CEACAM8 Monoclonal Antibody (80H3) | Invitrogen MA1-34517 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CEACAM8 Monoclonal Antibody (80H3)

catalog :

MA1-34517

quantity :

40 ug

price :

US 323.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

80H3

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - frozen section, mass cytometry

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
mass cytometry; human; loading ...; fig 1b, 1d, s2	Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CEACAM8 Monoclonal Antibody (80H3)

Catalog # :

MA1-34517

Quantity :

40 ug

Price :

US 323.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1:50-1:100, Functional Assay: Assay-dependent, Immunohistochemistry (Frozen): 1:25-1:100, Western Blot: Assay-dependent

Species :

Human

Clone :

80H3

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Immunogen :

Human leukocytes from individuals with CML.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:100, Functional Assay: Assay-dependent, Immunohistochemistry (Frozen): 1:25-1:100, Western Blot: Assay-dependent

Aliases :

carcinoembryonic antigen CGM6; carcinoembryonic antigen gene family member 6; carcinoembryonic antigen related cell adhesion molecule 8; carcinoembryonic antigen-related cell adhesion molecule 8; CD66b; CD67; CD67 antigen; CEACAM8; CGM6; NCA-95; non-specific cross-reacting antigen NCA-95

more info or order :

Invitrogen product webpage