FceR1 alpha Monoclonal Antibody (CRA1 (AER37)) | Invitrogen MA1-4997 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FceR1 alpha Monoclonal Antibody (CRA1 (AER37))

catalog :

MA1-4997

quantity :

100 ug

price :

US 626.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CRA1 (AER37)

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, mass cytometry

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100; fig 3c	Sanyal R, Pavel A, Glickman J, Chan T, Zheng X, Zhang N, et al. Atopic dermatitis in African American patients is TH2/TH22-skewed with TH1/TH17 attenuation. Ann Allergy Asthma Immunol. 2019;122:99-110.e6 pubmed publisher
mass cytometry; human; loading ...; fig s3a	See P, Dutertre C, Chen J, Günther P, McGovern N, Irac S, et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017;356: pubmed publisher
flow cytometry; human; loading ...; fig st12	Villani A, Satija R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, et al. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. Science. 2017;356: pubmed publisher
flow cytometry; human; loading ...; fig 1d	Cottineau J, Kottemann M, Lach F, Kang Y, VÃ©ly F, Deenick E, et al. Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency. J Clin Invest. 2017;127:1991-2006 pubmed publisher
flow cytometry; human; loading ...; fig s4	Kumar D, Puan K, Andiappan A, Lee B, Westerlaken G, Haase D, et al. A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus. Genome Med. 2017;9:18 pubmed publisher
flow cytometry; human; loading ...; fig 4l	Henry E, Sy C, Inclan Rico J, Espinosa V, Ghanny S, Dwyer D, et al. Carbonic anhydrase enzymes regulate mast cell-mediated inflammation. J Exp Med. 2016;213:1663-73 pubmed publisher
immunocytochemistry; human; loading ...; fig 1a	Morshed M, Hlushchuk R, Simon D, Walls A, Obata Ninomiya K, Karasuyama H, et al. NADPH oxidase-independent formation of extracellular DNA traps by basophils. J Immunol. 2014;192:5314-23 pubmed publisher

product information

Product Type :

Antibody

Product Name :

FceR1 alpha Monoclonal Antibody (CRA1 (AER37))

Catalog # :

MA1-4997

Quantity :

100 ug

Price :

US 626.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human, Shrew

Applications :

Flow Cytometry: 1-5 ug/mL, Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): 1 ug/mL, Immunohistochemistry (Paraffin): 1 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL

Species :

Human, Shrew

Clone :

CRA1 (AER37)

Isotype :

IgG2b

Storage :

-20 C

Description :

FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE. Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one ß and two additional subunits. The latter two are required for signal transduction activity. The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released. The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma. The release of histamine and proteases leads to the synthesis of prostaglandins and leukotrienes-potent effectors of the hypersensitivity response.

Immunogen :

Region of FceR1 alpha (aa 26-197).

Format :

Liquid

Applications w/Dilutions :

Aliases :

alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3

more info or order :

Invitrogen product webpage