DR4 Monoclonal Antibody (32A242) | Invitrogen MA1-41049 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DR4 Monoclonal Antibody (32A242)

catalog :

MA1-41049

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

32A242

The same clone is also sold as:

Novus Biologicals: NBP2-27415, NB100-56528
OriGene: TA336389

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

DR4 Monoclonal Antibody (32A242)

Catalog # :

MA1-41049

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: Assay-Dependent, Western Blot: 1-3 ug/mL

Species :

Human, Mouse, Rat

Clone :

32A242

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).

Immunogen :

Synthetic peptide corresponding to residues 2-21 of mature human DR4.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-Dependent, Western Blot: 1-3 ug/mL

Aliases :

APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; sCD261; soluble CD261; soluble TRAIL; sTRAIL; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a