Polymyxin B Monoclonal Antibody (45) | Invitrogen MA1-40133 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Polymyxin B Monoclonal Antibody (45)

catalog :

MA1-40133

quantity :

1 mL

price :

US 738.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

application :

western blot, ELISA, immunocytochemistry

citations: 4

Reference
Lu J, Azad M, Moreau J, Zhu Y, Jiang X, Tonta M, et al. Inwardly rectifying potassium channels mediate polymyxin-induced nephrotoxicity. Cell Mol Life Sci. 2022;79:296 pubmed publisher
Ahmed M, Velkov T, Zhou Q, Fulcher A, Callaghan J, Zhou F, et al. Intracellular localization of polymyxins in human alveolar epithelial cells. J Antimicrob Chemother. 2019;74:48-57 pubmed publisher
Ahmed M, Velkov T, Lin Y, Yun B, Nowell C, Zhou F, et al. Potential Toxicity of Polymyxins in Human Lung Epithelial Cells. Antimicrob Agents Chemother. 2017;61: pubmed publisher
Yoshino N, Endo M, Kanno H, Matsukawa N, Tsutsumi R, Takeshita R, et al. Polymyxins as novel and safe mucosal adjuvants to induce humoral immune responses in mice. PLoS ONE. 2013;8:e61643 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Polymyxin B Monoclonal Antibody (45)

Catalog # :

MA1-40133

Quantity :

1 mL

Price :

US 738.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Bacteria

Applications :

ELISA: 1:50, Western Blot: 1:10

Species :

Bacteria

Clone :

Isotype :

IgM

Storage :

4 C

Description :

The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either in vitro or in vivo. Antibodies to PMB allow for the quantitative study of interaction of PMB/LPS interactions.

Immunogen :

Polymixin B.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:50, Western Blot: 1:10

Aliases :

PMB