OX40 Monoclonal Antibody (OX40) | Invitrogen MA1-70020 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

OX40 Monoclonal Antibody (OX40)

catalog :

MA1-70020

quantity :

250 ug

price :

US 276.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OX40

reactivity :

rat, cat

application :

immunohistochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; cat	Tochikura T, Naito Y, Kozutsumi Y, Hohdatsu T. Induction of feline immunodeficiency virus from a chronically infected feline T-lymphocyte cell line. Res Vet Sci. 2012;92:327-32 pubmed publisher
flow cytometry; cat	Tochikura T, Motokawa K, Naito Y, Kozutsumi Y, Tanabe Tochikura A, Hohdatsu T. Differential CXCR4 expression and function in subpopulations of the feline lymphoma cell line 3201 susceptible to feline immunodeficiency virus. J Feline Med Surg. 2010;12:269-77 pubmed publisher
	Kendirli A, de la Rosa C, L xe4 mmle K, Eglseer K, Bauer I, Kavaka V, et al. A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model. Nat Neurosci. 2023;26:1713-1725 pubmed publisher
	Lee J, Park N, Park J, Kaplan B, Pruett S, Park J, et al. Induction of Immunosuppressive CD8+CD25+FOXP3+ Regulatory T Cells by Suboptimal Stimulation with Staphylococcal Enterotoxin C1. J Immunol. 2018;200:669-680 pubmed publisher
	Pattarini L, Trichot C, Bogiatzi S, Grandclaudon M, Meller S, Keuylian Z, et al. TSLP-activated dendritic cells induce human T follicular helper cell differentiation through OX40-ligand. J Exp Med. 2017;214:1529-1546 pubmed publisher
	Nagase H, Takeoka T, Urakawa S, Morimoto Okazawa A, Kawashima A, Iwahori K, et al. ICOS+ Foxp3+ TILs in gastric cancer are prognostic markers and effector regulatory T cells associated with Helicobacter pylori. Int J Cancer. 2017;140:686-695 pubmed publisher
	Triplett T, Tucker C, Triplett K, Alderman Z, Sun L, Ling L, et al. STAT3 Signaling Is Required for Optimal Regression of Large Established Tumors in Mice Treated with Anti-OX40 and TGFÎ² Receptor Blockade. Cancer Immunol Res. 2015;3:526-35 pubmed publisher
	Hirota K, Hashimoto M, Yoshitomi H, Tanaka S, Nomura T, Yamaguchi T, et al. T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis. J Exp Med. 2007;204:41-7 pubmed
	Mikolajczak S, Ma B, Yoshida T, Yoshida R, Kelvin D, Ochi A. The modulation of CD40 ligand signaling by transmembrane CD28 splice variant in human T cells. J Exp Med. 2004;199:1025-31 pubmed

product information

Product Type :

Antibody

Product Name :

OX40 Monoclonal Antibody (OX40)

Catalog # :

MA1-70020

Quantity :

250 ug

Price :

US 276.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Rat

Applications :

Flow Cytometry: 1 ug/1 million cells, Immunohistochemistry (Frozen): Assay-dependent

Species :

Rat

Clone :

OX40

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

OX40 is a protein receptor found on the surface of T cells, a type of white blood cell that plays a crucial role in the immune system. When activated, OX40 promotes the proliferation and survival of T cells, leading to a stronger immune response against cancer cells and infectious agents. OX40 agonists, which are drugs that activate OX40, have shown promising results in preclinical and clinical studies as a potential immunotherapy for cancer. They can enhance the efficacy of other cancer treatments such as chemotherapy and checkpoint inhibitors, and may also have applications in autoimmune diseases and allergies.

Immunogen :

Phytohaemagglutinin-activated rat lymph node cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/1 million cells, Immunohistochemistry (Frozen): Assay-dependent

Aliases :

ACT35; ACT35 antigen; ATC35 antigen; CD134; CD134 antigen; IMD16; Ly-70; lymphoid activation antigene ACT35; MRC OX40; Ox40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 receptor; TNF receptor superfamily member 4; Tnfrsf4; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4; tumor necrosis factor superfamily, member 4; Txgp1; Txgp1l

more info or order :

Invitrogen product webpage