MVP Monoclonal Antibody (LRP-56) | Invitrogen MA1-35743 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MVP Monoclonal Antibody (LRP-56)

catalog :

MA1-35743

quantity :

1 mL

price :

US 676.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LRP-56

The same clone is also sold as:

OriGene: AM32055SU-N

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 5

Reference
Pizzolato G, Moparthi L, S xf6 derholm S, Cant xf9 C, Koch S. The oncogenic transcription factor FOXQ1 is a differential regulator of Wnt target genes. J Cell Sci. 2022;135: pubmed publisher
Miao Y, Ha A, de Lau W, Yuki K, Santos A, You C, et al. Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo. Cell Stem Cell. 2020;27:840-851.e6 pubmed publisher
Fenderico N, van Scherpenzeel R, Goldflam M, Proverbio D, Jordens I, Kralj T, et al. Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells. Nat Commun. 2019;10:365 pubmed publisher
Huang S, Fantini D, Merrill B, Bagchi S, Guzman G, Raychaudhuri P. DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer. Cancer Res. 2017;77:6562-6575 pubmed publisher
Jönsson Videsäter K, Andersson G, Bergh J, Paul C. Doxorubicin-resistant, MRP1-expressing U-1285 cells are sensitive to idarubicin. Ther Drug Monit. 2003;25:331-9 pubmed

product information

Product Type :

Antibody

Product Name :

MVP Monoclonal Antibody (LRP-56)

Catalog # :

MA1-35743

Quantity :

1 mL

Price :

US 676.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1:50, Immunocytochemistry: 1:20, Immunohistochemistry (Frozen): 1:20, Immunohistochemistry (Paraffin): 1:20

Species :

Human

Clone :

LRP-56

Isotype :

IgG2b

Storage :

4 C

Description :

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.

Immunogen :

Proprietary immunogen.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50, Immunocytochemistry: 1:20, Immunohistochemistry (Frozen): 1:20, Immunohistochemistry (Paraffin): 1:20

Aliases :

2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP