alpha Internexin Monoclonal Antibody (1D2) | Invitrogen MA1-4709 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

alpha Internexin Monoclonal Antibody (1D2)

catalog :

MA1-4709

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D2

The same clone is also sold as:

Rockland Immunochemicals: 900-301-D04
Novus Biologicals: NB300-216

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 2

Reference
Hayashi Y, Hsiao E, Sami S, Lancero M, Schlieve C, Nguyen T, et al. BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence. Proc Natl Acad Sci U S A. 2016;113:13057-13062 pubmed
Belmonte J, Clendenon S, Oliveira G, Swat M, Greene E, Jeyaraman S, et al. Virtual-tissue computer simulations define the roles of cell adhesion and proliferation in the onset of kidney cystic disease. Mol Biol Cell. 2016;27:3673-3685 pubmed

product information

Product Type :

Antibody

Product Name :

alpha Internexin Monoclonal Antibody (1D2)

Catalog # :

MA1-4709

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Many, Mouse, Rat

Applications :

Immunocytochemistry: 1:250-1:5,000, Immunohistochemistry: 1:1,000, Western Blot: 1:2,000

Species :

Human, Many, Mouse, Rat

Clone :

1D2

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

alpha-Internexin is a Class IV intermediate filament subunit expressed very early in neuronal development. It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. Many classes of mature neurons contain a-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons a-internexin is the only neurofilament subunit expressed. Antibodies to internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of a-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage. The use of antibodies to this protein in the study of brain tumors has not been examined to date, but is likely to be of interest.

Immunogen :

Recombinant rat alpha-internexin expressed in and purified from E. coli

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:250-1:5,000, Immunohistochemistry: 1:1,000, Western Blot: 1:2,000

Aliases :

66 kDa neurofilament protein; Alpha-internexin; alpha-Inx; AV028420; FLJ18662; FLJ57501; Ina; Inexa; internexin neuronal intermediate filament protein alpha; internexin neuronal intermediate filament protein, alpha; internexin, alpha; Intlaa; LOW QUALITY PROTEIN: alpha-internexin; MGC12702; NEF5; Neuro; Neurofilament 5; neurofilament 5 (66kD); Neurofilament 66; neurofilament-66; neurofilament-66, tax-binding protein; Nf66; NF-66; TXBP-1