HTRA2 Monoclonal Antibody (196C429) | Invitrogen MA1-41040 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HTRA2 Monoclonal Antibody (196C429)

catalog :

MA1-41040

quantity :

100 ug

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

196C429

The same clone is also sold as:

Novus Biologicals: NBP2-80782, NB100-56558

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

HTRA2 Monoclonal Antibody (196C429)

Catalog # :

MA1-41040

Quantity :

100 ug

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:10-1:500, Western Blot: 2-3 ug/mL

Species :

Human

Clone :

196C429

Isotype :

IgG1, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity (1-3). Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli. This protein called Omi/HtrA2 is a mitochondrial protein that binds to IAP (4). Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis indicating that Omi could participate in the mitochondrial apoptotic pathway.

Immunogen :

Synthetic peptide corresponding to residues 335-350 of human Htra2.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:10-1:500, Western Blot: 2-3 ug/mL

Aliases :

AI481710; High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; mnd2; motor neuron degeneration 2; OMI; Omi stress-regulated endoprotease; PARK13; protease, serine, 25; Prss25; Serine protease 25; serine protease HTRA2, mitochondrial; serine protease OMI; serine proteinase OMI