Gemin 3 Monoclonal Antibody (12H12) | Invitrogen MA1-5779 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Gemin 3 Monoclonal Antibody (12H12)

catalog :

MA1-5779

quantity :

100 uL

price :

US 592.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

12H12

The same clone is also sold as:

Santa Cruz Biotechnology: sc-57007 HRP, sc-57007 AC, sc-57007
Abcam: ab10305
BioLegend: 865502, 865501
ImmuQuest: IQ261

reactivity :

Chinese hamsters, human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 3

Reference
Van Itallie C, Lidman K, Tietgens A, Anderson J. Newly synthesized claudins but not occludin are added to the basal side of the tight junction. Mol Biol Cell. 2019;30:1406-1424 pubmed publisher
Tabariès S, McNulty A, Ouellet V, Annis M, Dessureault M, Vinette M, et al. Afadin cooperates with Claudin-2 to promote breast cancer metastasis. Genes Dev. 2019;33:180-193 pubmed publisher
Sartor G, Malvezzi A, Kumar A, Andrade N, Wiedner H, Vilca S, et al. Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins. J Neurosci. 2019;39:612-626 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Gemin 3 Monoclonal Antibody (12H12)

Catalog # :

MA1-5779

Quantity :

100 uL

Price :

US 592.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Hamster, Human, Mouse, Rat

Applications :

ELISA: Assay-dependent, Flow Cytometry: 1 ug for 10^6 cells, Immunocytochemistry: Assay-dependent, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Hamster, Human, Mouse, Rat

Clone :

12H12

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Gemin 3 is a member of the DEAD box protein family which are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. DEAD box proteins such as Gemin 3 are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of DEAD box family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Gemin 3 has an ATPase activity and a component of the survival of motor neurons (SMN) complex. The Gemin 3 protein may play a catalytic role in the function of the SMN complex on RNPs. Diseases associated with Gemin 3 protein dysfunction include spinal muscular dystrophy and muscular atrophy.

Immunogen :

Recombinant 6His-tag COOH-terminal domain of Gemin3 (amino acids 368-548) from SP2/0 cellsal domain of Gemin3.

Format :

Liquid

Applications w/Dilutions :

Aliases :

component of gems 3; DDX 20; DDX20; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; DEAD box protein 20; DEAD box protein DP 103; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD; DEAD/H BOX 20; DEAD-box helicase 20; DEAD-box protein DP103; DKFZP434H052; DP 103; Dp103; GEMIN3; Gemin-3; I79_021005; probable ATP-dependent RNA helicase DDX20; putative ATP-dependent RNA helicase DDX20; regulator of steroidogenic factor 1; ROSF-1; SMN-interacting protein