This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Defensin 5 Monoclonal Antibody (8C8)
catalog :
MA1-46026
quantity :
100 uL
price :
US 480.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8C8

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, dot blot
citations: 1
Reference
Brabec T, Vobo x159 il M, Schierov xe1 D, Valter E, x160 pl xed chalov xe1 I, Dobe x161 J, et al. IL-17-driven induction of Paneth cell antimicrobial functions protects the host from microbiota dysbiosis and inflammation in the ileum. Mucosal Immunol. 2023;16:373-385 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Defensin 5 Monoclonal Antibody (8C8)
Catalog # :
MA1-46026
Quantity :
100 uL
Price :
US 480.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human
Applications :
Dot Blot: Assay-Dependent, ELISA: Assay-Dependent, Flow Cytometry: 1 ug per million cells, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 5-10 ug/mL, Western Blot: 1:1,000
Species :
Human
Clone :
8C8
Isotype :
IgG2b
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.
Immunogen :
Full-length proHD5 protein.
Format :
Liquid
Applications w/Dilutions :
Dot Blot: Assay-Dependent, ELISA: Assay-Dependent, Flow Cytometry: 1 ug per million cells, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 5-10 ug/mL, Western Blot: 1:1,000
Aliases :
DEF5; DEFA5; defensin 5; defensin alpha 5; Defensin, alpha 5; defensin, alpha 5, Paneth cell-specific; defensin, alpha 5, preproprotein; defensin-5; HD5; HD-5; HD5(20-94); HD5(23-94); HD5(29-94); HD5(56-94); HD5(63-94); MGC129728
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA