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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GFAP Monoclonal Antibody (6F2)
catalog :
MA1-35377
quantity :
1 mL
price :
US 486.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6F2
reactivity :
Japanese rice fish, human
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Invitrogen product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; Japanese rice fish; 1:500
Chi S, Wu Y, Cheng T. Persistent infection of betanodavirus in a novel cell line derived from the brain tissue of barramundi Lates calcarifer. Dis Aquat Organ. 2005;65:91-8 pubmed
Haberler C, Jarius C, Lang S, Rossler K, Gruber A, Hainfellner J, et al. Fibrous meningeal tumours with extensive non-calcifying collagenous whorls and glial fibrillary acidic protein expression: the whorling-sclerosing variant of meningioma. Neuropathol Appl Neurobiol. 2002;28:42-7 pubmed
product information
Product Type :
Antibody
Product Name :
GFAP Monoclonal Antibody (6F2)
Catalog # :
MA1-35377
Quantity :
1 mL
Price :
US 486.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Human
Applications :
Immunocytochemistry: 1:25-1:100, Immunohistochemistry (Frozen): 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50
Species :
Human
Clone :
6F2
Isotype :
IgG1
Storage :
4 C
Description :
GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
Immunogen :
GFAP from human brain.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:25-1:100, Immunohistochemistry (Frozen): 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50
Aliases :
6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA