ozaki S, Nakao K, et al. Immature multipotent hemopoietic progenitors lacking long-term bone marrow-reconstituting activity in the aorta-gonad-mesonephros region of murine day 10 fetuses. J Immunol. 2001;166:3290-6 pubmed
|
| Rodewald H, Brocker T, Haller C. Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice. Proc Natl Acad Sci U S A. 1999;96:15068-73 pubmed
|
| Dejbakhsh Jones S, Strober S. Identification of an early T cell progenitor for a pathway of T cell maturation in the bone marrow. Proc Natl Acad Sci U S A. 1999;96:14493-8 pubmed
|
| Ikawa T, Kawamoto H, Fujimoto S, Katsura Y. Commitment of common T/Natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay. J Exp Med. 1999;190:1617-26 pubmed
|
| Ohmura K, Kawamoto H, Fujimoto S, Ozaki S, Nakao K, Katsura Y. Emergence of T, B, and myeloid lineage-committed as well as multipotent hemopoietic progenitors in the aorta-gonad-mesonephros region of day 10 fetuses of the mouse. J Immunol. 1999;163:4788-95 pubmed
|
| Kawamoto H, Ohmura K, Fujimoto S, Katsura Y. Emergence of T cell progenitors without B cell or myeloid differentiation potential at the earliest stage of hematopoiesis in the murine fetal liver. J Immunol. 1999;162:2725-31 pubmed
|
| Barrat F, Lesourd B, Louise A, Boulouis H, Vincent Naulleau S, Thibault D, et al. Surface antigen expression in spleen cells of C57B1/6 mice during ageing: influence of sex and parity. Clin Exp Immunol. 1997;107:593-600 pubmed
|
| Hattori N, Kawamoto H, Katsura Y. Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells. J Exp Med. 1996;184:1901-8 pubmed
|
| Pear W, Aster J, Scott M, Hasserjian R, Soffer B, Sklar J, et al. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med. 1996;183:2283-91 pubmed
|
| Rathmell J, Goodnow C. Effects of the lpr mutation on elimination and inactivation of self-reactive B cells. J Immunol. 1994;153:2831-42 pubmed
|
product information
Product Type :
Antibody
Product Name :
CD90 Monoclonal Antibody (5a-8)
Catalog # :
MA1-70062
Quantity :
250 ug
Price :
US 474.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Mouse
Applications :
Cytotoxicity Assay: Assay-dependent, Flow Cytometry: 1 ug/1 million cells, Immunohistochemistry (Frozen): Assay-dependent
Species :
Mouse
Clone :
5a-8
Isotype :
IgG2b
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.
Immunogen :
CBA/J.
Format :
Liquid
Applications w/Dilutions :
Cytotoxicity Assay: Assay-dependent, Flow Cytometry: 1 ug/1 million cells, Immunohistochemistry (Frozen): Assay-dependent
Aliases :
CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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