TRF2 Monoclonal Antibody (4A794.15) | Invitrogen MA1-41001 product information

product summary

Loading...

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRF2 Monoclonal Antibody (4A794.15)

catalog :

MA1-41001

quantity :

100µg

price :

US 409

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4A794.15

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 5a	Mytych J, Romerowicz Misielak M, Koziorowski M. Long-term culture with lipopolysaccharide induces dose-dependent cytostatic and cytotoxic effects in THP-1 monocytes. Toxicol In Vitro. 2017;42:1-9 pubmed publisher
western blot; human; loading ...; fig 3e	Mytych J, Wos I, Solek P, Koziorowski M. Protective role of klotho protein on epithelial cells upon co-culture with activated or senescent monocytes. Exp Cell Res. 2017;350:358-367 pubmed publisher

image

image 1 :

product information

Product Type :

Antibody

Product Name :

TRF2 Monoclonal Antibody (4A794.15)

Catalog # :

MA1-41001

Quantity :

100µg

Price :

US 409

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ChIP assay: 1:10-1:500, ELISA: 2 µg/mL, Flow Cytometry: 0.1 µg/1x10^6 cells, Immunocytochemistry: 1:10-1:500, Immunofluorescence: 1:10-1:500, Immunohistochemistry (Frozen): 5 µg/mL, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: 2 µg/1x10^6 cells, Western Blot: 2-4 µg/mL

Species :

Human, Mouse, Rat

Clone :

4A794.15

Isotype :

IgG1, kappa

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1 contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types.

Immunogen :

Full-length TRF2 protein.

Format :

Liquid

Applications w/Dilutions :

ChIP assay: 1:10-1:500, ELISA: 2 µg/mL, Flow Cytometry: 0.1 µg/1x10^6 cells, Immunocytochemistry: 1:10-1:500, Immunofluorescence: 1:10-1:500, Immunohistochemistry (Frozen): 5 µg/mL, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: 2 µg/1x10^6 cells, Western Blot: 2-4 µg/mL

Aliases :

Telomeric DNA-binding protein; telomeric repeat binding factor 2; telomeric repeat binding protein 2; Telomeric repeat-binding factor 2; TERF2; TRBF2; TRF2; TTAGGG repeat-binding factor 2

more info or order :

Invitrogen product webpage