Myeloperoxidase Monoclonal Antibody (2C7) | Invitrogen MA1-34067 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Myeloperoxidase Monoclonal Antibody (2C7)

catalog :

MA1-34067

quantity :

40 ug

price :

US 434.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2C7

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:2500; fig 7, 8	Naegelen I, PlanÃ§on S, Nicot N, Kaoma T, Muller A, Vallar L, et al. An essential role of syntaxin 3 protein for granule exocytosis and secretion of IL-1Î±, IL-1Î², IL-12b, and CCL4 from differentiated HL-60 cells. J Leukoc Biol. 2015;97:557-71 pubmed publisher
	Cao T, Yuan X, Fang H, Chen J, Xue K, Li Z, et al. Neutrophil extracellular traps promote keratinocyte inflammation via AIM2 inflammasome and AIM2-XIAP in psoriasis. Exp Dermatol. 2023;32:368-378 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Myeloperoxidase Monoclonal Antibody (2C7)

Catalog # :

MA1-34067

Quantity :

40 ug

Price :

US 434.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1:1,000-1:5,000, Immunohistochemistry (Paraffin): 1:500-1:1,000, Western Blot: Assay-dependent

Species :

Human

Clone :

2C7

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.

Immunogen :

Human myeloperoxidase

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1:1,000-1:5,000, Immunohistochemistry (Paraffin): 1:500-1:1,000, Western Blot: Assay-dependent

Aliases :

84 kDa myeloperoxidase; 89 kDa myeloperoxidase; mKIAA4033; MPO; Myeloperoxidase; Myeloperoxidase heavy chain; Myeloperoxidase light chain

more info or order :

Invitrogen product webpage