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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Collagen II Monoclonal Antibody (2B1.5)
catalog :
MA1-37493
quantity :
200 µg
price :
US 696.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B1.5
reactivity :
horses, guinea pig, domestic goat, human, mouse, rat, chicken, bovine, pigs , domestic sheep, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 74
Published Application/Species/Sample/Dilution | Reference |
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| Kremer A, Ribitsch I, Reboredo J, Dürr J, Egerbacher M, Jenner F, et al. Three-Dimensional Coculture of Meniscal Cells and Mesenchymal Stem Cells in Collagen Type I Hydrogel on a Small Intestinal Matrix-A Pilot Study Toward Equine Meniscus Tissue Engineering. Tissue Eng Part A. 2017;23:390-402 pubmed publisher
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| Bahmanpour S, Ghasemi M, Sadeghi Naini M, Kashani I. Effects of Platelet-Rich Plasma & Platelet-Rich Fibrin with and without Stromal Cell-Derived Factor-1 on Repairing Full-Thickness Cartilage Defects in Knees of Rabbits. Iran J Med Sci. 2016;41:507-517 pubmed
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| Perrier Groult E, Pasdeloup M, Malbouyres M, Galera P, Mallein Gerin F. Control of collagen production in mouse chondrocytes by using a combination of bone morphogenetic protein-2 and small interfering RNA targeting Col1a1 for hydrogel-based tissue-engineered cartilage. Tissue Eng Part C Methods. 2013;19:652-64 pubmed publisher
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| Hou B, Fukai N, Olsen B. Mechanical force-induced midpalatal suture remodeling in mice. Bone. 2007;40:1483-93 pubmed
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| Schreiweis M, Butler J, Kulkarni N, Knierman M, Higgs R, Halladay D, et al. A proteomic analysis of adult rat bone reveals the presence of cartilage/chondrocyte markers. J Cell Biochem. 2007;101:466-76 pubmed
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| Romito L, Ameer G. Mechanical interlocking of engineered cartilage to an underlying polymeric substrate: towards a biohybrid tissue equivalent. Ann Biomed Eng. 2006;34:737-47 pubmed
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| Lin Y, Luo E, Chen X, Liu L, Qiao J, Yan Z, et al. Molecular and cellular characterization during chondrogenic differentiation of adipose tissue-derived stromal cells in vitro and cartilage formation in vivo. J Cell Mol Med. 2005;9:929-39 pubmed
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| Hecht J, Hayes E, Haynes R, Cole W, Long R, Farach Carson M, et al. Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes. Differentiation. 2005;73:212-21 pubmed
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| Wang Y, Xiao R, Yang F, Karim B, Iacovelli A, Cai J, et al. Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse. Development. 2005;132:3537-48 pubmed
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| Peker S, Kurtkaya Yapicier O, Kilic T, Pamir M. Microsurgical anatomy of the lateral walls of the pituitary fossa. Acta Neurochir (Wien). 2005;147:641-8; discussion 649 pubmed
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| Ortega N, Behonick D, Colnot C, Cooper D, Werb Z. Galectin-3 is a downstream regulator of matrix metalloproteinase-9 function during endochondral bone formation. Mol Biol Cell. 2005;16:3028-39 pubmed
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| Kose G, Korkusuz F, Ozkul A, Soysal Y, Ozdemir T, Yildiz C, et al. Tissue engineered cartilage on collagen and PHBV matrices. Biomaterials. 2005;26:5187-97 pubmed
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| Bobryshev Y. Transdifferentiation of smooth muscle cells into chondrocytes in atherosclerotic arteries in situ: implications for diffuse intimal calcification. J Pathol. 2005;205:641-50 pubmed
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Gao X, Patwa A, Deng Z, Utsunomiya H, Grinstaff M, Ruzbarsky J, et al. Influence of fixation on CA4+ contrast enhanced microCT of articular cartilage and subsequent feasibility for histological evaluation. Am J Transl Res. 2021;13:8921-8937 pubmed
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Varela Eirin M, Carpintero Fernández P, Sánchez Temprano A, Varela Vazquez A, Paíno C, Casado Diaz A, et al. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. Aging (Albany NY). 2020;12:15882-15905 pubmed publisher
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Fernández Iglesias Á, Fuente R, Gil Peña H, Alonso Durán L, García Bengoa M, Santos F, et al. Innovative Three-Dimensional Microscopic Analysis of Uremic Growth Plate Discloses Alterations in the Process of Chondrocyte Hypertrophy: Effects of Growth Hormone Treatment. Int J Mol Sci. 2020;21: pubmed publisher
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Bolean M, Izzi B, Van Kerckhoven S, Bottini M, Ramos A, Millan J, et al. Matrix vesicle biomimetics harboring Annexin A5 and alkaline phosphatase bind to the native collagen matrix produced by mineralizing vascular smooth muscle cells. Biochim Biophys Acta Gen Subj. 2020;1864:129629 pubmed publisher
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Locker M, Kellermann O, Boucquey M, Khun H, Huerre M, Poliard A. Paracrine and autocrine signals promoting full chondrogenic differentiation of a mesoblastic cell line. J Bone Miner Res. 2004;19:100-10 pubmed
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Nakayama N, Duryea D, Manoukian R, Chow G, Han C. Macroscopic cartilage formation with embryonic stem-cell-derived mesodermal progenitor cells. J Cell Sci. 2003;116:2015-28 pubmed
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Dabovic B, Chen Y, Colarossi C, Zambuto L, Obata H, Rifkin D. Bone defects in latent TGF-beta binding protein (Ltbp)-3 null mice; a role for Ltbp in TGF-beta presentation. J Endocrinol. 2002;175:129-41 pubmed
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Wang W, Wang Y, Reginato A, Plotkina S, Gridley T, Olsen B. Growth defect in Grg5 null mice is associated with reduced Ihh signaling in growth plates. Dev Dyn. 2002;224:79-89 pubmed
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Dabovic B, Chen Y, Colarossi C, Obata H, Zambuto L, Perle M, et al. Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability. J Cell Biol. 2002;156:227-32 pubmed
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Odelberg S, Kollhoff A, Keating M. Dedifferentiation of mammalian myotubes induced by msx1. Cell. 2000;103:1099-109 pubmed
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product information
Product Type :
Antibody
Product Name :
Collagen II Monoclonal Antibody (2B1.5)
Catalog # :
MA1-37493
Quantity :
200 µg
Price :
US 696.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Bovine, Chicken, Human, Mouse, Rat
Applications :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1:200-1:400, Western Blot: 1:50
Species :
Bovine, Chicken, Human, Mouse, Rat
Clone :
2B1.5
Isotype :
IgG2a, kappa
Storage :
4° C
Description :
COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
Immunogen :
A purified preparation of lathyritic type II collagen from embryonic chicken sternum
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1:200-1:400, Western Blot: 1:50
Aliases :
alpha 1 type II procollagen; alpha 1 type IIA collagen; alpha 1 type IIA collagen precursor; alpha collagen type II; alpha-1 type II collagen; ANFH; AOM; arthroophthalmopathy, progressive (Stickler syndrome); cartilage collagen; CB11; CG2A1A; CGA; Chondrocalcin; COL11A3; Col2; Col2a; col2a1; Col2a-1; col2a1.L; col2a1a; col2a1-a; col2a1-b; Collagen 2; Collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen type II (Col2A1) gene, enhancer region; collagen type II alpha 1 chain; collagen type IIA; collagen, type II, alpha 1; collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital); collagen, type II, alpha 1 L homeolog; COLLII; cyanogen bromide; Del1; disproportionate micromelia; Dmm; Lpk; M100856; MGC131516; pro alpha1 type II collagen; pro-alpha 1(II); pro-alpha-1 type II collagen; procollagen alpha 1(II); Procollagen II alpha 1; procollagen, type II, alpha 1; Rgsc856; SEDC; STL1; type II collagen; type II collagen cyanogen bromide fragment CB10; type II collogen cyanogen bromide fragment CB8; unnamed protein product; X-col II; xcol2a1; XELAEV_18013523mg
more info or order :
company information

Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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