Cytokeratin 4 Monoclonal Antibody (6B10) | Invitrogen MA1-35558 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cytokeratin 4 Monoclonal Antibody (6B10)

catalog :

MA1-35558

quantity :

1 mL

price :

US 484.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6B10

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; fig 2	Qi H, Zheng X, Yuan X, Pflugfelder S, Li D. Potential localization of putative stem/progenitor cells in human bulbar conjunctival epithelium. J Cell Physiol. 2010;225:180-5 pubmed publisher
immunohistochemistry; human; 1:50	Locke M, Hyland P, Irwin C, Mackenzie I. Modulation of gingival epithelial phenotypes by interactions with regionally defined populations of fibroblasts. J Periodontal Res. 2008;43:279-89 pubmed publisher
	Crowley L, Cambuli F, Aparicio L, Shibata M, Robinson B, Xuan S, et al. A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors. elife. 2020;9: pubmed publisher
	Toivola D, Zhou Q, English L, Omary M. Type II keratins are phosphorylated on a unique motif during stress and mitosis in tissues and cultured cells. Mol Biol Cell. 2002;13:1857-70 pubmed

product information

Product Type :

Antibody

Product Name :

Cytokeratin 4 Monoclonal Antibody (6B10)

Catalog # :

MA1-35558

Quantity :

1 mL

Price :

US 484.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Frozen): 1:20, Immunohistochemistry (Paraffin): 1:10, Western Blot: Assay-dependent

Species :

Human

Clone :

6B10

Isotype :

IgG1

Storage :

4 C

Description :

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9-7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Immunogen :

Cytokeratin purified from human esophagus

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): 1:20, Immunohistochemistry (Paraffin): 1:10, Western Blot: Assay-dependent

Aliases :

57kd keratin; 57kDa keratin; AW108092; cb59; CK4; CK-4; CYK4; cytokeratin; cytokeratin 4; cytokeratin-4; Cytoskeletal 57 kDa keratin; etID20321.6; intermediate filament protein; K4; Kb4; keratin 4; keratin 4, type II; keratin 8; keratin complex 2, basic, gene 4; keratin, type II cytoskeletal 4; Keratin-4; Krt-2.4; Krt2-4; Krt4; krt4 {ECO:0000250; krt4 protein; krt8; type II basic cytokeratin; type II keratin Kb4; type-II keratin Kb4; UniProtKB:P19013}; WSN1; wu:fa91a11; wu:fd19e09; wu:fl23c09; zf-K8

more info or order :

Invitrogen product webpage