ASGR1 Monoclonal Antibody (8D7) | Invitrogen MA1-40244 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ASGR1 Monoclonal Antibody (8D7)

catalog :

MA1-40244

quantity :

100 µg

price :

US 600.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8D7

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100	Gieseck R, Hannan N, Bort R, Hanley N, Drake R, Cameron G, et al. Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture. PLoS ONE. 2014;9:e86372 pubmed publisher
	Li Z, Wu J, Wang L, Han W, Yu J, Liu X, et al. Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions. Cell Death Dis. 2019;10:763 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ASGR1 Monoclonal Antibody (8D7)

Catalog # :

MA1-40244

Quantity :

100 µg

Price :

US 600.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Rat

Applications :

ELISA: 1:50, Flow Cytometry: 1:50, Immunohistochemistry (Frozen): 1:50, Western Blot: 1:50

Species :

Human, Rat

Clone :

8D7

Isotype :

IgG1

Storage :

4° C

Description :

The asialoglycooprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediate the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed. The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.

Immunogen :

Crude rat liver membrane extracts

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:50, Flow Cytometry: 1:50, Immunohistochemistry (Frozen): 1:50, Western Blot: 1:50

Aliases :

ASGPR; ASGPR 1; ASGP-R 1; ASGPR1; ASGR; ASGR1; Asgr-1; asialoglycoprotein receptor (RHL1); asialoglycoprotein receptor 1; Asialoglycoprotein receptor 1 (hepatic lectin); asialoglycoprotein receptor RHL1; CLEC4H1; C-type lectin domain family 4 member H1; Hepatic lectin 1; hepatic lectin 1 RHL1; hepatic lectin 1, RHL1; hepatic lectin H1; HL-1; RATRHL1; RHL1; RHL-1; Unknown (protein for MGC:133691)

more info or order :

Invitrogen product webpage