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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD11c Monoclonal Antibody (3.9)
catalog :
MA1-46052
quantity :
100 µg
price :
US 464
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3.9
reactivity :
human, rhesus macaque
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 4d
Sontag S, Förster M, Qin J, Wanek P, Mitzka S, Schüler H, et al. Modelling IRF8 Deficient Human Hematopoiesis and Dendritic Cell Development with Engineered iPS Cells. Stem Cells. 2017;35:898-908 pubmed publisher
  • flow cytometry; human; loading ...; fig 3a
Kelly A, Robinson M, Roche G, Biron C, O Farrelly C, Ryan E. Immune Cell Profiling of IFN-? Response Shows pDCs Express Highest Level of IFN-?R1 and Are Directly Responsive via the JAK-STAT Pathway. J Interferon Cytokine Res. 2016;36:671-680 pubmed
  • flow cytometry; human; loading ...; fig 1b
Slebioda T, Bojarska Junak A, Cyman M, Landowski P, Kaminska B, Celinski K, et al. Expression of death receptor 3 on peripheral blood mononuclear cells differes in adult IBD patients and children with newly diagnosed IBD. Cytometry B Clin Cytom. 2017;92:165-169 pubmed publisher
  • flow cytometry; human; fig 3
Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
  • immunohistochemistry; rhesus macaque; 1:10
Sestak K, Feely S, Fey B, Dufour J, Hargitt E, Alvarez X, et al. Experimental inoculation of juvenile rhesus macaques with primate enteric caliciviruses. PLoS ONE. 2012;7:e37973 pubmed publisher
  • flow cytometry; human
Giannelli S, Taddeo A, Presicce P, Villa M, Della Bella S. A six-color flow cytometric assay for the analysis of peripheral blood dendritic cells. Cytometry B Clin Cytom. 2008;74:349-55 pubmed publisher
  • flow cytometry; human; tbl 1
Tan P, Chan C, Xue S, Dong R, Ananthesayanan B, Manunta M, et al. Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells. Atherosclerosis. 2004;173:171-83 pubmed
  • flow cytometry; human; tbl 1
del Giudice I, Matutes E, Morilla R, Morilla A, Owusu Ankomah K, Rafiq F, et al. The diagnostic value of CD123 in B-cell disorders with hairy or villous lymphocytes. Haematologica. 2004;89:303-8 pubmed
  • immunohistochemistry - frozen section; human
Günther C, Wozel G, Dressler J, Meurer M, Pfeiffer C. Tissue eosinophilia in pemphigoid gestationis: association with eotaxin and upregulated activation markers on transmigrated eosinophils. Am J Reprod Immunol. 2004;51:32-9 pubmed
  • blocking or activating experiments; human
Bermudez L, Sangari F, Kolonoski P, Petrofsky M, Goodman J. The efficiency of the translocation of Mycobacterium tuberculosis across a bilayer of epithelial and endothelial cells as a model of the alveolar wall is a consequence of transport within mononuclear phagocytes and invasion of alveolar epithelial cel. Infect Immun. 2002;70:140-6 pubmed
  • flow cytometry; human
Semnani R, Sabzevari H, Iyer R, Nutman T. Filarial antigens impair the function of human dendritic cells during differentiation. Infect Immun. 2001;69:5813-22 pubmed
  • flow cytometry; rhesus macaque
Pichyangkul S, Saengkrai P, Yongvanitchit K, Limsomwong C, Gettayacamin M, Walsh D, et al. Isolation and characterization of rhesus blood dendritic cells using flow cytometry. J Immunol Methods. 2001;252:15-23 pubmed
Juul Madsen K, Qvist P, Bendtsen K, Langkilde A, Vestergaard B, Howard K, et al. Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4. J Immunol. 2020;204:1345-1361 pubmed publisher
van der Aa E, Buschow S, Biesta P, Janssen H, Woltman A. The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function. PLoS ONE. 2016;11:e0161235 pubmed publisher
Nunes Cabaço H, Matoso P, Foxall R, Tendeiro R, Pires A, Carvalho T, et al. Thymic HIV-2 infection uncovers posttranscriptional control of viral replication in human thymocytes. J Virol. 2015;89:2201-8 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD11c Monoclonal Antibody (3.9)
Catalog # :
MA1-46052
Quantity :
100 µg
Price :
US 464
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1 µg per million cells, Immunocytochemistry: 1:10-1:500, Immunohistochemistry (Frozen): 1:10-1:500, Immunoprecipitation: 1:10-1:500
Species :
Human
Clone :
3.9
Isotype :
IgG1
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.
Immunogen :
Synovial cells and human monocytes.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 µg per million cells, Immunocytochemistry: 1:10-1:500, Immunohistochemistry (Frozen): 1:10-1:500, Immunoprecipitation: 1:10-1:500
Aliases :
AI449405; CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; Cr4; integrin alpha X; integrin alpha-X; integrin aX; integrin subunit alpha X; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Itgax; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain; RGD1561123; SLEB6
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA