CD56 Monoclonal Antibody (ERIC-1) | Invitrogen MA1-46055 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD56 Monoclonal Antibody (ERIC-1)

catalog :

MA1-46055

quantity :

100 µg

price :

US 474

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ERIC-1

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 2 ug/ml	Fischer C, Kleinschnitz K, Wrede A, Muth I, Kruse N, Nishino I, et al. Cell stress molecules in the skeletal muscle of GNE myopathy. BMC Neurol. 2013;13:24 pubmed publisher
immunocytochemistry; human	Zschüntzsch J, Voss J, Creus K, Sehmisch S, Raju R, Dalakas M, et al. Provision of an explanation for the inefficacy of immunotherapy in sporadic inclusion body myositis: quantitative assessment of inflammation and ?-amyloid in the muscle. Arthritis Rheum. 2012;64:4094-103 pubmed publisher
immunocytochemistry; human; 1:100	Hudelist G, Huber A, Auer M, Knöfler M, Saleh L, Hrachowitz C, et al. Administration of betaHCG leads to dose-dependent changes of gene expression signature of endometriotic stromal cells. Reprod Biomed Online. 2010;20:699-706 pubmed publisher
immunohistochemistry; human; 2 ug/ml	Muth I, Barthel K, Bahr M, Dalakas M, Schmidt J. Proinflammatory cell stress in sporadic inclusion body myositis muscle: overexpression of alphaB-crystallin is associated with amyloid precursor protein and accumulation of beta-amyloid. J Neurol Neurosurg Psychiatry. 2009;80:1344-9 pubmed publisher
immunohistochemistry; human; 1:200	Ferry J, Sohani A, Longtine J, Schwartz R, Harris N. HHV8-positive, EBV-positive Hodgkin lymphoma-like large B-cell lymphoma and HHV8-positive intravascular large B-cell lymphoma. Mod Pathol. 2009;22:618-26 pubmed publisher
	Gumede S, Abia A, Amoako D, Essack S. Analysis of Wastewater Reveals the Spread of Diverse Extended-Spectrum β-Lactamase-Producing E. coli Strains in uMgungundlovu District, South Africa. Antibiotics (Basel). 2021;10: pubmed publisher
	Velázquez R, Ferreira E, Tran A, Turner E, Belfiore R, Branca C, et al. Acute tau knockdown in the hippocampus of adult mice causes learning and memory deficits. Aging Cell. 2018;:e12775 pubmed publisher
	Benford H, Bolborea M, Pollatzek E, Lossow K, Hermans Borgmeyer I, Liu B, et al. A sweet taste receptor-dependent mechanism of glucosensing in hypothalamic tanycytes. Glia. 2017;65:773-789 pubmed publisher
	Fellegara G, D Adda T, Pilato F, Froio E, Ampollini L, Rusca M, et al. Genetics of a combined lung small cell carcinoma and large cell neuroendocrine carcinoma with adenocarcinoma. Virchows Arch. 2008;453:107-15 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD56 Monoclonal Antibody (ERIC-1)

Catalog # :

MA1-46055

Quantity :

100 µg

Price :

US 474

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:100-1:2,000, Flow Cytometry: 1:10-1:1,000, Immunocytochemistry: 1:10-1:500, Immunohistochemistry (Frozen): 1:10-1:500, Immunohistochemistry (Paraffin): 1:10-1:500, Immunoprecipitation: 1:10-1:500, Radioimmune assays: 1:100-1:2,000, Western Blot: 1:100-1:2,000

Species :

Human

Clone :

ERIC-1

Isotype :

IgG1

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.

Immunogen :

CD56 positive cells.

Format :

Liquid

Applications w/Dilutions :

Aliases :

adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM

more info or order :

Invitrogen product webpage