Prolactin Receptor Monoclonal Antibody (T6) | Invitrogen MA1-611 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Prolactin Receptor Monoclonal Antibody (T6)

catalog :

MA1-611

quantity :

100 ug

price :

US 451.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; human	Schaffler A, Binart N, Scholmerich J, Büchler C. Hypothesis paper Brain talks with fat--evidence for a hypothalamic-pituitary-adipose axis?. Neuropeptides. 2005;39:363-7 pubmed
	Egli M, Bertram R, Toporikova N, Sellix M, Blanco W, Freeman M. Prolactin secretory rhythm of mated rats induced by a single injection of oxytocin. Am J Physiol Endocrinol Metab. 2006;290:E566-72 pubmed
	Gagnerault M, Touraine P, Savino W, Kelly P, Dardenne M. Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations. J Immunol. 1993;150:5673-81 pubmed
	Rui H, Lebrun J, Kirken R, Kelly P, Farrar W. JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization. Endocrinology. 1994;135:1299-306 pubmed
	Okamura H, Zachwieja J, Raguet S, Kelly P. Characterization and applications of monoclonal antibodies to the prolactin receptor. Endocrinology. 1989;124:2499-508 pubmed
	Dardenne M, Kelly P, Bach J, Savino W. Identification and functional activity of prolactin receptors in thymic epithelial cells. Proc Natl Acad Sci U S A. 1991;88:9700-4 pubmed
	Rozakis Adcock M, Kelly P. Mutational analysis of the ligand-binding domain of the prolactin receptor. J Biol Chem. 1991;266:16472-7 pubmed

product information

Product Type :

Antibody

Product Name :

Prolactin Receptor Monoclonal Antibody (T6)

Catalog # :

MA1-611

Quantity :

100 ug

Price :

US 451.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 1:25-1:200, Western Blot: 1 ug/mL

Species :

Human, Rat

Clone :

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Prolactin (PRL) is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. Immunoreactive PRL receptor (PRLR), a member of the cytokine receptor family, varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. PRLR consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region, the length of which appears to influence ligand binding and regulate cellular function.

Immunogen :

Purified rat liver PRL receptor.

Format :

Lyophilized

Applications w/Dilutions :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 1:25-1:200, Western Blot: 1 ug/mL

Aliases :

AI987712; cytokine receptor; HPRL; hPRL receptor; hPRLrI; Lactogen receptor; MFAB; pPRLR-SF; Pr-1; Pr-3; Prl R; PRLR; PRL-R; Prlr-rs1; Prolactin receptor; prolactin receptor 2 precursor; prolactin receptor related sequence 1; prolactin receptor short isoform; RATPRLR; secreted prolactin binding protein

more info or order :

Invitrogen product webpage