CD31 Monoclonal Antibody (ER-MP12) | Invitrogen MA1-40074 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD31 Monoclonal Antibody (ER-MP12)

catalog :

MA1-40074

quantity :

100 µg

price :

US 496.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

ER-MP12

reactivity :

mouse

application :

ELISA, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 3d	De Marchi E, Pegoraro A, Turiello R, Di Virgilio F, Morello S, Adinolfi E. A2A Receptor Contributes to Tumor Progression in P2X7 Null Mice. Front Cell Dev Biol. 2022;10:876510 pubmed publisher
immunohistochemistry - frozen section; mouse	Baptista A, Roozendaal R, Reijmers R, Koning J, Unger W, Greuter M, et al. Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation. elife. 2014;3: pubmed publisher
	Yi C, Liu J, Deng W, Luo C, Qi J, Chen M, et al. Old age promotes retinal fibrosis in choroidal neovascularization through circulating fibrocytes and profibrotic macrophages. J Neuroinflammation. 2023;20:45 pubmed publisher
	Wang H, Qi W, Zou C, Xie Z, Zhang M, Naito M, et al. NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation. Nat Commun. 2021;12:4826 pubmed publisher
	Zondervan R, Jenkins D, Reicha J, Hankenson K. Thrombospondin-2 spatiotemporal expression in skeletal fractures. J Orthop Res. 2021;39:30-41 pubmed publisher
	Zou C, Mifflin L, Hu Z, Zhang T, Shan B, Wang H, et al. Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and Aβ Accumulation in Alzheimer's Disease. Cell Rep. 2020;33:108447 pubmed publisher
	Edlinger L, Berger Becvar A, Menzl I, Hoermann G, Greiner G, Grundschober E, et al. Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1. Br J Haematol. 2017;179:229-241 pubmed publisher
	Dufek B, Meehan D, Delimont D, Cheung L, Gratton M, Phillips G, et al. Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease. Kidney Int. 2016;90:300-310 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD31 Monoclonal Antibody (ER-MP12)

Catalog # :

MA1-40074

Quantity :

100 µg

Price :

US 496.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Rat

Reactivity :

Mouse

Applications :

ELISA: 1:50, Flow Cytometry: 1:50, Immunohistochemistry (Frozen): 1:50, Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 1:50

Species :

Mouse

Clone :

ER-MP12

Isotype :

IgG2a

Storage :

4° C

Description :

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Immunogen :

Murine macrophage precursor hybrid W1C3cell hybrid

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:50, Flow Cytometry: 1:50, Immunohistochemistry (Frozen): 1:50, Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 1:50

Aliases :

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

more info or order :

Invitrogen product webpage