MARCO Monoclonal Antibody (PLK-1) | Invitrogen MA1-40315 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MARCO Monoclonal Antibody (PLK-1)

catalog :

MA1-40315

quantity :

100 ug

price :

US 738.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PLK-1

The same clone is also sold as:

OriGene: AM26207PU-N

reactivity :

human, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

product information

Product Type :

Antibody

Product Name :

MARCO Monoclonal Antibody (PLK-1)

Catalog # :

MA1-40315

Quantity :

100 ug

Price :

US 738.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Bovine, Human

Applications :

Flow Cytometry: Assay-dependent, Functional Assay: 1:50, Immunocytochemistry: 0.6 ug/mL, Immunohistochemistry (Frozen): 5 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Bovine, Human

Clone :

PLK-1

Isotype :

IgG3

Storage :

4 C

Description :

MARCO, also known as SR-A6 or SCARA2, is a macrophage surface receptor and a member of the class A scavenger receptor family. As a part of the innate antimicrobial immune system, MARCO can bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. Due to its expression in tumor infiltrating macrophages, and its role in inhibiting immune responses within tumor environment, MARCO has been indicated as a potential target for cancer immunotherapy.

Immunogen :

Human alveolar macrophages (recognizes domain V between residues 420 and 431)

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent, Functional Assay: 1:50, Immunocytochemistry: 0.6 ug/mL, Immunohistochemistry (Frozen): 5 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

AI323439; Ly112; macrophage receptor MARCO; Macrophage receptor with collagenous structure; MARCO; SCARA2; Scavenger receptor class A member 2; scavenger receptor class A, member 2; SR-A6