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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD171 Monoclonal Antibody (UJ127.11)
catalog :
MA1-46044
quantity :
100 µg
price :
US 474
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UJ127.11
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Invitrogen product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • western blot; human
Morales D, Townsend R, Malone J, Ewersmann C, Macy E, Inder T, et al. Alterations in protein regulators of neurodevelopment in the cerebrospinal fluid of infants with posthemorrhagic hydrocephalus of prematurity. Mol Cell Proteomics. 2012;11:M111.011973 pubmed publisher
Heiz M, Grünberg J, Schubiger P, Novak Hofer I. Hepatocyte growth factor-induced ectodomain shedding of cell adhesion molecule L1: role of the L1 cytoplasmic domain. J Biol Chem. 2004;279:31149-56 pubmed
product information
Product Type :
Antibody
Product Name :
CD171 Monoclonal Antibody (UJ127.11)
Catalog # :
MA1-46044
Quantity :
100 µg
Price :
US 474
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
ELISA: 1:100-1:2,000, Flow Cytometry: 2.5 µg/mL, Immunocytochemistry: 2 - 5 µg/mL, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: 1:10-1:500, Western Blot: 2 µg/mL
Species :
Human, Mouse
Clone :
UJ127.11
Isotype :
IgG1, kappa
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
Immunogen :
Homogenous suspension of 16 week human fetal brain.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:100-1:2,000, Flow Cytometry: 2.5 µg/mL, Immunocytochemistry: 2 - 5 µg/mL, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: 1:10-1:500, Western Blot: 2 µg/mL
Aliases :
antigen identified by monoclonal antibody R1; CAML1; CD 171; CD171; CD171 molecule; HSAS; HSAS1; Hyd; L1; L1 cell adhesion molecule; L1CAM; MASA; MIC5; N-CAM L1; NCAML1; N-CAML1; N-CAM-L1; NCAM-L1; Nerve-growth factor-inducible large external glycoprotein; neural cell adhesion molecule L1; NILE; S10; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM; SPG1
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA